Navigation Links
Implanted Heart Devices Have Real-World Benefits: Study
Date:1/4/2013

FRIDAY, Jan. 4 (HealthDay News) -- Implantable heart defibrillators aimed at preventing sudden cardiac death are as effective at ensuring patient survival during real-world use as they have proven to be in studies, researchers report.

The new finding goes some way toward addressing concerns that the carefully monitored care offered to patients participating in well-run defibrillator investigations may have oversold their related benefits by failing to account for how they might perform in the real-world.

The study is published in the Jan. 2 issue of the Journal of the American Medical Association.

"Many people question how the results of clinical trials apply to patients in routine practice," lead author Dr. Sana Al-Khatib, an electrophysiologist and member of the Duke Clinical Research Institute in Durham, N.C., acknowledged in a journal news release. "[But] we showed that patients in real-world practice who receive a defibrillator, but who are most likely not monitored at the same level provided in clinical trials, have similar survival outcomes compared to patients who received a defibrillator in the clinical trials."

The findings stem from a survival analysis (involving data collected since 2005 by a large national Medicare registry) following implantation with the small electrical devices known as implantable cardioverter-defibrillators (ICDs) that are connected by wire to the heart and designed to provide a life-saving electronic pulse if and when the heart stops beating.

The research team compared the performance of such devices among more than 5,300 real-world patients with the performance observed among more than 1,500 patients who had participated in clinical defibrillator studies. The authors stressed that the demographics of the two groups were comparable, with no particularly sick or elderly individuals included in the real-world pool.

But while the analysis revealed comparable results among both groups, the authors stressed that their findings clearly could not speak to how older and sicker patients might fare outside the confines of a study situation, which itself often favors the inclusion of younger/healthier patients.

"That is an issue, and the only way to get at that is to randomly assign such patients to either receive an ICD or not in a clinical trial," Al-Khatib said in the news release. "Even without those data, however, our study gives patients and their health care providers reassurance that what we have been doing in clinical practice has been helpful, and is improving patient outcomes. Our findings support the continued use of this life-saving therapy in clinical practice," she added.

More information

For more on ICDs, visit the U.S. National Heart, Lung, and Blood Institute.

-- Alan Mozes

SOURCE: Journal of the American Medical Association, news release, Jan. 1, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny implanted coil improves lung function in patients with severe emphysema
2. Device implanted in brain has therapeutic potential for Huntingtons disease
3. Study shows how to reduce inappropriate shocks from implanted defibrillators
4. Women Dont Fare as Well as Men With Implanted Defibrillators: Study
5. Witnessing, Experiencing Traumatic Events May Worsen Heart Disease
6. Risk of suicide and fatal heart attack immediately following a cancer diagnosis
7. Cancer Diagnosis May Raise Odds for Suicide, Heart Attack Death
8. In children born with severe heart defect, surgical management has little effect on neuro outcomes
9. Invasive heart test being dramatically overused, Stanford study shows
10. Heart failure patients with diabetes may benefit from higher glucose levels
11. Omega-3 Supplements No Help Against Repeat Heart Trouble: Review
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Implanted Heart Devices Have Real-World Benefits: Study
(Date:2/10/2016)... ... 2016 , ... LaserShip, a regional parcel carrier that services the eastern U.S., ... last Friday in order to aid in the Flint water crisis. In 2014, LaserShip ... located in Clio, only 15 miles away from Flint. , “We have deep roots ...
(Date:2/10/2016)... ... February 10, 2016 , ... Western University of Health ... to the developmentally disabled in the Coachella Valley. , The two entities, through ... at 71-949 Highway 111, Suite 100-B, in Rancho Mirage, California. The new site ...
(Date:2/10/2016)... ... ... As part of its ongoing series of aquatic therapy related webinars, HydroWorx is ... expert and thoughtful presentation to give attendees a better sense of how to use ... to attend, but registration is required. , Rehabilitation of Offensive Lineman Utilizing ...
(Date:2/10/2016)... ... February 10, 2016 , ... Intermedix announced on ... Medicine , an emergency medicine professional association, to support the organization's newly established ... American Academy of Emergency Medicine, or AAEM, seeks to empower emergency physicians to ...
(Date:2/10/2016)... TX (PRWEB) , ... February 10, 2016 , ... ... commencement of a master charity program created to assist the local community. Pledging ... with community leaders and nonprofit organizations in the area. Their goal is to ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Biotechnology Inc., spurred by a major "team investment" by Bruce Montgomery , one of this ... A-Round, according to CEO Leen Kawas , PhD. ... ... ... Kawas said the round was intended ...
(Date:2/11/2016)... CARLSBAD, Calif. , Feb.11, 2016  Ionis Pharmaceuticals, Inc. ... a live webcast on Thursday, February 25 at 11:30 a.m. ... on pipeline and business progress. www.ionispharma.com . ... at the same address. --> www.ionispharma.com . A ... the same address. --> Interested parties may listen ...
(Date:2/11/2016)... -- Indiso ltd , a medical technology company ... respiratory diseases announced today positive results in its clinical ... patients show improvements in respiratory functions and other clinical ... Upper and lower respiratory tract diseases and allergy ... reached epidemic level. Increasing number of studies however show ...
Breaking Medicine Technology: