Navigation Links
Implantable Cancer Vaccine Shows Promise

In mice, disks placed under the skin kill tumor cells, study finds

WEDNESDAY, Nov. 25 (HealthDay News) -- A cancer vaccine delivered in a fingernail-size implant eliminated melanoma tumors in mice, a new study reports.

The method uses polymer disks, 8.5 millimeters in diameter, that are loaded with tumor-specific antigens and implanted under the skin to reprogram the immune system to attack tumors. The Harvard University scientists who developed the implant predicted that it would be more effective and easier to use than other cancer vaccines currently in clinical trials.

"Inserted anywhere under the skin -- much like the implantable contraceptives that can be placed in a woman's arm -- the implants activate an immune response that destroys tumor cells," David J. Mooney, a bioengineering professor, said in a Harvard news release.

The disks release cytokines, which are powerful recruiters of immune-system messengers called dendritic cells. The cells are able to enter the implant, where they're exposed to antigens specific to the type of tumor being targeted in a particular individual. The dendritic cells then "report" to nearby lymph nodes, where they tell immune system T cells to seek and destroy tumor cells.

Because the method targets only tumor cells, there is no damage to healthy tissue, like there is with chemotherapy, the researchers noted.

The successful test results with mice are reported in the Nov. 25 issue of Science Translational Medicine.

More information

The U.S. National Cancer Institute has more about cancer vaccines.

-- Robert Preidt

SOURCE: Harvard University, news release, Nov. 25, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Implantable device designed to detect, stop seizures under study at MCG
2. GrantAdler Shipping Novel Implantable Vascular Access Port
3. URGENT Thoratec Corporation Worldwide Recall of Implantable Ventricular Assist Device
4. EaglePicher Technologies Introduces First Implantable Medical Cell Designed Specifically for Monitoring Applications
5. Implantable medical devices may expose patients to security, privacy risks; solutions suggested
6. Northwestern Memorial trials implantable device to manage congestive heart failure symptoms
7. Texcel Introduces Innovative Programmable, Implantable Stimulation System for R&D of Specialty Stimulation Therapies
8. Long-Term Results of VisionCares Implantable Telescope for End-Stage Macular Degeneration Published in the American Journal of Ophthalmology
9. MP3 headphones interfere with implantable defibrillators, pacemakers
10. Implantable monitor may help in managing diastolic heart failure
11. Access MediQuip and WellPoint Finalize First National Contract for Implantable Medical Devices
Post Your Comments:
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from reveals ...
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... LAS VEGAS , June 26, 2016 ... movement to value-based care operating models within the health ... that enable greater financial efficiency , Deloitte offers ... address the key business issues impacting efficient cost optimization: ... alignment , These services facilitate better outcomes and ...
(Date:6/24/2016)... Dublin - ... " Global Markets for Spectroscopy Equipment" report ... This report focuses on the global market of ... applications in various applications. The report deals with spectroscopy ... industries: pharmaceutical and biotechnology, food and beverage, and environmental ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: