Navigation Links
Improved cancer treatments the focus of $6 milion research project

Research into the natural process of cell death, its role in the development of blood cancers and harnessing cell death to improve cancer therapies has seen a Walter and Eliza Hall Institute research team from Melbourne, Australia, awarded a grant of more than $6 million by the US-based Leukemia & Lymphoma Society.

The grant of $1.25 million a year for five years was one of four awarded through the Leukemia & Lymphoma Society's Specialized Center of Research (SCOR) program.

The Walter and Eliza Hall Institute team was the only team outside the United States awarded a SCOR program grant.

Professor Jerry Adams, director of the SCOR program and joint head of the Institute's Molecular Genetics of Cancer division, said the research team had been investigating apoptosis, the natural process of cell death, for more than two decades.

"Our bodies make billions of blood cells every day, and, to make room, billions of other blood cells must undergo apoptosis," Professor Adams said. "If some cells fail to die when they should, they can develop into leukaemia, lymphoma or multiple myeloma. We are studying how impaired apoptosis contributes to the development of blood cell cancers and renders the malignant cells more resistant to current therapies."

In the late 1980s and early 1990s, institute researchers discovered that the Bcl-2 protein family promoted the development of blood cancers by preventing the death of cancerous cells and also helped cancer cells resist anti-cancer therapies. This put apoptosis centre stage in cancer research.

"Nearly all anti-cancer therapies act through the Bcl-2 apoptotic switch," Professor Adams said, "but they affect it indirectly. To improve cancer treatments we are investigating the effectiveness of new drugs, used either alone or in combination with other therapies, that directly engage the apoptotic machinery and flip the cell death switch. We have already identified some promising drug candidates and this new funding will allow us to further investigate their effectiveness and the usefulness of other new anti-cancer agents."

Contact: Ms. Penny Fannin
Walter and Eliza Hall Institute

Related medicine news :

1. 30-day mortality after AMI drops with improved treatment
2. PSA Testing Linked to Improved Prostate Cancer Survival
3. Prostate cancer survival rates improved since introduction of PSA testing
4. East meets West to bring improved sanitation and hygiene practices to Vietnam, Cambodia
5. By studying animal health, researchers find improved ways for developing, testing cancer therapies
6. Health care organizations quest for reduced costs and improved quality
7. HCOs find risks & opportunities in quest for reduced costs & improved quality
8. Is Improved Vaccine Causing Whooping Cough Outbreaks?
9. Expanding Medicaid to low-income adults leads to improved health, fewer deaths
10. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
11. PaleoMeal Organic Whey Protein Formula Improved According to Rockwell Nutrition
Post Your Comments:
Related Image:
Improved cancer treatments the focus of $6 milion research project
(Date:10/13/2015)... ... 13, 2015 , ... PhyMed Healthcare Group , a ... partnership with WPC Healthcare , a provider of predictive analytics solutions for ... into an aggregated data repository necessary to perform reporting and analytics on selected ...
(Date:10/13/2015)... , ... October 13, 2015 , ... ... solutions, announced today their sponsorship of the Microsoft Dynamics AXUG, GPUG and NAVUG ... Summit, GPUG Summit and NAVUG Summit are independent user conferences designed and led ...
(Date:10/13/2015)... Radnor, Pennsylvania (PRWEB) , ... October 13, 2015 ... ... and people through a unique private messaging application, announced today a significant contract ... for another five years. Independence plans to build on the growing success of ...
(Date:10/13/2015)... ... October 13, 2015 , ... A child without a healthy ... SmileCareClub , the leading remote invisible aligner system, has joined with Global Dental ... without it. For each aligner treatment plan purchased, SmileCareClub will donate one clinic visit ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... a first-of-its kind product that targets the unique health needs of new ... the American Pregnancy Association ( ), utilizes Nordic Naturals’ exclusive, new, ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)...  A minimally-invasive treatment just became available to men ... more than 10 years of clinical trials, the Food ... of High Intensity Focused Ultrasound (HIFU), a procedure that ... tissue and minimizing chances for erectile and urinary dysfunction ... a pioneering Miami urologist who ...
(Date:10/13/2015)... ALEXANDRIA, Va. , Oct. 13, 2015 /PRNewswire-USNewswire/ ... Pharmacists Association,s (NCPA) Digest , sponsored by ... to prescription medication and more diversified pharmacy revenue ... independent community pharmacies. NCPA Digest ... to patients and particularly those in underserved inner ...
(Date:10/13/2015)... , Oct. 13, 2015  Human Longevity, Inc. ... practice of medicine, announced today the launch of the ... project that has the potential to transform healthcare. The ... Diego, CA , at HLI,s headquarters facility. More ... in other US and International cities. ...
Breaking Medicine Technology: