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In Germany, children with cancer have a high probability of survival
Date:11/24/2009

very beginning of the investigation it was clear that reliable quality indicators for procedures and infrastructure are lacking in paediatric oncology in Germany. Cross-sectional studies were therefore identified that described at least some features of infrastructure. This includes, for example, facilities in the largest hospitals, palliative care, and the situation regarding psychosocial services. However, there was no information on smaller hospitals and their infrastructure.

80% of children survive at least 5 years

IQWiG restricted the investigation to the most common oncological diseases. Children and adolescents who had acute lymphoblast leukaemia (ALL) or acute myeloid leukaemia (AML), non-Hodgkin lymphomas (NHL), Hodgkin's disease or tumours in the central nervous system (CNS) were included.

IQWiG came to the conclusion that overall more than 80% of children with cancer in Germany between 2000 and 2004 survived at least 5 years. 90% of children with cancer received treatment here in Germany in therapy-optimizing studies, which is also an indicator of a high standard of care. When survival probability is compared internationally, medical care in paediatric oncology is very good in Germany. Over the last 20 to 30 years it has improved markedly.

During the "submission of comments" procedure, references to additional publications were given by the professional association, which could then be incorporated into the final report. Thus, IQWiG was able to additionally assess the "event-free survival" outcome of children diagnosed with high-grade brain tumours.

Lack of studies on important outcomes

However, on other important patient-relevant outcomes, such as "health-related quality of life" and "pain", there was a paucity of studies. For the "deaths due to therapy" outcome, studies on AML and ALL as well as NHL could be located, but there are no clinical comparisons for Hodgkin's disease and CNS tu
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Contact: Dr. Anna-Sabine Ernst
info@iqwig.de
49-022-135-6850
Institute for Quality and Efficiency in Health Care
Source:Eurekalert

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