Navigation Links
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says
Date:8/5/2014

TUESDAY, Aug. 5, 2014 (HealthDay News) -- Enriching the feeding-tube nutrition of intensive care patients on ventilators with agents that boost the immune system might cause more harm than good, researchers say.

This type of supplementation doesn't reduce risk of infection and could be associated with a higher risk of death, the researchers reported in the Aug. 6 issue of the Journal of the American Medical Association.

"These findings do not support the use of high-protein enteral nutrition [via feeding tube] enriched with immune-modulating nutrients in these patients," the study's authors wrote.

The results from this and other studies should discourage routine prescription of immunonutrition for critically ill patients outside the scope of well-designed randomized clinical trials, Dr. Todd Rice, of the Vanderbilt University School of Medicine, Nashville, Tenn., said in an accompanying journal editorial.

Some previous studies suggested that providing ICU patients with immune system-boosting nutrients, such as glutamine and omega-3 fatty acids, through feeding tubes is linked with fewer infections and faster recovery from critical illness compared with standard nutrition. But these findings remain the subject of debate among doctors.

To further investigate this issue, the researchers randomly assigned 301 adult ICU patients who were expected to need a feeding tube and a ventilator for more than 72 hours either the immune-boosting nutrients or standard high-protein nutrition. The patients received care in 14 different ICUs in the Netherlands, Germany, France and Belgium. Immune-boosting nutrition was given to half the patients, and the others received the standard nutrition. Patients were followed for up to six months.

The study revealed similar rates of new infections in the two groups -- 53 percent who got immune-boosting nutrition had new infections, compared to 52 percent in the standard nutrition group. The type of nutrition the patients received didn't affect the amount of time spent on a ventilator, a specific measure of organ failure, or how long they stayed in the ICU. Their nutrition also did not affect the length of their overall hospital stay.

However, the six-month death rate was higher (54 percent) in the patients that received the immune-boosting nutrition than those who had standard nutrition (35 percent). Although they couldn't prove a direct cause-and-effect relationship, the researchers concluded the additional nutrients that affect the immune system were associated with an increased risk of death at six months.

In his editorial, Rice noted that many questions about immune-boosting nutrition are still unanswered, including whether any single nutrient can help certain patients. How these nutrients are given to patients (via feeding tube or IV) may also affect how they work, he added.

More information

The U.S. National Institutes of Health provides more information on nutritional support.

SOURCE: JAMA, news release, Aug. 5 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
3. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
4. Study finds doctors have exaggerated fears when starting patients on insulin
5. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
6. Predictors identified for rehospitalization among post-acute stroke patients
7. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
8. Breast cancer patients suffer treatment-related side effects long after completing care
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Gastro Woes Often Strike Rheumatoid Arthritis Patients
11. Short Walks May Ease Fatigue in Pancreatic Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says
(Date:2/24/2017)... ... February 24, 2017 , ... An in-depth computational analysis of ... of Pittsburgh points to eight genes that may explain why susceptibility to one of ... results of a study published today in the journal npj Schizophrenia. , “There ...
(Date:2/24/2017)... ... February 24, 2017 , ... Healthcare Associates of ... Center at Craig Ranch building at 8080 State Highway 121, Suite 210, McKinney, Texas ... easy access to Highway 121. , As the practice has grown, the need for ...
(Date:2/24/2017)... ... February 24, 2017 , ... The International Association of Eating Disorders Professionals ... What You See” body image mannequin art competition. Selected from 15 submissions from around ... winner revealed at the 31st annual iaedp Symposium, March 22 – 26 in Las ...
(Date:2/24/2017)... ... February 24, 2017 , ... ... again hosted their Military Wedding Giveaway, with the winning couple announced on Feb. ... with services generously donated from local vendors: A Matter of Taste, Ryan Rousseau ...
(Date:2/23/2017)... , ... February 23, 2017 , ... ... with a clinician-based audience, will be participating in Rare Disease Day events, hosted ... D.C. In addition, Rare Disease Report, a website, weekly e-newsletter and quarterly publication, ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... 23, 2017 Research and Markets has announced ... and Strategies - 2016" report to their offering. ... The latest research Autism ... pricing data and benchmarks in the global Autism Spectrum Disorder market. ... What are the key drugs marketed for Autism Spectrum Disorder ...
(Date:2/23/2017)... Limited, ( ASX: ITD ), an innovative diversified healthcare company, is ... December 2016 compared with the previous corresponding period. A full "Results ... . Highlights Profit after ... Earnings per share of 2.2 cents (Dec 2015: 1.2 cents; up ... 11%) Profit before tax of $2.12m (Dec 2015: ...
(Date:2/23/2017)... -- Research and Markets has announced the addition of ... report to their offering. ... The latest research Oesophageal Cancer Drugs Price Analysis ... the global Oesophageal Cancer market. The research answers the ... drugs marketed for Oesophageal Cancer and their clinical attributes? How are ...
Breaking Medicine Technology: