Navigation Links
Improving recovery from spinal cord injury
Date:6/9/2010

. They then let the rats recover for another three weeks before assessing the degree of recovery.

Using a well-established, 21-point scale where zero represents paralysis and 21 is normal function, the team of researchers assesed treated and untreated rats for a range of functions including whether they could lift their feet off the ground and whether they had coordinated leg movements. The initial injury rendered all rats to score below four, and all rats, treated or not, recovered somewhat by the end of two weeks. By the end of five weeks after injury most untreated rats scored 12 or less, while most treated rats scored better than 15. "The difference in coordination control was most remarkable," says Schnaar.

In addition to motor control, spinal cord injury can cause other nervous system problems, including losing the ability to control blood pressure and heart rate. To see if sialidase treatment improved nerve connections enough to remedy these problems, the team measured the nerve circuits that control blood pressure in treated and untreated rats. They found that treated animals improved blood pressure control. "We interpret this as improved communication in the spinal cord," says Schnaar.

Finally, the team looked at the nerve ends under a microscope and found that indeed, treated nerves showed an increased number of "sprouted" nerve ends, which according to Schnaar, provided anatomical evidence to add to the functional evidence that "something is going on."

"The positive is that we have shown functional recovery in a relevant animal model of spinal cord injury," says Schnaar. "That being said, we haven't done full toxicity studies on these rats, which definitely needs to be done before we think about taking the long road into using this as a drug in people; efficacy in animals also doesn't necessarily translate to humans."


'/>"/>

Contact: Audrey Huang
audrey@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ACR task force makes recommendations for improving relationships between radiologists and hospitals
2. Report Finds Control of High Blood Pressure Improving
3. Improving the health of all the worlds children
4. Survival in metastatic breast cancer patients is improving: targeted therapies have contributed
5. Amistaff Launches RN Medical/Surgical & RN Pharmacology Exams Using New Validation Process Focused on Improving Quality of Patient Care
6. Health Occupations Students of America, Inc. and the U.S. Army Sign Memorandum of Understanding in Support of Improving Career Options for Nations Students
7. Care improving, cost saving Indiana Network for Patient Care expands
8. Improving care for low-birth-weight infants
9. Morehead Presents Webinar on "When Satisfaction Isn't Enough: Improving RN Engagement"
10. Global Hospitals and Healthcare Suppliers Focus on Cutting Costs and Improving Quality at 2010 GHX Supply Chain Summit
11. Charging less for more effective treatments could reduce health care costs while improving health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... York, NY (PRWEB) September 22, 2014 ... pain on the side of the hip , which ... bursitis treatment in Manhattan. This treatment is now offered at ... which is also called trochanteric bursitis, occurs when the ... a fluid-filled sac in the hip, between the iliotibial ...
(Date:9/22/2014)... The concept of a whole eye transplant seems ... grant from the U.S. Department of Defense, researchers ... Medicine hope to someday make implantation of an ... eye transplant could be a holy grail for ... of ophthalmology and grant co-recipient with colleagues at ...
(Date:9/22/2014)... New York, US (PRWEB) September 22, 2014 ... Heartbeat Experts’ perspectives on stakeholder management needs for the ... speak with Heartbeat Experts on stakeholder strategies for any ... clinically meaningful points of differentiation within an increasingly crowded ... , The impact of identifying community-based thought ...
(Date:9/22/2014)... Va. (PRWEB) September 22, 2014 ... the nation’s leading nonprofit authority on the ... healthcare information exchange, announced findings from its recent ... Health Plan Identifier (HPID) within electronic transactions adopted ... (HIPAA). WEDI conducted the survey from August 20 ...
(Date:9/22/2014)... CareFlight Air & Mobile Services ... a new AS365 N3+ Dauphin, the latest version of ... which is based at Miami Valley Hospital ... air medical transport helicopters. , “We have a lot ... Health Vice President, Emergency, Trauma, and CareFlight. “We’ve been ...
Breaking Medicine News(10 mins):Health News:DNR Clinic Offers Hip Bursitis Treatment in Manhattan 2Health News:DNR Clinic Offers Hip Bursitis Treatment in Manhattan 3Health News:Looking ahead: Whole eye transplant under development 2Health News:Download HeartBeat Experts White Paper: Stakeholder Management for new Prostate Cancer Products 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 2Health News:WEDI Announces Survey Results from Unique Health Plan Identifier (HPID) Industry Poll 3Health News:Miami Valley Hospital CareFlight begins Service with AS365 N3+ 2Health News:Miami Valley Hospital CareFlight begins Service with AS365 N3+ 3
... Centers for,Medicare & Medicaid Services (CMS) has selected the ... data analysis,services to detect potential fraud and waste in ... task order to help identify inappropriate,and unnecessary Medicaid payments ... MIP was created as a result of the federal ...
... MED, CEO DeCODE Genetics, WASHINGTON, June 5 ... Cardiovascular Institute:, Date: Thursday, June 12, 2008, ... 23rd Street, NW, Time: Noon - 2:50pm, ... Dr. Stefansson is CEO and co-founder of deCODE genetics ...
... MA Researchers from Boston University School of Medicine (BUSM) ... among Medicare beneficiaries at the end of life. The ... Internal Medicine. , According to researchers, medical treatments for ... year comprise almost 30 percent of Medicare expenditures. In ...
... Visit Denver to Rally Residents to Eat Right, Move More and ... Milk ... by the,ups and downs of different fad diets -- which seem to go ... been,slim. Two out of three Americans remain overweight or obese., A new ...
... and Indiana Fever for an evening of celebration, INDIANAPOLIS, ... will be honored by the March of Dimes on June ... collaboration to help families,with critically ill babies throughout the state ... walk., For several years, Anthem has teamed up with ...
... enable sexual maturity and fertility make a critical journey: from ... the brain. , They believe their studies in the ... neurons don,t make it and enable better ways to help ... "They can go to the right place but take too ...
Cached Medicine News:Health News:CMS Selects Thomson Reuters to Help Detect Medicaid Fraud in Eight States 2Health News:Genomics of Cardiovascular Disease: Current Clinical Applications 2Health News:Primary care visits reduce hospital utilization among Medicare beneficiaries at the end of life 2Health News:Message to Denver Residents: Forgo Fad Dieting and Join the Campaign for Healthy Weight 2Health News:Message to Denver Residents: Forgo Fad Dieting and Join the Campaign for Healthy Weight 3Health News:Message to Denver Residents: Forgo Fad Dieting and Join the Campaign for Healthy Weight 4Health News:Anthem Blue Cross and Blue Shield Honored by March of Dimes 2Health News:Zebrafish enable scientists to study the migration of neurons that enable sexual maturity 2Health News:Zebrafish enable scientists to study the migration of neurons that enable sexual maturity 3
(Date:9/22/2014)... NEW YORK , September 22, 2014 ... New Market Report on "Global Market Study on Ophthalmic ... Growth by 2020," the global ophthalmic devices market was valued at ... grow at a CAGR of 6.5% from 2014 to ... million in 2020. Browse the full Global Market ...
(Date:9/22/2014)...  Neuralstem, Inc. (NYSE MKT: CUR) announced that ... University, presented long-term follow up data on the Phase ... the treatment of amyotrophic lateral sclerosis (ALS or ... the Annual Symposium on ALS of the Foundation Andre-Delambre, ... and was not open to the public, covered data ...
(Date:9/22/2014)... PHOENIX , Sept. 22, 2014  For ... wrists, surgery often means facing the prospect of ... can be imagined, regular activities are also impacted, ... on the severity of the problem, some patients ... braces, which can even lead to permanent damage ...
Breaking Medicine Technology:Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 2Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 3Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 4Global Ophthalmic Devices Market will Reach $2,685.1 Million in 2020: Persistence Market Research 5Neuralstem ALS Investigator Presents Long-Term Follow Up Phase I Data 2Neuralstem ALS Investigator Presents Long-Term Follow Up Phase I Data 3Neuralstem ALS Investigator Presents Long-Term Follow Up Phase I Data 4Phoenix Arizona Hand Doctor Develops Revolutionary New Surgery System, Eliminates Need for Large Incisions 2
... (Nasdaq: BMRN ) today announced that Joshua Grass, ... a company update at the UBS Global Life Sciences Conference ... 3:30 p.m. ET.   Interested parties may access ... investor section of the BioMarin website, www.BMRN.com .  A ...
... Arcion Therapeutics , a venture backed clinical stage ... announced that the U.S. Food and Drug Administration (FDA) ... treatment of pain associated with Painful Diabetic Neuropathy (PDN). ... for topical administration. Arcion recently announced positive ...
Cached Medicine Technology:BioMarin to Present at the UBS Global Life Sciences Conference 2Arcion Therapeutics Receives FDA Fast Track Designation for ARC-4558 for the Treatment of Pain Associated with Painful Diabetic Neuropathy 2
... For enzyme immunoassays, designed to meet the ... and allows the user to run set ... The floating manifold on this strip washer ... at a time. Reliable, compact, and self-contained, ...
... available to handle multiple assays: ... Embla 384 Cell washer has ... optimized to avoid cell disturbance. ... and have been integrated with ...
... miniGene LW is a new plate washing system ... and 384 channel microplates with flat, V-shaped or ... 8 or 16 channel nozzle heads. Simple LCD ... An optional plate stacker is available for the ...
Space-saving counter top model,User initiated manual defrost,Standard features (see above),Internal freezing compartment,Removable half-shelf in refrigerator,Two shelves in door,UL 471 Commercial Ref...
Medicine Products: