Navigation Links
In Diabetes, Any Protein in Urine May Signal Heart Risk
Date:8/31/2012

THURSDAY, Aug. 30 (HealthDay News) -- Any amount of measurable protein in the urine -- even if it is within the normal range -- may increase the risk of heart problems in people with type 2 diabetes, according to a new study.

The findings, published online Aug. 30 in the Journal of the American Society of Nephrology, could help identify patients who should be treated with heart protective drugs, the researchers said.

Some diabetes patients have kidney problems that lead to increased amounts of the protein albumin in their urine, a condition called albuminuria. These patients have a considerably higher risk of heart problems -- such as heart attack, stroke and heart failure -- than diabetes patients or people in the general population with normal urinary albumin levels.

At least 90 percent of diabetes patients have normal urinary albumin levels, but a group of Italian researchers wanted to find out if even they might be at increased risk for heart problems.

The team examined the relationship between albumin levels and heart problems in more than 1,200 type 2 diabetes patients who were followed for an average of about nine years. They found that any amount of measurable albumin excretion in the urine was associated with significant heart risks.

As the level of albumin excreted in urine rose, so too did the patient's risk for heart problems. Even slight elevations in excreted albumin were linked to raised odds for heart trouble, the researchers found.

However, although an association was noted between albuminuria and heart troubles, the study did not prove cause and effect.

The researchers also looked at a subgroup of patients who took high blood pressure drugs called ACE inhibitors from the start of the study and throughout the follow-up period. There was no link between albumin excretion levels and heart risks in this group.

This suggests that ACE inhibitors may help protect the hearts of both diabetes patients with albuminuria and those with normal albumin levels, Dr. Giuseppe Remuzzi, of the Mario Negri Institute for Pharmacological Research in Bergamo, and colleagues said in a news release from the American Society of Nephrology.

Further research is needed to determine the levels of albumin excretion that warrant treatment with heart-protective drugs, the study authors said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes, heart disease and stroke.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Aug. 30, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cellular pathway linked to diabetes, heart disease
2. 1 size doesnt fit all when treating blood pressure in people with diabetes, VA/U-M study suggests
3. Childhood Abuse Linked to Diabetes, Heart Disease in Middle-Aged Women
4. Warwick scientists uncover how checkpoint proteins bind chromosomes
5. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
6. Unusual protein helps regulate key cell communication pathway
7. Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
8. RANK protein promotes the initiation, progression and metastasis of human breast cancer
9. Protein may represent a switch to turn off B cell lymphoma
10. Protein RAL associated with aggressive characteristics in prostate, bladder and skin cancers
11. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
In Diabetes, Any Protein in  Urine May Signal Heart Risk
(Date:5/24/2016)... ... May 24, 2016 , ... Women's ... , Roberta Jordan is a Certified Nurse Midwife who was born and raised ... then went on to complete her masters degree from the University of Mexico. ...
(Date:5/24/2016)... ... 24, 2016 , ... Educational opportunities, and therefore life chances, ... communities providing richer opportunities. Recognizing the key role of housing in this system, ... school choice policies; (c) school desegregation policies; (d) wealth-focused policies; and (e) housing-focused ...
(Date:5/24/2016)... ... 24, 2016 , ... Regenerative Medicine is being transformed by ongoing research and ... protocols and patient results as have been achieved with Okyanos Cell Therapy ... of care for patients worldwide. , As the Medical Advisory Chairman at Okyanos, Eric ...
(Date:5/24/2016)... ... 2016 , ... Backed by decades of experience, Metroloji Okulu ... the best suited solution to meet regulatory requirements. Their professional staff also performs ... Istanbul. , Metroloji Okulu specializes in MadgeTech’s line of medical and pharmaceutical ...
(Date:5/24/2016)... ... May 24, 2016 , ... American Gene Technologies ... to its board of directors. Otterstatter is co-founder, president and CEO of ... technological innovations that lead to broad-based healthcare solutions. , “Jon knows how to ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016 ... beide primären Endpunkte und demonstriert ... in ‚ausgezeichneter plus guter , ...    ,      (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ... heute neue positive Daten von der MORA-Studie der ...
(Date:5/24/2016)... LAWRENCE, Mass. , May 24, 2016  NxStage ... medical technology company focused on advancing renal care, today ... Officer, plans to participate in the following schedule of ... will be made available at http://ir.nxstage.com/ . ... Jefferies Healthcare Conference NY, NY           Friday, ...
(Date:5/24/2016)... , May 24, 2016 ... de doble terapia del mundo, introduce catéteres para ... OrbusNeich, una compañía global especializada en ... vidas, ha expandido su cartera incluyendo productos para ... JADE™ y Scoreflex™ PTA son los dispositivos de ...
Breaking Medicine Technology: