Navigation Links
Important Data Presented on Independent Predictors of Mortality in Patients With Idiopathic Pulmonary Fibrosis
Date:5/17/2009

consistent with previous studies, the most frequently reported side effects were gastrointestinal symptoms and rash.

An exploratory analysis of pooled data from both trials revealed that treatment with pirfenidone resulted in a 30% relative reduction in the percentage of patients who experienced an absolute decline in percent predicted FVC of at least 10%. This magnitude of decline is considered clinically meaningful as a decline in percent predicted FVC as small as 5% over a six-month period has been shown to be an independent predictor of mortality in patients with IPF, as reported in the du Bois presentation at ATS.

InterMune expects to submit a new drug application (NDA) to the FDA in the summer of 2009 and a marketing authorization application (MAA) to the European authorities around the end of 2009.

About IPF

Idiopathic pulmonary fibrosis (IPF) is a disabling and ultimately fatal disease that affects a total of approximately 200,000 people in the United States and Europe, with approximately 30,000 new cases developing in the United States alone, each year. There are no medicines approved by the U.S. Food and Drug Administration (FDA) or European Medicines Evaluation Agency (EMEA) for the treatment of IPF. On October 16, 2008, pirfenidone was approved for marketing in Japan as Pirespa(R), the first regulatory approval of any treatment for IPF in any major market in the world. IPF is characterized by inflammation and scarring (fibrosis) in the lungs, hindering the ability to process oxygen and causing shortness of breath (dyspnea) and cough. IPF is a progressive disease, meaning that over time, lung scarring and symptoms increase in severity. The median survival time from diagnosis is two to five years.

About Pirfenidone

Prior in-vitro evidence has shown that pirfenidone inhibits collagen synthesis, down-regulates profibrotic cytokines and decreas
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. CMSA Delivers Important Message to Congress: Case Management Services Improve Patient Care and Should Be Key Strategy in Health Care Reform Initiatives
2. What Motivates Physicians to Succeed? Money Isn't Most Important
3. Major statin study reveals several important findings for reducing prostate cancer and disease
4. Leapfrog Group Hospital Survey Finds Majority of Hospitals Fail to Meet Important Quality Standards
5. New Research Shows Tree Nuts May Play an Important Role in the Health of People With Diabetes
6. UT Southwestern researchers reveal how the brain processes important information
7. Nu Skin Charitable Promotion Reaches Important Milestone: 100,000 Trees Donated to African Nation of Malawi
8. AUDIO from Medialink and Mens Health Network: Important Decision Regarding Prostate Cancer
9. Penn researchers identify new protein important in breast cancer genes role in DNA repair
10. Important new model shows how proteins find the right DNA sequences
11. Why Blood and Bone Marrow Donors Are So Important: Extreme Makeover: Home Edition Profiles Blood Drive Honoree Lizzie Bell
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... "My niece developed a nighttime fever, and I ... fever might get worse," said an inventor from Montgomery, ... how she was doing, I developed this monitoring system." ... a child's temperature. The unit instantly alerts parents if ... medical care can be given, which is designed to ...
(Date:8/30/2014)... 2014 The federal judge overseeing ... http://www.injurybeacon.com/transvaginal-mesh/ ) filed against Boston Scientific Corp. has ... selected for one of the proceeding’s bellwether trials. ... 2014, U.S. District Judge Joseph R. Goodwin of ... Boston Scientific’s contention that a consolidated trial would ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 In today’s world, ... difficult to get. Snoring and sleep apnea (a medical problem ... people and their bed partners of the rest they need ... of the population snores and 20 million people in the ... have been diagnosed and treated; and of those treated, many ...
(Date:8/30/2014)... 2014 Top10BestSEOHosting.com is a well-known ... announced that HostGator.com http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts is the ... Also, they has announced that Bluehost and Arvixe ... Hostgator, one of the Top 10 Web Hosting ... Windows hosting, and it offers rich features and ...
(Date:8/30/2014)... August 30, 2014 August 28th, 2014: ... pain in our society and the toll that takes ... it’s vital that continuing education for physical therapists addresses ... help physical therapists help others, Hands-On Seminars is offering ... , Three learning styles are available to fit ...
Breaking Medicine News(10 mins):Health News:Transvaginal Mesh Lawsuit News: Federal Judge Refuses Boston Scientific Request for Separate Trials in Four Bellwether Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuit News: Federal Judge Refuses Boston Scientific Request for Separate Trials in Four Bellwether Cases, Bernstein Liebhard LLP Reports 3Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Top10BestSEOHosting.com: HostGator.com Is The Best Windows Hosting Supplier 2Health News:Leader in Manual Therapy Continuing Education Makes it Easier for Physical Therapists to Improve Results on Patients 2
... causes bloodstream infections is five times more lethal than other ... potent antibiotic drug vancomycin used to treat MRSA, according to ... 50 percent of the patients infected with the strain died ... with other MRSA strains. The average 30-day mortality ...
... During Last Year,s ,One Million Tests, World AIDS Day ... Testing Goal by Testing 35,034 , PHNOM PENH, Cambodia, ... to test several million people for HIV in observance of ... 2009 campaign, AHF/Cambodia CARES will launch its inaugural testing effort ...
... most seriously ill, experts say , SATURDAY, Oct. 31 (HealthDay ... to double the risk of stroke in patients with diabetes ... a new study finds. , Darbepoetin alfa, marketed as ... prescribed for diabetic patients with chronic kidney disease and mild ...
... Amgen (Nasdaq: AMGN ) today announced the ... Cardiovascular Events with Aranesp® Therapy), a large, randomized, double-blind, ... kidney disease (CKD) not on dialysis, moderate anemia and ... New England Journal of Medicine and presented ...
... Long Beach, CA; December 8, 2009 , NEEDHAM, ... announced that a special event, Terminology Services Information Day, will ... CA USA on December 8, 2009. For more information and ... http://www.omg.org/terminology-services-day . , (Logo: http://www.newscom.com/cgi-bin/prnh/20090629/DC39325LOGO ...
... based in McAllen, Texas, has agreed to pay the United ... False Claims Act, the Anti-Kickback Statute and the Stark Statute ... in order to induce them to refer patients to hospitals ... L.P., d/b/a/ South Texas Health System, is a subsidiary of ...
Cached Medicine News:Health News:Henry Ford Hospital study: A MRSA strain linked to high death rates 2Health News:Cambodia: World AIDS Day HIV Campaign, 'Testing Millions,' to Again Launch During Cambodia's National Water Festival 2Health News:Anemia Drug May Raise Stroke Risk in Kidney Patients 2Health News:Anemia Drug May Raise Stroke Risk in Kidney Patients 3Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 2Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 3Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 4Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 5Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 6Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 7Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 8Health News:Large Study of Anemia Treatment in Chronic Kidney Disease Patients Not on Dialysis Published in the New England Journal of Medicine Failed to Meet Primary Efficacy Endpoints 9Health News:OMG Announces Special Event: Terminology Services Information Day 2Health News:OMG Announces Special Event: Terminology Services Information Day 3Health News:Texas Hospital Group Pays U.S. $27.5 Million to Settle False Claims Act Allegations 2Health News:Texas Hospital Group Pays U.S. $27.5 Million to Settle False Claims Act Allegations 3
(Date:8/30/2014)... , Aug. 30, 2014   Royal Philips  ... Affiniti, a new ultrasound system designed to ... demands of increasing patient volumes and cost pressures. Making ... 2014 in Barcelona this ... facing more patients with fewer resources deliver high quality ...
(Date:8/29/2014)... , Aug. 29, 2014 /PRNewswire-iReach/ -- Market Research ... Industry, 2009-2019 is a professional and in-depth market ... Scanner industry . The report firstly reviews the ... classification, application and manufacturing technology. The report then ... Crystallography Scanner listing their product specification, capacity, Production ...
(Date:8/29/2014)... 2014  Chuma Holdings, Inc. (OTCBB:CHUM) (the "Company"), ... support services for the lawfully organized cannabis industry, ... approved the Company,s name and symbol change request. ... be known as Chuma Holdings, Inc. ... merger with the Company,s wholly-owned subsidiary, Chuma Holdings, ...
Breaking Medicine Technology:Philips Debuts New Affiniti Ultrasound System at the European Society of Cardiology Congress 2014 2Philips Debuts New Affiniti Ultrasound System at the European Society of Cardiology Congress 2014 3Philips Debuts New Affiniti Ultrasound System at the European Society of Cardiology Congress 2014 4X-Ray Crystallography Scanner Industry For Global and Chinese Market Forecast to 2019 2X-Ray Crystallography Scanner Industry For Global and Chinese Market Forecast to 2019 3X-Ray Crystallography Scanner Industry For Global and Chinese Market Forecast to 2019 4X-Ray Crystallography Scanner Industry For Global and Chinese Market Forecast to 2019 5CannaMed Announces Name Change and Trading Symbol Change 2CannaMed Announces Name Change and Trading Symbol Change 3
... 28 The U.S. Food and Drug Administration ... for the treatment of a rare blood cancer ... Philadelphia chromosome positive chronic phase chronic myeloid leukemia ... bone marrow disease linked to a genetic abnormality. ...
... Aethlon Medical, Inc. (OTC Bulletin Board: ... to address infectious disease and cancer, announced today that ... Aethlon Medical.  Aethlon Chairman and CEO, Jim Joyce, previously ... joined Aethlon,s Board of Directors and will retain his ...
Cached Medicine Technology:FDA Approves Additional Medical Indication for Sprycel 2FDA Approves Additional Medical Indication for Sprycel 3Aethlon Medical Names Rod Kenley President 2Aethlon Medical Names Rod Kenley President 3Aethlon Medical Names Rod Kenley President 4Aethlon Medical Names Rod Kenley President 5
Multiple Modulation Phaco (MMP) programmability with eight surgeon settings for maximum versatility. The combination of the peristaltic power balanced pump and the piezoelectric handpiece results in ...
... The Precisionist workstation is a ... operating system allowing infinite flexibility for ... to meet the demands of changing ... A new concept in ophthalmic surgical ...
A gentle yet highly effective corneal rust ring remover with Alger brush of 1mm burr. Runs off 1 x AA battery, no switches, simply spin mandrel to operate....
Foreign body removal system. Designed to aid in the removal of foreign bodies and corneal rust rings....
Medicine Products: