Navigation Links
Improved chemo regimen for childhood leukemia may offer high survival, no added heart toxicity
Date:5/23/2013

(WASHINGTON, May 23, 2013) Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

Acute myeloid leukemia (AML), the second most common form of leukemia in children, is a blood cancer in which the bone marrow makes a large number of abnormal white blood cells that crowd out other healthy blood cells over time, leading to infection, anemia, or excessive bleeding. Most adults and children with AML receive a first line of treatment (known as induction therapy) soon after diagnosis with a class of chemotherapy drugs called anthracyclines. Standard induction regimens in children typically consist of three days of an anthracycline such as daunorubicin or idarubicin and seven to 10 days of another chemotherapy such as cytarabine. Approximately 60 to 70 percent of children with AML achieve long-term survival with this combination of drugs.

Recent evidence has suggested that increasing the intensity of induction treatment might improve remission rates and perhaps overall survival in AML patients. However, clinicians have used this approach sparingly in pediatric patients because of documented dose-related anthracycline toxicity in children, particularly the significant risk of damage to the developing heart muscle. In an effort to increase the effectiveness of this treatment for children with AML but reduce the cardiac risk profile, researchers are now investigating a liposomal (or lipid-based) formulation of the anthracycline daunorubicin (L-
'/>"/>

Contact: Amanda Szabo
aszabo@hematology.org
202-552-4914
American Society of Hematology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers find genetic tie to improved survival time for pulmonary fibrosis
2. Irregular Menses and Pain Caused by Adenomyosis or Endometriosis Can Be Improved with Herbal Therapy without Pain Killers & Surgeries - Wuhan Dr. Lee’s TCM Clinic
3. hCGTreatments / Diet Doc hCG Diets & Weight Loss Offers improved hCG Diets With More Beneficial Nutritional Content, Possibly Offering Relief for Painful Symptoms of IBS
4. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Improved hCG Diet Helping Patient’s Control Eating Impulses
5. New FDA Proposed Tanning Bed Regulations Push For Improved Warnings During National Skin Cancer Awareness Month
6. hCGTreatments / Diet Doc hCG Diets and Weight Loss Plans Offers a New Solution To Shedding Excess Weight With Improved, Medically Supervised hCG Diet Plans
7. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Improved hCG Diets to Counteract Metabolic Slowdown
8. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers Improved hCG Diet Plans Capable of Relieving Migraine Headaches Associated with Carrying Extra Pounds
9. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Newly Improved hCG Diets for Healthy Lifestyle Changes without the Dangerous Risks of Weight Loss Surgery
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Targets America’s Teen Obesity Epidemic With Recently Improved hCG Diet Plans
11. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Combine Improved Prescription hCG with Lasting Education on How to Lose Weight Safely
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... , , , , ... , , , , ... 50m downrange from the firer and approximately 30cm from the bullet... , , ... , , , , , ... , , , , , , University of Southampton researchers, ...
(Date:7/9/2014)... School of Medicine of the University of Southern ... specific component of the immune system are completely ... infection. The discovery suggests that blocking this immune ... autoimmune and hyper-inflammatory diseases such as rheumatoid arthritis ... published online on June 23 in The ...
(Date:7/8/2014)... Department of Defense,s Defense Advanced Research Projects Agency ... to $2.5 million to develop an implantable neural ... neurons within the brain to help restore memory, ... builds on the understanding that memory is a ... the brain encode information, store it and retrieve ...
(Date:7/8/2014)... 2014 In a study published yesterday in the ... La Jolla Institute (LJI) led by Pandurangan Vijayanand, Ph.D. identify ... currently affects over 200 million people world wide. , ... be divided into small sections or ,neighborhoods., Scientists can ... primed for gene production, by looking for a marker on ...
(Date:7/8/2014)... new NPR/Robert Wood Johnson Foundation/Harvard School of Public Health ... stress in Americans, lives finds that about half of ... stressful event or experience in the past year. Nearly ... to health. , More than half of those who ... month say too many overall responsibilities and financial problems ...
Breaking Medicine News(10 mins):Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 2Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 3Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 4Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 5Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 6Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 7Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 2Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 3Health News:LJI develops new approach to identify genes poised to respond in asthma patients 2Health News:Poll finds health most common major stressful event in Americans' lives last year 2Health News:Poll finds health most common major stressful event in Americans' lives last year 3Health News:Poll finds health most common major stressful event in Americans' lives last year 4
... ... international events for Valentine,s weekend in Las Vegas: The USA ... the Power Pilates "Power Higher" Conference will host Pilates professionals worldwide. ... teams, Pilates professionals and thousands of spectators from around the world ...
... from the Cleveland Clinic found that the overall mortality ... rheumatic diseases was not worse than the age and ... reported in previous studies of rheumatic diseases and conditions ... study appear in the February issue of Arthritis ...
... , Jan. 27 Ms. Lorren ... issued the following statement in advance of the President,s ... more than 150 public, private, and voluntary organizations dedicated to ... viral hepatitis that afflicts more than 5 million Americans: , ...
... had brain or other central nervous system cancers, or ... public, according to an article published online January 27 ... . This study was undertaken because previous studies ... had contradictory findings, or were not population-based. E.R. ...
... from diabetes, according to a prospective study of Group ... kidney failure or blindness, the result of small vessel ... heart attack or stroke. The findings were published ... journal of the American Diabetes Association. The study was ...
... Study suggests higher cost-sharing for outpatient visits may increase ... Boosting co-pays for doctor visits and other outpatient care ... may have the unintended consequence of sharply increasing hospitalizations, ... end up inflating overall health-care spending and put vulnerable ...
Cached Medicine News:Health News:Rugby & Pilates Have a Date for Valentine's Weekend in Vegas 2Health News:Rugby & Pilates Have a Date for Valentine's Weekend in Vegas 3Health News:Rugby & Pilates Have a Date for Valentine's Weekend in Vegas 4Health News:Rugby & Pilates Have a Date for Valentine's Weekend in Vegas 5Health News:Mortality rates for pediatric rheumatology patients significantly lower than previously reported 2Health News:NVHR Issues Challenge to Administration, Congress: Don't Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze 2Health News:NVHR Issues Challenge to Administration, Congress: Don't Leave 5 Million Americans Afflicted with Chronic Viral Hepatitis Out in the Cold with Budget Freeze 3Health News:Severe complications of diabetes higher in depressed patients 2Health News:Raising Co-Pays for Doctor Visits Raises Seniors' Hospital Use 2Health News:Raising Co-Pays for Doctor Visits Raises Seniors' Hospital Use 3
(Date:1/15/2014)... LAVAL, Quebec , Jan. 15, 2014  Valeant Pharmaceuticals ... VRX) announced that the applicable waiting period under the ... to the previously announced tender offer by its indirect ... the outstanding shares of common stock of Solta Medical, ...
(Date:1/14/2014)... 14, 2014 HeartWare International, Inc . (NASDAQ: ... invasive, miniaturized circulatory support technologies that are revolutionizing the ... expects revenues for the fourth quarter of 2013 will ... to approximately $208 million. "Our full-year revenue ...
(Date:1/14/2014)... Jan. 14, 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC Screw ... with accompanying instrumentation to place and insert the screw ... soft tissue (e.g. ligament) repair or reconstruction as it ... (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) ...
Breaking Medicine Technology:Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 2HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 4Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3
... Panasonic Healthcare Group today announced a new distribution ... for the hearing professional, which will allow licensed ... www.panasonic-hearingshop.com .  This is the first time ... for hearing care professionals to order online.    ...
... CHICAGO, Feb. 10, 2012  Zacks highlights commentary from People and ... http://photos.prnewswire.com/prnh/20101027/ZIRLOGO ) For more Voice of the ... Market Percolates, Doubters Wait They,re ... of course the troll community. They,re telling you the market ...
Cached Medicine Technology:Panasonic Reaches Distribution Agreement With The Hearing Shop 2Panasonic Reaches Distribution Agreement With The Hearing Shop 3Panasonic Reaches Distribution Agreement With The Hearing Shop 4Zacks' Voice of the People highlights opportunities with Walgreen, Occidental Petroleum and Brown & Brown 2Zacks' Voice of the People highlights opportunities with Walgreen, Occidental Petroleum and Brown & Brown 3
The BluefishRx ICD-9 is a Palm OS code lookup tool which incorporates the ICD-9 code set with the full and short code descriptions. It includes a multi keyword search tool with a dictionary of over 2...
MD Coder v 6.0 is a charge capture for the Palm OS and Pocket PC operating systems. We have integrated the feedback from hospitals and physicians. MD Coder v 6.0 comes in three versions: Physician Ba...
Preferred Health Resourses Practice Management System is called Remedy. The PDA version is Remedy for the Palm. It is a data capture program for your medical billing....
ZapICD is a reference to the complete set of ICD codes....
Medicine Products: