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Impaired quality of life: A warning signal after oesophageal cancer surgery
Date:1/4/2012

A new study published in the Journal of Clinical Oncology shows that most patients who survive for at least five years after oesophageal cancer surgery recover an average quality of life. However, quality of life deteriorates significantly for one in six patients to a level that remains much lower than the average population in the five years after surgery. This suggests, say the researchers, that hospitals must be better at identifying this patient group.

Globally, oesophageal cancer is the eighth most common form of cancer. The prognosis is a poor one, and only 10 per cent of patients survive five years after diagnosis. The disease is often discovered in a late stage after symptoms such as swallowing difficulties and weight loss appear. The only established curative treatment includes extensive surgery, often of the abdomen, chest and throat. Some 30 per cent of patients survive the operation at least five years. The purpose of the current study was to establish if the quality of life among five-year survivors of surgery for oesophageal cancer is on a par with that of the average population.

The study included 117 patients who had undergone surgery for oesophageal cancer in Sweden between 2001 and 2005, and survived at least five years. The patients were asked to answer a quality of life questionnaire that measured a range of functions (e.g. physical, social and emotional) and symptoms (e.g. pain, fatigue and eating difficulties). To obtain an idea of what their quality of life was like before the operation, the researchers had a group of 4,910 randomly selected individuals answer the same questions. The replies were then re-calculated as points on a 0-100 scale, where high scores for functions and low ones for symptoms were good. The analyses were adjusted for age, sex and medical state of health.

What they found was that most patients had an unchanged or even improved quality of life, and one that was comparable with that
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