Navigation Links
Impaired kidney function raises risk of heart problems in the elderly
Date:1/20/2009

A study published next week in the open access journal PLoS Medicine suggests that elderly people with damaged kidneys are at greater risk of cardiovascular disease, such as heart failure and stroke, and other causes of mortality. The findings indicate that greater efforts should be made to encourage elderly people who have impaired kidney function alongside other risk factorssuch as high blood cholesterol and high blood pressure, which are often a result of smoking and dietto make lifestyle changes to avoid developing cardiovascular problems.

Most countries face increasing rates of cardiovascular disease and it is the single leading cause of death in the United States and many European countries. It has already been established that young and middle-aged people with a reduced estimated glomerular filtration rate (eGFR)the measurement of the movement of waste and excess fluid through the kidneysare more likely to develop cardiovascular disease than those with healthy kidneys. To establish how at risk elderly people with impaired kidney function were, Ian Ford of the University of Glasgow and colleagues analysed existing data from a three year clinical trial conducted among men and women aged between 70 and 82 in Scotland, Ireland and the Netherlands.

The trialknown as the Prospective Study of Pravastatin in the Elderly at Risk, or PROSPER trialhad been designed to test the effect of the statin pravastatin on the development of cardiovascular disease. Dividing the trial participants into four groups based on their eGFR at the start of the study, Ian Ford and colleagues established that the patients with a low eGFRthose with the most impaired kidney functionwere twice as likely to die from any cause as those with healthier kidneys. They also established that the patients with the most damaged kidneys were three times more likely to have non-fatal heart failure or disease and were more likely to die as a result of heart disease or failure.

The data also showed that treatment with the drug pravastatin reduced the number of fatal and non-fatal heart problems more effectively amongst the group of patients with the most damaged kidneysalthough the researchers warn that this finding is statistically borderline and say the most that can be concluded is that there is no reason to exclude elderly people with damaged kidneys from treatment with statins, the drugs that reduce blood cholesterol levels in those at risk of cardiovascular disease.


'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Related medicine news :

1. Prognosis after attempted suicide impaired by psychiatric disorder
2. Quick Medical and Clarity Partner to Help Meet the Needs of the Hearing Impaired
3. Virginia Rehabilitation Center for the Blind and Vision Impaired Celebrates Opening of New Student Dormitory
4. Hybrid Cars Pose Risk to Blind, Visually Impaired
5. Major rise in Caesarean sections linked to impaired womb function with age
6. Human Stem Cell Transplant Helps Brain-Impaired Mice
7. Genetic links to impaired social behavior in autism
8. Commonly used medications associated with impaired physical function in older adults
9. New Web Community Brings Together Parents of Visually Impaired Children
10. Traffic exhaust can cause asthma, allergies and impaired respiratory function in children
11. Impaired sense of smell may be early indicator of Parkinsons disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to ... unique items from across the nation, this holiday-themed event will raise funds and awareness ... VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented ... the lowdown on sciatica in a new episode of "Success Files," which is ... events and innovation and investigates each subject in-depth with passion and integrity. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... First ... compliance program management, will showcase a range of technology and learning solutions at ... (NCAL) Convention and Expo to be held October 14–18, 2017 at the Mandalay ...
(Date:10/12/2017)... ... 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one of ... innovative new design of the shoulder pad. The shoulder pad provides optimal support ... your pain while using cold therapy. By utilizing ice and water that is circulated ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided ... Piedras, Puerto Rico , where the ... Following a comprehensive onsite ... structural damage, temporary loss of power and minimal water ... manufacturing operations have resumed, and the company expects to ...
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
(Date:10/2/2017)... 2, 2017  AllianceRx Walgreens Prime, the combined central ... and pharmacy benefit manager Prime Therapeutics LLC (Prime), today ... included the unveiling of new signage at its headquarters ... as at a few other company-owned facilities across the ... patients, some of whom will begin to see the ...
Breaking Medicine Technology: