Navigation Links
Important Data Presented on Independent Predictors of Mortality in Patients With Idiopathic Pulmonary Fibrosis
Date:5/17/2009

consistent with previous studies, the most frequently reported side effects were gastrointestinal symptoms and rash.

An exploratory analysis of pooled data from both trials revealed that treatment with pirfenidone resulted in a 30% relative reduction in the percentage of patients who experienced an absolute decline in percent predicted FVC of at least 10%. This magnitude of decline is considered clinically meaningful as a decline in percent predicted FVC as small as 5% over a six-month period has been shown to be an independent predictor of mortality in patients with IPF, as reported in the du Bois presentation at ATS.

InterMune expects to submit a new drug application (NDA) to the FDA in the summer of 2009 and a marketing authorization application (MAA) to the European authorities around the end of 2009.

About IPF

Idiopathic pulmonary fibrosis (IPF) is a disabling and ultimately fatal disease that affects a total of approximately 200,000 people in the United States and Europe, with approximately 30,000 new cases developing in the United States alone, each year. There are no medicines approved by the U.S. Food and Drug Administration (FDA) or European Medicines Evaluation Agency (EMEA) for the treatment of IPF. On October 16, 2008, pirfenidone was approved for marketing in Japan as Pirespa(R), the first regulatory approval of any treatment for IPF in any major market in the world. IPF is characterized by inflammation and scarring (fibrosis) in the lungs, hindering the ability to process oxygen and causing shortness of breath (dyspnea) and cough. IPF is a progressive disease, meaning that over time, lung scarring and symptoms increase in severity. The median survival time from diagnosis is two to five years.

About Pirfenidone

Prior in-vitro evidence has shown that pirfenidone inhibits collagen synthesis, down-regulates profibrotic cytokines and decreas
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6

Related medicine news :

1. CMSA Delivers Important Message to Congress: Case Management Services Improve Patient Care and Should Be Key Strategy in Health Care Reform Initiatives
2. What Motivates Physicians to Succeed? Money Isn't Most Important
3. Major statin study reveals several important findings for reducing prostate cancer and disease
4. Leapfrog Group Hospital Survey Finds Majority of Hospitals Fail to Meet Important Quality Standards
5. New Research Shows Tree Nuts May Play an Important Role in the Health of People With Diabetes
6. UT Southwestern researchers reveal how the brain processes important information
7. Nu Skin Charitable Promotion Reaches Important Milestone: 100,000 Trees Donated to African Nation of Malawi
8. AUDIO from Medialink and Mens Health Network: Important Decision Regarding Prostate Cancer
9. Penn researchers identify new protein important in breast cancer genes role in DNA repair
10. Important new model shows how proteins find the right DNA sequences
11. Why Blood and Bone Marrow Donors Are So Important: Extreme Makeover: Home Edition Profiles Blood Drive Honoree Lizzie Bell
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... A medical malpractice case which was filed ... by Lori Mandel, an office manager in her 50’s, ... Ms. Mandel sought the medical expertise of an ... that affected the quality of her life and her ... that her doctor rendered conservative treatment for 2 years, ...
(Date:5/23/2013)... International Science Consortium, Ltd., issued the following statement ... 2013: , Reform of chemical safety legislation will ... , Ensuring the safety and appropriate use ... the EPA,s Toxic Substances Control Act is a ... vision for transforming toxicity testing "from a system ...
(Date:5/23/2013)... in imaging of brain activity developed by Jean ... and his colleagues lead to improved treatment of ... electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI) ... generating epileptic seizures, giving neurosurgeons a better understanding ... These results were presented at the 2013 ...
(Date:5/23/2013)... Bronson Gray HealthDay Reporter , , WEDNESDAY, May 22 ... device used to save an infant born with a serious ... marriage of bioengineering and surgery. A report in the ... the situation that sparked the innovation. At first, the ... began to have difficulty breathing and eating when he was ...
(Date:5/23/2013)... According to a new market report "Service Delivery ... Management (SDM); Telecom Application Server; Service Creation Environment; Orchestration ... published by MarketsandMarkets, the SDP Market is expected to ... 9.15% from 2013 to 2018. , Browse:, ... 84 Figures , 189 Pages and an ...
Breaking Medicine News(10 mins):Health News:New York Law Journal Releases Top Medical Malpractice Case for 2012: NY Supreme Court Awards $8.6 Million to Plaintiff after Doctor's Misdiagnosis Led to Personal Injury 2Health News:New York Law Journal Releases Top Medical Malpractice Case for 2012: NY Supreme Court Awards $8.6 Million to Plaintiff after Doctor's Misdiagnosis Led to Personal Injury 3Health News:New imaging techniques used to help patients suffering from epilepsy 2Health News:Docs Use 3-D Printer to Create Lifesaving Airway Device for Infant 2Health News:Docs Use 3-D Printer to Create Lifesaving Airway Device for Infant 3Health News:Service Delivery Platform (SDP) Market Is Growing at a CAGR of 9.15% & to Reach $6.94 Billion by 2018 - New Report by MarketsandMarkets 2Health News:Service Delivery Platform (SDP) Market Is Growing at a CAGR of 9.15% & to Reach $6.94 Billion by 2018 - New Report by MarketsandMarkets 3
... , ENGLEWOOD, Colo., Aug. 10 Baxa, ... and administration of fluid medications, announces the launch of a ... and medication safety practices. The Culture of Safety Page, ... share experiences, insights and ideas for improving their profession and ...
... Aug. 10 /PRNewswire-Asia/ -- China Medicine Corporation,(OTC Bulletin ... leading,developer and distributor of prescription and over the ... supplements, and,medical devices and medical formulations, today announced ... a.m. Eastern Time on Thursday, August 13, 2009, ...
... , SAN FRANCISCO, Aug. 10 ... Mark Gastineau to senior vice president and chief executive of ... Unit (ISGBU). Gastineau joined Blue Shield in 2006 as ... underwriting and compliance areas in developing strategies to increase membership ...
... ... and school administrators will help U.S. schools meet growing needs of students with autism ... ... Society announced the publication of professional competencies for teaching students with autism spectrum disorders ...
... , , NEW YORK, Aug. 10 ... letter of intent to form ZiRx Therapeutics, Ltd., a joint venture that ... cell proteins with drugs that potentially block or stop the spread of ... to broad spectrum antiviral drugs as well as drugs that are less ...
... YORK, Aug. 10 In an unprecedented meeting at the UN, ... and currently an opposition leader and human rights protagonist for Iran, ... violations of human rights by the regime in Iran. , ... Secretary General for his June 22 statement of urgent concern over ...
Cached Medicine News:Health News:Baxa Corporation Launches 'Culture of Safety' Facebook Page 2Health News:Baxa Corporation Launches 'Culture of Safety' Facebook Page 3Health News:China Medicine Announces Conference Call to Discuss Second Quarter 2009 Results 2Health News:Mark Gastineau Named Senior Vice President of Individual, Small Group, and Government Business Unit at Blue Shield of California 2Health News:New National Professional Competencies for Teachers of Autism Released by Leaders in the Field 2Health News:New National Professional Competencies for Teachers of Autism Released by Leaders in the Field 3Health News:Rx for Africa, Inc. and Zirus, Inc. Create Joint Venture, ZiRx Therapeutics, Ltd. 2Health News:Rx for Africa, Inc. and Zirus, Inc. Create Joint Venture, ZiRx Therapeutics, Ltd. 3Health News:Former UN Human Rights Rapporteur Offers 7 Points of Action on Iran to the UN Secretary General 2
(Date:5/23/2013)... , May 23, 2013  Hologic, Inc. ... ), a leading developer, manufacturer and supplier of ... with an emphasis on serving the healthcare needs ... observational study in a U.S. clinical practice comparing ... (breast tomosynthesis) with conventional 2D mammography alone showed ...
(Date:5/23/2013)... , May 23, 2013  Spring Bank Pharmaceuticals, ... treatment of viral infections, today announced that it has ... 9200, its investigational, once daily, oral therapy for the ... healthy, HCV-infected patients and is designed to assess both ... 9200 is a first-in-class drug for the treatment of ...
(Date:5/23/2013)... 2013   Direct to implant, or "one ... appropriate option for many women with BRCA (BReast ... breast cancer risk, or with breast cancer. Traditionally, ... a second surgery to insert permanent implants, but ... as mastectomy can be a medically and cosmetically ...
Breaking Medicine Technology:First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 2First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 3First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection 4Spring Bank Pharmaceuticals Initiates a Phase I Clinical Trial for SB 9200 in HCV-infected Patients 2Spring Bank Pharmaceuticals Initiates a Phase I Clinical Trial for SB 9200 in HCV-infected Patients 3Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 2Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 3
... , , , , , , ... MIVI-TRUST Phase III Program With Microplasmin Recruits a Total of Over,640 ... (Euronext Brussels: THR), a biopharmaceutical company,focused on the discovery and development ... that it has completed,the enrolment of the second Phase III trial ...
... , NORCROSS, Ga., Dec. 15 Immucor, Inc. (Nasdaq: ... to the blood transfusion industry, today announced that it will ... 6, 2010 after the market close. The Company will host ... a.m. (Eastern Time) to discuss the results. , ...
Cached Medicine Technology:ThromboGenics Completes Patient Enrolment of Second Phase III Trial of Microplasmin for the Non-Surgical Treatment of Eye Disease 2ThromboGenics Completes Patient Enrolment of Second Phase III Trial of Microplasmin for the Non-Surgical Treatment of Eye Disease 3ThromboGenics Completes Patient Enrolment of Second Phase III Trial of Microplasmin for the Non-Surgical Treatment of Eye Disease 4
...
...
The AGC Revision Knee, extends the AGC Family to include implants for severe primary knees or revision. Provides rotational freedom of +/- 2 and varus/valgus freedom of +/- 1.5....
The Performance Knee System is a wide and easy to use system that offers enough options to cover any indication for primary and revision knee surgery, and all this with extensive intraoperative flexi...
Medicine Products: