Navigation Links
Improved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity
Date:5/23/2013

(WASHINGTON, May 23, 2013) Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

Acute myeloid leukemia (AML), the second most common form of leukemia in children, is a blood cancer in which the bone marrow makes a large number of abnormal white blood cells that crowd out other healthy blood cells over time, leading to infection, anemia, or excessive bleeding. Most adults and children with AML receive a first line of treatment (known as induction therapy) soon after diagnosis with a class of chemotherapy drugs called anthracyclines. Standard induction regimens in children typically consist of three days of an anthracycline such as daunorubicin or idarubicin and seven to 10 days of another chemotherapy such as cytarabine. Approximately 60 to 70 percent of children with AML achieve long-term survival with this combination of drugs.

Recent evidence has suggested that increasing the intensity of induction treatment might improve remission rates and perhaps overall survival in AML patients. However, clinicians have used this approach sparingly in pediatric patients because of documented dose-related anthracycline toxicity in children, particularly the significant risk of damage to the developing heart muscle. In an effort to increase the effectiveness of this treatment for children with AML but reduce the cardiac risk profile, researchers are now investigating a liposomal (or lipid-based) formulation of the anthracycline daunorubicin (L-
'/>"/>

Contact: Amanda Szabo
aszabo@hematology.org
202-552-4914
American Society of Hematology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers find genetic tie to improved survival time for pulmonary fibrosis
2. Irregular Menses and Pain Caused by Adenomyosis or Endometriosis Can Be Improved with Herbal Therapy without Pain Killers & Surgeries - Wuhan Dr. Lee’s TCM Clinic
3. hCGTreatments / Diet Doc hCG Diets & Weight Loss Offers improved hCG Diets With More Beneficial Nutritional Content, Possibly Offering Relief for Painful Symptoms of IBS
4. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Improved hCG Diet Helping Patient’s Control Eating Impulses
5. New FDA Proposed Tanning Bed Regulations Push For Improved Warnings During National Skin Cancer Awareness Month
6. hCGTreatments / Diet Doc hCG Diets and Weight Loss Plans Offers a New Solution To Shedding Excess Weight With Improved, Medically Supervised hCG Diet Plans
7. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Improved hCG Diets to Counteract Metabolic Slowdown
8. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers Improved hCG Diet Plans Capable of Relieving Migraine Headaches Associated with Carrying Extra Pounds
9. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Newly Improved hCG Diets for Healthy Lifestyle Changes without the Dangerous Risks of Weight Loss Surgery
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Targets America’s Teen Obesity Epidemic With Recently Improved hCG Diet Plans
11. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Combine Improved Prescription hCG with Lasting Education on How to Lose Weight Safely
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2015)... China (PRWEB) April 28, 2015 Georgia ... major municipalities in China that will partner with the ... reduce smoking in a nation that produces more tobacco ... world. , The project, China Tobacco Control Partnership-Tobacco Free ... leaders have shown willingness to support tobacco control efforts ...
(Date:4/28/2015)... Missouri (PRWEB) April 28, 2015 ... to healthcare executive search, announced today that it has ... & Chief Operating Officer search for The ... , Reporting to QHS President & CEO Arthur ... Officer will have operating responsibility for the Queen’s Medical ...
(Date:4/28/2015)... April 28, 2015 Georgia Partnership ... establishment of telemedicine programs in communities throughout Georgia, announces ... selected as speakers at the American Telemedicine Association ... 2015, in Los Angeles, CA. , GPT’s roster ... Sherrie Williams, Executive Director; Loren Nix, Liaison; and board ...
(Date:4/28/2015)... April 28, 2015 Researchers from four ... dose of a steroid prior to pemetrexed (Alimta) chemotherapy ... reaction. Click here to read the full story ... from the Raabe College of Pharmacy in Ohio, Stanford ... Appalachian Regional Healthcare in Kentucky gave a single dose ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 Dead or damaged ... and their property. In many cases, tree removal by a ... way to eliminate the threat. , In their ... of tree removal available to property owners today. Each method ... for a job well done. , The article states that, ...
Breaking Medicine News(10 mins):Health News:Georgia State Names Partner Cities For Tobacco Control Project 2Health News:The Queen’s Health Systems Retains MSA Executive Search to Recruit Executive Vice President & Chief Operating Officer 2Health News:Georgia Partnership for TeleHealth Team Selected to Present at ATA 2015 2Health News:Study Finds New Regimen May Ward Off Skin Rash from Common Mesothelioma Drug, According to Surviving Mesothelioma 2Health News:Tree Removal Methods and Services Discussed in Recent Article by Precision Tree Services 2
... Crestor worked well in those with normal LDL but ... 9 (HealthDay News) -- A widely used cholesterol-lowering drug ... adverse outcomes in people who do not ... Crestor (rosuvastatin), did have high levels of C-reactive protein ...
... LAFAYETTE HILL, Pa., Nov. 9 The NHS Human,Services ... on November,8, 2008 at the Hyatt Regency Penn,s Landing ... for the Foundation, which supports the mission,of NHS Human ... human,services in the country., Every year the Foundation ...
... time to change their Medicare Part D Prescription Drug Coverage begins November ... they so choose, this time period is also an opportunity for people ... , ... Washington (PRWEB) November 9, 2008 -- The National Council on Aging ...
... Glaucoma-related highlights of today,s scientific program of the 2008 ... and European Society of Ophthalmology (SOE) include a study ... carotid artery narrowing and potentially elevated risk for stroke, ... of fasting, common to the world,s seven major religions, ...
... a risk factor for high blood pressure, low levels ... as high levels of sodiumespecially among African Americans, according ... Nephrology,s 41st Annual Meeting and Scientific Exposition in Philadelphia, ... about lowering salt or sodium in the diet in ...
... patients in need of organ transplants on the rise, ... sources for organs. Individuals are willing to donate their ... the poverty rate is high, resulting in numerous reports ... troubling issue will be the topic of a session ...
Cached Medicine News:Health News:Statin Might Help More People Fight Heart Disease Than Thought 2Health News:Statin Might Help More People Fight Heart Disease Than Thought 3Health News:Gala Raises Funds for NHS Human Services 2Health News:Attention Seniors: Plans Change. Your Needs Change. Shop and Compare Your Prescription Drug Coverage Now 2Health News:Attention Seniors: Plans Change. Your Needs Change. Shop and Compare Your Prescription Drug Coverage Now 3Health News:Attention Seniors: Plans Change. Your Needs Change. Shop and Compare Your Prescription Drug Coverage Now 4Health News:AAO-SOE Joint Meeting Nov. 9 glaucoma research highlights 2Health News:AAO-SOE Joint Meeting Nov. 9 glaucoma research highlights 3Health News:AAO-SOE Joint Meeting Nov. 9 glaucoma research highlights 4Health News:Low potassium linked to high blood pressure 2Health News:Transplant experts convene at ASN Renal Week 2008 to discuss organ trafficking 2
(Date:4/28/2015)... 2015  Rosa & Co. LLC, a drug development ... today announced its pleasure to be lead partner for ... Systems Pharmacology (QSP). The conference focuses on uses and ... Logo - ... Rosa,s lead sponsorship is the second of ...
(Date:4/28/2015)... , April 28, 2015  BioDelivery Sciences International, ... Sarah DeRossett , MD, PhD to the position ... Affairs.  Dr. DeRossett joins BDSI with nearly twenty-five ... the neurosciences area.  Dr. DeRossett will oversee clinical ... well as the medical support for BDSI,s currently ...
(Date:4/27/2015)... China , April 27, 2015 Techpool Bio-Pharma ... under the leadership of its new chief executive officer, transforming ... Before Henry Lee took office in ... in the pharmaceutical field, including Novartis and Eisai, with more ... China and the Asia-Pacific ...
Breaking Medicine Technology:Rosa & Co. is the Lead Partner for the Quantitative Systems Pharmacology (QSP) Congress in Basel, Switzerland and Will Present the Keynote Address 2Rosa & Co. is the Lead Partner for the Quantitative Systems Pharmacology (QSP) Congress in Basel, Switzerland and Will Present the Keynote Address 3BioDelivery Sciences Appoints Dr. Sarah DeRossett to Vice President of Clinical Research and Medical Affairs 2BioDelivery Sciences Appoints Dr. Sarah DeRossett to Vice President of Clinical Research and Medical Affairs 3BioDelivery Sciences Appoints Dr. Sarah DeRossett to Vice President of Clinical Research and Medical Affairs 4Techpool Transforms Into International Player 2Techpool Transforms Into International Player 3
... Jan. 3, 2012 Reportlinker.com announces that ... in its catalogue: Transdermal ... http://www.reportlinker.com/p0203552/Transdermal-Drug-Delivery---Technologies-Markets-and-Companies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology ... -Up-to-date one-stop information on transdermal ...
... 3, 2012  When the FDA removed Fen-Phen from the U.S. ... that powerful diet pills had become a thing of the ... burners sprung up almost immediately, and it wasn,t long before ... bags and medicine cabinets. Demand for these ...
Cached Medicine Technology:Transdermal Drug Delivery - Technologies, Markets, and Companies 2Transdermal Drug Delivery - Technologies, Markets, and Companies 3Transdermal Drug Delivery - Technologies, Markets, and Companies 4Transdermal Drug Delivery - Technologies, Markets, and Companies 5Transdermal Drug Delivery - Technologies, Markets, and Companies 6Transdermal Drug Delivery - Technologies, Markets, and Companies 7Transdermal Drug Delivery - Technologies, Markets, and Companies 8Transdermal Drug Delivery - Technologies, Markets, and Companies 9Transdermal Drug Delivery - Technologies, Markets, and Companies 10Transdermal Drug Delivery - Technologies, Markets, and Companies 11BiphedAdrene™, Complex Phenylethylamine Provisional Plus Aggressive Thermogenic Compound, Leads Super-Powerful "Diet Pill" Comeback 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: