Navigation Links
In Diabetes, Any Protein in Urine May Signal Heart Risk
Date:8/31/2012

THURSDAY, Aug. 30 (HealthDay News) -- Any amount of measurable protein in the urine -- even if it is within the normal range -- may increase the risk of heart problems in people with type 2 diabetes, according to a new study.

The findings, published online Aug. 30 in the Journal of the American Society of Nephrology, could help identify patients who should be treated with heart protective drugs, the researchers said.

Some diabetes patients have kidney problems that lead to increased amounts of the protein albumin in their urine, a condition called albuminuria. These patients have a considerably higher risk of heart problems -- such as heart attack, stroke and heart failure -- than diabetes patients or people in the general population with normal urinary albumin levels.

At least 90 percent of diabetes patients have normal urinary albumin levels, but a group of Italian researchers wanted to find out if even they might be at increased risk for heart problems.

The team examined the relationship between albumin levels and heart problems in more than 1,200 type 2 diabetes patients who were followed for an average of about nine years. They found that any amount of measurable albumin excretion in the urine was associated with significant heart risks.

As the level of albumin excreted in urine rose, so too did the patient's risk for heart problems. Even slight elevations in excreted albumin were linked to raised odds for heart trouble, the researchers found.

However, although an association was noted between albuminuria and heart troubles, the study did not prove cause and effect.

The researchers also looked at a subgroup of patients who took high blood pressure drugs called ACE inhibitors from the start of the study and throughout the follow-up period. There was no link between albumin excretion levels and heart risks in this group.

This suggests that ACE inhibitors may help protect the hearts of both diabetes patients with albuminuria and those with normal albumin levels, Dr. Giuseppe Remuzzi, of the Mario Negri Institute for Pharmacological Research in Bergamo, and colleagues said in a news release from the American Society of Nephrology.

Further research is needed to determine the levels of albumin excretion that warrant treatment with heart-protective drugs, the study authors said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes, heart disease and stroke.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Aug. 30, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cellular pathway linked to diabetes, heart disease
2. 1 size doesnt fit all when treating blood pressure in people with diabetes, VA/U-M study suggests
3. Childhood Abuse Linked to Diabetes, Heart Disease in Middle-Aged Women
4. Warwick scientists uncover how checkpoint proteins bind chromosomes
5. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
6. Unusual protein helps regulate key cell communication pathway
7. Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
8. RANK protein promotes the initiation, progression and metastasis of human breast cancer
9. Protein may represent a switch to turn off B cell lymphoma
10. Protein RAL associated with aggressive characteristics in prostate, bladder and skin cancers
11. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
In Diabetes, Any Protein in  Urine May Signal Heart Risk
(Date:6/27/2016)... ... 2016 , ... TherapySites, the leading website and ... Tennessee Counseling Association. This new relationship allows TherapySites to continue to extend ... exclusive benefits and promotional offers. , "TCA is extremely excited about this new ...
(Date:6/27/2016)... , ... June 27, 2016 , ... ... edge technology to revolutionize the emergency ambulance transport experience for the millions of ... of how Uber has disrupted the taxi industry through the use of technology. ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, ... remain in the eye of the beholder, according to experts who offered insights and ... Journal of Managed Care. For the full issue, click here . , For ...
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
Breaking Medicine Technology: