Navigation Links
Improving recovery from spinal cord injury
Date:6/9/2010

. They then let the rats recover for another three weeks before assessing the degree of recovery.

Using a well-established, 21-point scale where zero represents paralysis and 21 is normal function, the team of researchers assesed treated and untreated rats for a range of functions including whether they could lift their feet off the ground and whether they had coordinated leg movements. The initial injury rendered all rats to score below four, and all rats, treated or not, recovered somewhat by the end of two weeks. By the end of five weeks after injury most untreated rats scored 12 or less, while most treated rats scored better than 15. "The difference in coordination control was most remarkable," says Schnaar.

In addition to motor control, spinal cord injury can cause other nervous system problems, including losing the ability to control blood pressure and heart rate. To see if sialidase treatment improved nerve connections enough to remedy these problems, the team measured the nerve circuits that control blood pressure in treated and untreated rats. They found that treated animals improved blood pressure control. "We interpret this as improved communication in the spinal cord," says Schnaar.

Finally, the team looked at the nerve ends under a microscope and found that indeed, treated nerves showed an increased number of "sprouted" nerve ends, which according to Schnaar, provided anatomical evidence to add to the functional evidence that "something is going on."

"The positive is that we have shown functional recovery in a relevant animal model of spinal cord injury," says Schnaar. "That being said, we haven't done full toxicity studies on these rats, which definitely needs to be done before we think about taking the long road into using this as a drug in people; efficacy in animals also doesn't necessarily translate to humans."


'/>"/>

Contact: Audrey Huang
audrey@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ACR task force makes recommendations for improving relationships between radiologists and hospitals
2. Report Finds Control of High Blood Pressure Improving
3. Improving the health of all the worlds children
4. Survival in metastatic breast cancer patients is improving: targeted therapies have contributed
5. Amistaff Launches RN Medical/Surgical & RN Pharmacology Exams Using New Validation Process Focused on Improving Quality of Patient Care
6. Health Occupations Students of America, Inc. and the U.S. Army Sign Memorandum of Understanding in Support of Improving Career Options for Nations Students
7. Care improving, cost saving Indiana Network for Patient Care expands
8. Improving care for low-birth-weight infants
9. Morehead Presents Webinar on "When Satisfaction Isn't Enough: Improving RN Engagement"
10. Global Hospitals and Healthcare Suppliers Focus on Cutting Costs and Improving Quality at 2010 GHX Supply Chain Summit
11. Charging less for more effective treatments could reduce health care costs while improving health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... (PRWEB) July 31, 2014 Etymotic ... announced a new sponsorship of the DrumLine Battle® ... are Etymotic’s hearing protection products ETY•Plugs® and Music•PRO® ... against the harmful effects of high-level sound. Etymotic ... sponsorship at the Drum Corps International Championships on ...
(Date:7/31/2014)... black women put concerns about their hair above their ... the U.S. Centers for Disease Control and Prevention that ... States are overweight or obese. Yet some of them ... their hair restyled or restraightened, the University of Colorado ... also noted a shift toward more "low-maintenance" hairstyles, which ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Rich Dad® ... charity yard sale to benefit Habitat for Humanity. The yard ... was raised with 100% of the proceeds donated to Habitat ... items not sold at the event were donated to the ... Road, North Fort Myers, Florida 33903. , Of the ...
(Date:7/31/2014)... aimed to diagnose pediatric patients with suspected appendicitis ... without affecting diagnostic accuracy, Mayo Clinic Children,s Center ... in the journal Surgery . , Acute ... abdominal pain in children. Appendicitis occurs when the ... scans are often used to diagnose acute appendicitis ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Insight Accelerator ... a Series A round of investment for $4.6 million ... device for collecting vital signs. The company joined ... technology to fruition with the help of Insight development ... our reason for launching the Accelerator,” says Steve McPhilliamy, ...
Breaking Medicine News(10 mins):Health News:Etymotic Research Becomes The Official Hearing Protection Sponsor Of DrumLine Battle 2Health News:Hairdo Trumps Exercise for Many Black Women, Study Finds 2Health News:Rich Dad Education Charity Yard Sale to Benefit Habitat for Humanity of Lee and Hendry Counties a Success 2Health News:Insight Accelerator Labs Advances Member Toward Commercialization 2Health News:Insight Accelerator Labs Advances Member Toward Commercialization 3
... rats finds that even one injection leads to dependent ... naturally occurring protein plays a role in the disrupted ... with drug and alcohol dependence, says a new study. ... changes in association with drug abuse, it could potentially ...
... May 28 (HealthDay News) --Should it worry you that there ... , Not especially, when you consider that there are 44 ... , This information comes to you from scientists at the ... same techniques that enabled them to map the human genetic ...
... Controlling Weight before PregnancyWHITE PLAINS, N.Y., May 28 ... right amount during pregnancy is critical to giving a ... Dimes said today in response to new guidelines from ... issued new guidelines for the amount of weight a ...
... Logistics (NGL), a premier provider of mission critical transportation, service/spare parts ... network of forward stocking locations (FSL,s). , ... Broomfield, ... provider of mission critical transportation, service/spare parts logistics , and ...
... Perot Systems, RCS advantages of increased cash flows and ... providersPLANO, Texas, May 28 Amerinet, a leading national ... PER ) ( www.perotsystems.com ) ... Systems revenue cycle solutions available to Amerinet,s acute and ...
... Patent Covers High-throughput, Anchorage-independent Assay for Screening Compounds ... Falcon Genomics, Inc. announced today that it ... covering the Company,s Cancer BioChip System (CBCS) for ... in a high-throughput in vitro setting ...
Cached Medicine News:Health News:Study Finds Multitude of Bacteria on Human Skin 2Health News:Study Finds Multitude of Bacteria on Human Skin 3Health News:New Guidelines to Fight Obesity in Pregnancy Issued 2Health News:New Guidelines to Fight Obesity in Pregnancy Issued 3Health News:NGL Expands Global Network to Service Parts Logistics Customers 2Health News:NGL Expands Global Network to Service Parts Logistics Customers 3Health News:Perot Systems to Supply Revenue Cycle Solutions to Amerinet Members Nationwide 2Health News:Perot Systems to Supply Revenue Cycle Solutions to Amerinet Members Nationwide 3Health News:Falcon Genomics Awarded Patent for Innovative Cancer Test 2
(Date:7/31/2014)... -- Tandem Diabetes Care®, Inc. (NASDAQ: TNDM ), ... Pump, today reported its financial results for the quarter ended ... quarter of 2014 to the same period of 2013: ... million , t:slim Pump shipments grew 64 percent to ... months ended June 30, 2014 to the same period of ...
(Date:7/31/2014)... , July 31, 2014  Cepheid (NASDAQ: CPHD ... the following conferences, and invited investors to participate via webcast. ... New York, NY Wednesday, August 13, ... Health Care Conference, New York, NY ... Accessing Live Webcasts To access the live webcasts ...
(Date:7/31/2014)... , July 31, 2014   Auxilium Pharmaceuticals , ... specialty biopharmaceutical company, today announced that the Company will ... Thursday, August 7, 2014 before the opening of the ... conference call that day at 8:30 a.m. ET to ... 2014. The presentation slides to be used during the ...
Breaking Medicine Technology:Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 2Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 3Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 4Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 5Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 6Cepheid to Webcast Upcoming Financial Presentations 2Auxilium Pharmaceuticals, Inc. To Announce Second Quarter 2014 Results On August 7, 2014 2Auxilium Pharmaceuticals, Inc. To Announce Second Quarter 2014 Results On August 7, 2014 3
... III Study Provides Further Evidence of,the Significant ... Treatment,of Rheumatoid Arthritis, BASEL, Switzerland, June 6, ... multinational phase III Actemra,(tocilizumab) study, successfully reached ... proportion of patients treated with Actemra,in combination ...
... Topical Therapy Reduces TNF-alpha Production Through Inhibition,of ... 2007 /PRNewswire/ -- Anacor,Pharmaceuticals, a privately held ... placebo-controlled Phase 1 trial of,AN2728, a first-in-class ... psoriasis. The trial showed AN2728 to be,well-tolerated, ...
Cached Medicine Technology:New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 2New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 3New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 4Anacor Clinical Study of AN2728, a Novel Anti-Inflammatory,Compound, Shows Efficacy in Psoriasis 2
... a ubiquitous enzyme that catalyzes the ... also the specific protein that is ... (EMA) tests (Bio-Rad catalog number 29003 ... tests are highly sensitive and specific ...
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
We offer small and large pre-gelled Surface Electrodes suitable for EMG or EGG recordings....
Medicine Products: