Navigation Links
In Diabetes, Any Protein in Urine May Signal Heart Risk
Date:8/31/2012

THURSDAY, Aug. 30 (HealthDay News) -- Any amount of measurable protein in the urine -- even if it is within the normal range -- may increase the risk of heart problems in people with type 2 diabetes, according to a new study.

The findings, published online Aug. 30 in the Journal of the American Society of Nephrology, could help identify patients who should be treated with heart protective drugs, the researchers said.

Some diabetes patients have kidney problems that lead to increased amounts of the protein albumin in their urine, a condition called albuminuria. These patients have a considerably higher risk of heart problems -- such as heart attack, stroke and heart failure -- than diabetes patients or people in the general population with normal urinary albumin levels.

At least 90 percent of diabetes patients have normal urinary albumin levels, but a group of Italian researchers wanted to find out if even they might be at increased risk for heart problems.

The team examined the relationship between albumin levels and heart problems in more than 1,200 type 2 diabetes patients who were followed for an average of about nine years. They found that any amount of measurable albumin excretion in the urine was associated with significant heart risks.

As the level of albumin excreted in urine rose, so too did the patient's risk for heart problems. Even slight elevations in excreted albumin were linked to raised odds for heart trouble, the researchers found.

However, although an association was noted between albuminuria and heart troubles, the study did not prove cause and effect.

The researchers also looked at a subgroup of patients who took high blood pressure drugs called ACE inhibitors from the start of the study and throughout the follow-up period. There was no link between albumin excretion levels and heart risks in this group.

This suggests that ACE inhibitors may help protect the hearts of both diabetes patients with albuminuria and those with normal albumin levels, Dr. Giuseppe Remuzzi, of the Mario Negri Institute for Pharmacological Research in Bergamo, and colleagues said in a news release from the American Society of Nephrology.

Further research is needed to determine the levels of albumin excretion that warrant treatment with heart-protective drugs, the study authors said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about diabetes, heart disease and stroke.

-- Robert Preidt

SOURCE: American Society of Nephrology, news release, Aug. 30, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Cellular pathway linked to diabetes, heart disease
2. 1 size doesnt fit all when treating blood pressure in people with diabetes, VA/U-M study suggests
3. Childhood Abuse Linked to Diabetes, Heart Disease in Middle-Aged Women
4. Warwick scientists uncover how checkpoint proteins bind chromosomes
5. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
6. Unusual protein helps regulate key cell communication pathway
7. Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
8. RANK protein promotes the initiation, progression and metastasis of human breast cancer
9. Protein may represent a switch to turn off B cell lymphoma
10. Protein RAL associated with aggressive characteristics in prostate, bladder and skin cancers
11. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
In Diabetes, Any Protein in  Urine May Signal Heart Risk
(Date:10/13/2017)... (PRWEB) , ... October 13, ... ... School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, ... professionals on guideline updates for the primary prevention of cardiovascular diseases during ...
(Date:10/13/2017)... N.J. (PRWEB) , ... October 13, 2017 , ... The ... Holly Day Market. Featuring a collection of specialty vendors and unique items from across ... personalized and quality-focused health and wellness services offered by the VNA. The boutique ...
(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), an ... showcase a range of technology and learning solutions at the 68th Annual American ... to be held October 14–18, 2017 at the Mandalay Bay Resort in Las ...
(Date:10/12/2017)... , ... October 12, 2017 , ... IsoComforter, Inc. ( ... announced today the introduction of an innovative new design of the shoulder pad. ... you get maximum comfort while controlling your pain while using cold therapy. By utilizing ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... 2017  Commended for their devotion to personalized service, SMP ... number one in the South Florida Business Journal,s 50 Fastest-Growing ... yearly list, the national specialty pharmacy has found its niche.  ... will soon be honored by SFBJ as the 2017 Power ... Set to receive his award in October, Bardisa said of ...
(Date:9/22/2017)... 2017  As the latest Obamacare repeal effort moves ... (R-LA) and Lindsey Graham (R-SC) medical ... device industry is in an odd place.  The industry ... excise tax on medical device sales passed along with ... patients, increased visits and hospital customers with the funding ...
(Date:9/18/2017)... 2017 EpiVax, Inc. ("EpiVax") a ... immune engineering, today announced a new NIH-funded ... ... and presents a challenge for traditional flu ... be effective. Using state-of-the-art bioinformatics and molecular modeling methods, ...
Breaking Medicine Technology: