Navigation Links
Immunotherapy Demonstrates Long-Term Success in Treating Lymphoma
Date:11/1/2009

est their theory, the team infused EBV-specific CTL lines into two groups of patients: those who were undergoing HSCT and were at high risk of developing EBV-lymphoma, and patients who had already developed lymphoma. The study reported that CTL treatment successfully prevented the development of EBV-lymphoma in all 101 patients in the at-risk group who received the therapy prophylactically and achieved sustained complete remission in 11 of the 13 patients (85 percent) treated therapeutically (those who already had the disease).

"Therapy with EBV-specific CTLs was effective for these severely immunocompromised patients. The CTLs successfully reached tumors, multiplied, and were able to kill the tumor cells," said lead study author Helen Heslop, MD, of the Center for Cell and Gene Therapy at Baylor College of Medicine, The Methodist Hospital, and Texas Children's Hospital.

While the successful outcomes result from a number of factors in the study, the researchers attribute some of the success of the trial to the time of treatment. The CTL lines were infused soon after stem cell transplantation, when the existing white blood cell count was still low and was not quickly regenerating, allowing the infused cells to more quickly multiply and mediate anti-viral and anti-tumor effects. In addition, by marking and tracking the CTL genes, the team was able to demonstrate that the cells could survive for up to nine years in the body, conferring long-term protection.

With strong clinical outcomes, the study team is working to determine the most appropriate role and timing for CTL infusions. Some newer therapies (such as monoclonal antibodies) offer prophylactic and therapeutic options but cannot offer long-term protection. Therefore, treatment with CTLs may be reserved for the highest risk patients - those with a diagnosis of immune deficiency or a history of EBV-lymphoma, or those who develop elevated EBV levels after therapy with monoclonal
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Johnson & Johnson and Elan Corporation plc Announce Closing of Transaction Related to Alzheimers Immunotherapy Program and Equity Investment
2. Johnson & Johnson and Elan Corporation plc Announce Definitive Agreement for Alzheimers Immunotherapy Program and Equity Investment
3. Immunotherapy effective against neuroblastoma in children
4. Sublingual immunotherapy for inhalant allergies deserves deeper consideration
5. Prostate cancer immunotherapy significantly prolongs survival in men with advanced prostate cancer
6. Device aims to decrease wait period for patients needing immunotherapy
7. A new light on tumor immunotherapy for gastric cancer
8. Three Italian Multicenter Studies Report High (>70%) Rates of Complete Remission (CR) Utilizing Zevalin Radio-Immunotherapy (RIT) in Treatment of Newly Diagnosed or Relapsed or Refractory Non-Hodgkins Lymphoma
9. 33rd Annual Hutch Holiday Gala Raises Millions for Cancer Immunotherapy Research
10. MaxCyte to Present Targeted Cancer Immunotherapy Product at 50th Annual Meeting of the American Society of Hematology
11. Towards improved immunotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... 2015 , ... Super Bowl 50 will emanate from Levi’s Stadium in Santa Clara, ... is the Super Bowl. In the two weeks that separate the conference championships and the ... 2016 Super Bowl game will mark the 50th time it has been held and the ...
(Date:7/31/2015)... ... 31, 2015 , ... Precision Aesthetics is New York’s only Thermage skin tightening ... first provider of Exilis non-surgical fat reduction in New York. Due to its ... large International clientele. Many patients travel to New York to get their non-surgical ...
(Date:7/31/2015)... ... July 31, 2015 , ... Last week, the Mesothelioma Applied ... can be accessed by visiting http://www.curemeso.org/store . , “Our new store features ... part: whenever a product is purchased, the Meso Foundation receives a $5.00 donation,” ...
(Date:7/31/2015)... ... July 31, 2015 , ... Sculpted Contours Luxury Medical ... PRO this week. Zeltiq Aesthetics released this new applicator in the United States ... for treating the outer thighs. The original applicator required a 2 hour treatment ...
(Date:7/31/2015)... ... 2015 , ... Jacksonville-based drug and alcohol rehabilitation center, Lakeview ... The medical community, social workers, law enforcement, and government officials are all invited ... effort to better understand and combat sex trafficking. Lead by sex trafficking expert ...
Breaking Medicine News(10 mins):Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3Health News:Cooler Coolsculpting in Atlanta: Treatments Now Twice As Fast 2Health News:Cooler Coolsculpting in Atlanta: Treatments Now Twice As Fast 3Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3
... syndrome) has been a major killer in the last two ... worldwide and infected a further 8,000. A collaborative group of ... past year screening more than 8,000 existing drugs to find ... 15 existing drugs that have the potential to kill the ...
... the womb of the mother, may have asthma at a ... an 11-year observation of incidence of asthma and other respiratory ... to incidence of asthma in childhood. Passive smoking by the ... of asthma in children. ,Researchers are of the opinion ...
... Parkinson's disease is a neurodegenerative disease of the substantia nigra ... first discovered and its symptoms documented in 1817 by the ... in the brain of patients were identified in the 1960s. ... a mystery. , ,In a study done recently it ...
... have found sections of the // chromosomes of lung ... ,In a study in the July 1 issue ... nucleotide polymorphism (SNP) array technology, which focuses on the ... chromosomes where genes were either left out or multiplied ...
... autistic children have led to a fear in the world ... epidemic. However a recent report, which was published in the ... is not true. The report points out to certain facts ... ,The study had pointed out that recent changes in the ...
... that walking on a cobblestone mat surface resulted in ... physical performance among the age groups of 60 and ... said that Compared to conventional walking, the experience ... manufactured cobblestone mats improved participants' balance, measures of mobility, ...
Cached Medicine News:Health News:Re –growing Brain cells destroyed by Parkinson’s disease 2Health News:Possible location of lung cancer genes found 2Health News:Cobblestone Walking May Be The Key For Healthy Living. 2
(Date:7/31/2015)... SAN DIEGO , July 31, 2015 ... Eisai Co., Ltd. (Headquarters: Tokyo , ... Halozyme Therapeutics, Inc. (Headquarters: San Diego, California ... , "NASDAQ: HALO") have signed a clinical collaboration agreement ... , "eribulin") in combination with Halozyme,s investigational drug PEGPH20 ...
(Date:7/31/2015)... HYDERABAD, India , July 31, 2015 /PRNewswire/ ... Billing and CRM solutions for video, data and cloud ... (PoC) with a leading pharma giant for Internet ... managing different IoT applications offered on subscription model. ... Pharma giant is striving for business ...
(Date:7/30/2015)... 30, 2015  ResMed (NYSE: RMD ... definitive agreement to acquire Curative Medical, a ... sleep-disordered breathing medical devices and accessories. ... with ResMed,s global leadership in sleep and respiratory medicine, ... China suffering from sleep-disordered breathing ...
Breaking Medicine Technology:Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 2Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 3Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 4Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 5Eisai and Halozyme Sign Collaboration Agreement to Investigate Eribulin and PEGPH20 in Metastatic Breast Cancer 6Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... Void in the Local Treatment of Oral Candidiasis in Immunosuppressed ... PLAINSBORO, N.J., Dec. 5 RHEI Pharmaceuticals, Inc. today announced ... antifungal with low dose miconazole in a patented mucoadhesive system, ... last clinical trial conducted for submission of the New Drug ...
... PARK, Calif., Dec. 4 Long-term data published ... Vale Area (MVA),after repair with the MitraClip(R) system ... clinically significant mitral stenosis. Additionally,with two years of ... system required surgery for mitral stenosis. At 12 ...
Cached Medicine Technology:RHEI Pharmaceuticals Announces the Initiation of the Final Clinical Study for Approval of Tibozole in China 2Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System 2Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System 3Two-Year Follow-Up Data Demonstrates Preservation of Adequate Mitral Valve Area in Patients Treated with the MitraClip(R) System 4
Solid 14 mm free-swinging blades, suture posts, and stabilizing disk. Dull finish....
Double bent ends prevent wire from catching when pushed forward. Designed for use with the Castroviejo Snare (E3675). Package of 12 stainless steel wires. Overall length 4.3 inches....
... to be used only with the E3671 twisted ... turning the wing nut and the loop can ... by ratchet so that the loop can be ... Overall length - 5.6 inches. Comes with one ...
Pediatric size. Loops retract lids. Polished finish....
Medicine Products: