Navigation Links
Improved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity
Date:5/23/2013

l in the L-DNR group vs. 75% in the idarubicin group). The probability of event-free survival (or pEFS) was also similar in the L-DNR (59%) and idarubicin groups (53%), as were pEFS results for standard risk (72% for L-DNR vs. 68% for idarubin) and high-risk patients (51% vs. 46%, respectively).

Overall, treatment with this intensified induction regimen had a similar safety and tolerability profile to the traditional idarubicin dose. Treatment-related mortality was lower in the L-DNR group than in the idarubicin group (2/257 vs. 10/264 patients), and there were no unusual or persistent toxicities seen when compared with previous related trials. The team observed generally low rates of cardiotoxicities across the treatment groups in the study, though fewer events were reported among the L-DNR treated patients than the idarubicin-treated patients. In the L-DNR group, there were four reports of severe acute cardiotoxicities, such as functional impairment, versus five events in the idarubicin group. There was a single patient reported to have late cardiotoxicity during follow-up in the L-DNR group, as compared with three patients in the idarubicin treatment group.

"These findings signal an important step forward in our goal to identify treatments that can give pediatric patients the best chance for long-term survival with minimal toxic side effects, and we believe the approach could have a number of extended applications. For example, this treatment formulation may be appropriate to use in adults or elderly patients to reduce the toxicity profile, or it may be of value for other malignant diseases in both children and adults," said Dr. Creutzig. "We look forward to further investigating L-DNR as the standard anthracycline induction treatment in future studies."


'/>"/>

Contact: Amanda Szabo
aszabo@hematology.org
202-552-4914
American Society of Hematology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers find genetic tie to improved survival time for pulmonary fibrosis
2. Irregular Menses and Pain Caused by Adenomyosis or Endometriosis Can Be Improved with Herbal Therapy without Pain Killers & Surgeries - Wuhan Dr. Lee’s TCM Clinic
3. hCGTreatments / Diet Doc hCG Diets & Weight Loss Offers improved hCG Diets With More Beneficial Nutritional Content, Possibly Offering Relief for Painful Symptoms of IBS
4. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Improved hCG Diet Helping Patient’s Control Eating Impulses
5. New FDA Proposed Tanning Bed Regulations Push For Improved Warnings During National Skin Cancer Awareness Month
6. hCGTreatments / Diet Doc hCG Diets and Weight Loss Plans Offers a New Solution To Shedding Excess Weight With Improved, Medically Supervised hCG Diet Plans
7. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Improved hCG Diets to Counteract Metabolic Slowdown
8. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers Improved hCG Diet Plans Capable of Relieving Migraine Headaches Associated with Carrying Extra Pounds
9. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Newly Improved hCG Diets for Healthy Lifestyle Changes without the Dangerous Risks of Weight Loss Surgery
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Targets America’s Teen Obesity Epidemic With Recently Improved hCG Diet Plans
11. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Combine Improved Prescription hCG with Lasting Education on How to Lose Weight Safely
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... September 18, 2014 According to a new ... Services Market - Global Industry Analysis, Size, Share, Growth, Trends ... services market was valued at USD 77607.7 million in 2013 ... from 2014 to 2020, to reach an estimated value of ... and services market is growing at a rapid pace due ...
(Date:9/18/2014)... September 18, 2014 The new ... boon to contractors and homeowners alike as it ... overtakes the home, causes potential health issues, and ... nationwide, the BuildClean system allows contractors to virtually ... and other standard remodeling tasks. , BuildClean removes ...
(Date:9/18/2014)... T-System Inc. today announced Holyoke Medical ... — EV™ for physicians — improving ... best-of-breed solutions, Holyoke chose T-System’s solution because not ... and reimbursement, but also its ability to integrate ... used to capture emergency department, (ED) nurse documentation. ...
(Date:9/18/2014)... the popular online supplier of funny figurines, has added a ... line. Moreover, all the company’s products are now offered with ... special offer before September 29, 2014. Customers who place bulk ... bobblehead doll ). , “We are pleased to ... make our interesting items available to all the global customers. ...
(Date:9/18/2014)... How much is a serving? , Most ... to the obesity epidemic in the United States. ... to manage portion size during the next “Healthy Eating ... House, 755 Ohltown Road, Austintown. , Registered dietician and ... and answer questions from 12:30 to 2 p.m. Oct. ...
Breaking Medicine News(10 mins):Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 3Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 4Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 2Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 3Health News:New BuildClean™ System Brings Livability Back to Home Remodeling 4Health News:Holyoke Medical Center ER Improves Productivity and Reimbursement with T-System 2Health News:Discounted Custom Bobbleheads Online For Sale At WowBobble.com 2Health News:HMHP Workshop Addresses Portion Control 2
... N.Y. study finds that weather warmer than 75 degrees poses ... research suggests that cocaine overdose deaths in New York City ... average weekly temperature goes past 75 degrees Fahrenheit. , ... Addiction , are based on death statistics in the city ...
... Researchers say defibrillators can be turned off on admission, ... care for people who are dying often forget to ... research has found. , Only 20 percent of more ... that they had a question on their admitting form ...
... , ... ... ... ...
... ... ... , ... , , , ...
... new study, led by researchers at the Herbert Irving ... demonstrates that acupuncture may be an effective therapy for ... are being treated with commonly used hormonal therapies. Results ... . Joint pain and stiffness are common side ...
... it possible to build supercomputers that can replicate the ... to an implantable chip for interfacing with neurons and ... nanoscience and neuroscience are now advancing each other in ... what this means was the topic of an hour-long ...
Cached Medicine News:Health News:Hearts of Hospice Patients Being Needlessly Shocked 2Health News:Hearts of Hospice Patients Being Needlessly Shocked 3Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 2Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 3Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 2Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 3Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 4Health News:Healthcare Trust of America, Inc. Acquires an 80,562 Square Foot Medical Office Portfolio Located in Atlanta, Georgia for $19,550,000 5Health News:Acupuncture may relieve joint pain caused by some breast cancer treatments 2
(Date:9/18/2014)... 18, 2014  ADM Tronics Unlimited, Inc. (OTCQB: ... to its corporate Advisory Board for business development. ... the Harvard Medical School and Visiting Professor at ... his Masters degree in Electronics Engineering and his ... of Bologna. After spending a year as a ...
(Date:9/18/2014)... 18, 2014  ePharmaSolutions, the leading provider ... the Disruptive Innovator of the Year at ... platform. This solution includes an integrated clinical ... (eTMF), a remote monitoring application, eSource and ... screening and matching technology. The ...
(Date:9/18/2014)... , Sept. 18, 2014  Zacks.com announces the ... day the Zacks Equity Research analysts discuss the latest ... Stocks recently featured in the blog include the Avanir Pharmaceuticals ... (Nasdaq: NPSP - Free Report ), Orexigen (Nasdaq: ... MDVN - Free Report ) and Gilead (Nasdaq: ...
Breaking Medicine Technology:ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 2ADM Tronics Appoints Gianluca DeNovi, Ph.D. To Advisory Board 3ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 2ePharmaSolutions Named 2014 Disruptive Innovator of the Year for its ePharmaONE eClinical Platform 3The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 2The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 3The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 4The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 5The Zacks Analyst Blog Highlights: Avanir Pharmaceuticals, NPS Pharmaceuticals, Orexigen, Medivation and Gilead 6
... United Arab Emirates, Sept. 22 NewBridge Pharmaceuticals announced ... agreement with Orexo AB (STO: ORX) that grants NewBridge ... treatment of breakthrough cancer pain, in the Middle East ... and sell the product in these territories.  The agreement ...
... Decision Resources, one of the world,s leading research and ... to generic erosion of key agents, the colorectal cancer drug ... from more than $6.4 billion in 2009 to just under ... Italy, Spain, United Kingdom and Japan. The Pharmacor ...
Cached Medicine Technology:NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 2NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 3NewBridge Pharmaceuticals Signs Agreement for Abstral™ for the Middle East and Africa 4Owing to Generic Erosion of Key Agents, the Colorectal Cancer Drug Market Will Remain Relatively Flat Through 2019 2Owing to Generic Erosion of Key Agents, the Colorectal Cancer Drug Market Will Remain Relatively Flat Through 2019 3
Daubenspeck sharp curette, 8....
Bruns bone curette, 9, oval, solid actagonal handle....
MRI curette, 8.5" overall length....
15" overall length, 5" handle....
Medicine Products: