Navigation Links
Implanted Heart Devices Have Real-World Benefits: Study
Date:1/4/2013

FRIDAY, Jan. 4 (HealthDay News) -- Implantable heart defibrillators aimed at preventing sudden cardiac death are as effective at ensuring patient survival during real-world use as they have proven to be in studies, researchers report.

The new finding goes some way toward addressing concerns that the carefully monitored care offered to patients participating in well-run defibrillator investigations may have oversold their related benefits by failing to account for how they might perform in the real-world.

The study is published in the Jan. 2 issue of the Journal of the American Medical Association.

"Many people question how the results of clinical trials apply to patients in routine practice," lead author Dr. Sana Al-Khatib, an electrophysiologist and member of the Duke Clinical Research Institute in Durham, N.C., acknowledged in a journal news release. "[But] we showed that patients in real-world practice who receive a defibrillator, but who are most likely not monitored at the same level provided in clinical trials, have similar survival outcomes compared to patients who received a defibrillator in the clinical trials."

The findings stem from a survival analysis (involving data collected since 2005 by a large national Medicare registry) following implantation with the small electrical devices known as implantable cardioverter-defibrillators (ICDs) that are connected by wire to the heart and designed to provide a life-saving electronic pulse if and when the heart stops beating.

The research team compared the performance of such devices among more than 5,300 real-world patients with the performance observed among more than 1,500 patients who had participated in clinical defibrillator studies. The authors stressed that the demographics of the two groups were comparable, with no particularly sick or elderly individuals included in the real-world pool.

But while the analysis revealed comparable results among both groups, the authors stressed that their findings clearly could not speak to how older and sicker patients might fare outside the confines of a study situation, which itself often favors the inclusion of younger/healthier patients.

"That is an issue, and the only way to get at that is to randomly assign such patients to either receive an ICD or not in a clinical trial," Al-Khatib said in the news release. "Even without those data, however, our study gives patients and their health care providers reassurance that what we have been doing in clinical practice has been helpful, and is improving patient outcomes. Our findings support the continued use of this life-saving therapy in clinical practice," she added.

More information

For more on ICDs, visit the U.S. National Heart, Lung, and Blood Institute.

-- Alan Mozes

SOURCE: Journal of the American Medical Association, news release, Jan. 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny implanted coil improves lung function in patients with severe emphysema
2. Device implanted in brain has therapeutic potential for Huntingtons disease
3. Study shows how to reduce inappropriate shocks from implanted defibrillators
4. Women Dont Fare as Well as Men With Implanted Defibrillators: Study
5. Witnessing, Experiencing Traumatic Events May Worsen Heart Disease
6. Risk of suicide and fatal heart attack immediately following a cancer diagnosis
7. Cancer Diagnosis May Raise Odds for Suicide, Heart Attack Death
8. In children born with severe heart defect, surgical management has little effect on neuro outcomes
9. Invasive heart test being dramatically overused, Stanford study shows
10. Heart failure patients with diabetes may benefit from higher glucose levels
11. Omega-3 Supplements No Help Against Repeat Heart Trouble: Review
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Implanted Heart Devices Have Real-World Benefits: Study
(Date:1/21/2017)... ... ... Seamild, the largest manufacturer of oats in China, is now aiming at global ... is recognized globally as one of the healthiest cereals, XieQingkui, the founder of Seamild, ... move to sow the seed of good karma. Buddhism spirit featuring benevolence and sacrifice ...
(Date:1/21/2017)... Pekin, IL (PRWEB) , ... January 21, 2017 , ... ... disorders. Even when individuals experience the freedom of recovery, they often feel shame for ... abuse and post-traumatic stress disorder (PTSD). In the workshop, “Rising Strong in Life After ...
(Date:1/20/2017)... ... January 20, 2017 , ... Source Vitál Apothecary, a skin and ... essential oils, announced the company had a successful visit to the 2017 ECRM Diet, ... gives companies that work in the nutritional, sports and health industries a chance to ...
(Date:1/20/2017)... ... January 20, 2017 , ... International Protein, a company based out ... announced it attended the January ECRM trade show in Hilton Head, SC. , ... was determined to create a line of products that would elevate her fitness regime. ...
(Date:1/20/2017)... ... ... “The Angel”: a heartwarming and earnest tale of faith and believing in the ... is the creation of published author, Marjorie Lund-Fontaine, a former professional violinist, alumnus of ... asked of her new book, Marjorie says, “‘The Angel’ was written as a fairytale, ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Conference Call and Webcast to ... ) today announced it will release results for the fourth quarter ... ... host a conference call at 4:30 PM ET on Wednesday, February ... full year 2016 financial results and other corporate activities. To participate ...
(Date:1/19/2017)... , Jan. 19, 2017 This report ... current and future scenario of the global market. Large ... opioid consumption. Severe chronic constipation is a major side ... traditional laxatives. Hence, novel targeted therapy has been prescribed ... sufferers, launch of targeted medicines, and growing awareness about ...
(Date:1/19/2017)...  Stealth BioTherapeutics Inc. ( Stealth ), a clinical-stage ... announced new additions to its senior leadership team: ... and Daniel Geffken as interim Chief Financial ... , Pharm.D. has been promoted to Chief Clinical Development ... Doug and Daniel to our management team, as both ...
Breaking Medicine Technology: