Navigation Links
Importance of preventing congestion in heart failure
Date:6/4/2009

Philadelphia, PA, 4 June 2009 Preventing vascular congestion is an important mediator in heart failure, reports a study in the June issue of the Journal of Cardiac Failure (http://www.onlinejcf.com/), published by Elsevier.

The authors previously demonstrated that venous endothelium is a key regulator of central blood volume, organ perfusion and hemostasis in heart failure (HF). The present study demonstrates that in venous endothelium, inflammatory/oxidative and hemostatic programs were significantly activated in HF dogs compared to normal dogs. In normal dogs, fluid loading significantly activated these same programs to levels that approached those seen in dogs with HF.

These findings suggest that biomechanical stress (i.e. vascular stretch) may be an important mediator of these endothelial responses, and highlight the importance of preventing congestion. Further investigation is needed to clarify whether the venous endothelial phenotype in unique individuals may ultimately allow us to track the vascular impact of subsequent environmental (i.e. biomechanical and biochemical) stressors, as well as the potential response to therapeutic interventions.

"This important study is consistent with a growing literature, indicating that congestion itself may mediate many of the physiological abnormalities in heart failure, such as vascular dysfunction, inflammation, renal dysfunction and hypercoagulability," commented Barry M. Massie, M.D., Editor-in-Chief of the Journal of Cardiac Failure.


'/>"/>

Contact: Maureen Hunter
m.hunter@elsevier.com
215-239-3671
Elsevier
Source:Eurekalert

Page: 1

Related medicine news :

1. Recent smoking-cessation research highlights importance of keeping teens from smoking
2. NBA All-Star Amare Stoudemire Discusses Season-Ending Eye Injury and the Importance of Protective Eyewear
3. Filling the gap: The importance of Medicaid continuity for former inmates
4. Step to the Plate - Register to Donate Aims to Educate Baseball Fans About the Importance of Organ Donation and Increase Registrations
5. Concord Coalition Says New Trustees Report Demonstrates the Importance of Health Care Cost Control
6. Mom Offers Personal Mother's Day Message on Importance of Annual Mammograms
7. Latino Coalition Highlights Importance of Personal Health Records At Economic Summit
8. Swine Flu Reinforces the Importance of Preparing for Emergencies, Says APHA
9. Survey research shows many Americans are aware of importance of voice care
10. Martek, March of Dimes Partner to Promote Importance of DHA
11. PA Education Secretary Emphasizes Importance of Breakfast for Student Performance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... a one-day corporate governance program for mid-market executives as a kick-off to the ... held Sunday, Sept. 24, 2017 on the University of Pennsylvania campus, followed by ...
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... insurance management and financial planning assistance to clients in southern Montana, is announcing ... offered by Zoo Montana. , The outreach programs offered by Zoo Montana provide ...
(Date:6/27/2017)... ... June 27, 2017 , ... Excel Medical, ... Finnegan to the position of Executive Vice President, Sales and Marketing. Finnegan is ... telehealth and medical device sales leadership. He has received industry recognition for innovations ...
(Date:6/27/2017)... , ... June 27, 2017 , ... ... solution for many of the health care industry’s hospitals and provider groups, has ... financing portal for select customers. Parasail Health is a San Francisco health-finance startup ...
(Date:6/27/2017)... ... 27, 2017 , ... A January 18th article on medGadget reports ... billion by the year 2024 according to a new report. The article also notes ... from titanium. Los Angeles area clinic Beverly Hills Periodontics & Dental Implant Center says ...
Breaking Medicine News(10 mins):
(Date:6/9/2017)... INDIANAPOLIS , June 9, 2017 /PRNewswire/ ... diabetes. In a further effort to help spread lessons ... this condition, the International Diabetes Federation (IDF) and Eli ... come together for the second phase of the Bringing ... (BRIDGES 2), reaffirming their commitment to helping people with ...
(Date:6/8/2017)... Texas , June 8, 2017 /PRNewswire/ ... a leading developer and manufacturer of diagnostic ... announced today that Cressey & Company LP ... firm, has completed a growth-focused investment in ... a majority ownership position from selling shareholder, ...
(Date:6/7/2017)... , June 6, 2017  Diplomat Specialty Infusion Group, a brand ... environment to its Iowa location. ... now features an ISO 7 cleanroom—the standard needed to ... with a low level of pollutants. ... nutrition consumers and better serve our Iowa ...
Breaking Medicine Technology: