Navigation Links
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says

TUESDAY, Aug. 5, 2014 (HealthDay News) -- Enriching the feeding-tube nutrition of intensive care patients on ventilators with agents that boost the immune system might cause more harm than good, researchers say.

This type of supplementation doesn't reduce risk of infection and could be associated with a higher risk of death, the researchers reported in the Aug. 6 issue of the Journal of the American Medical Association.

"These findings do not support the use of high-protein enteral nutrition [via feeding tube] enriched with immune-modulating nutrients in these patients," the study's authors wrote.

The results from this and other studies should discourage routine prescription of immunonutrition for critically ill patients outside the scope of well-designed randomized clinical trials, Dr. Todd Rice, of the Vanderbilt University School of Medicine, Nashville, Tenn., said in an accompanying journal editorial.

Some previous studies suggested that providing ICU patients with immune system-boosting nutrients, such as glutamine and omega-3 fatty acids, through feeding tubes is linked with fewer infections and faster recovery from critical illness compared with standard nutrition. But these findings remain the subject of debate among doctors.

To further investigate this issue, the researchers randomly assigned 301 adult ICU patients who were expected to need a feeding tube and a ventilator for more than 72 hours either the immune-boosting nutrients or standard high-protein nutrition. The patients received care in 14 different ICUs in the Netherlands, Germany, France and Belgium. Immune-boosting nutrition was given to half the patients, and the others received the standard nutrition. Patients were followed for up to six months.

The study revealed similar rates of new infections in the two groups -- 53 percent who got immune-boosting nutrition had new infections, compared to 52 percent in the standard nutrition group. The type of nutrition the patients received didn't affect the amount of time spent on a ventilator, a specific measure of organ failure, or how long they stayed in the ICU. Their nutrition also did not affect the length of their overall hospital stay.

However, the six-month death rate was higher (54 percent) in the patients that received the immune-boosting nutrition than those who had standard nutrition (35 percent). Although they couldn't prove a direct cause-and-effect relationship, the researchers concluded the additional nutrients that affect the immune system were associated with an increased risk of death at six months.

In his editorial, Rice noted that many questions about immune-boosting nutrition are still unanswered, including whether any single nutrient can help certain patients. How these nutrients are given to patients (via feeding tube or IV) may also affect how they work, he added.

More information

The U.S. National Institutes of Health provides more information on nutritional support.

SOURCE: JAMA, news release, Aug. 5 2014


Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
3. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
4. Study finds doctors have exaggerated fears when starting patients on insulin
5. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
6. Predictors identified for rehospitalization among post-acute stroke patients
7. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
8. Breast cancer patients suffer treatment-related side effects long after completing care
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Gastro Woes Often Strike Rheumatoid Arthritis Patients
11. Short Walks May Ease Fatigue in Pancreatic Cancer Patients
Post Your Comments:
Related Image:
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says
(Date:11/25/2015)... ... November 25, 2015 , ... TyloHelo Inc , North ... , Sauna accessories help improve the bather experience in the sauna, and the ... for the purist looking for simplicity in design to accessories that encourage a ...
(Date:11/25/2015)... Rouge, LA (PRWEB) , ... November 25, 2015 , ... ... in the United States District Court of Connecticut on behalf of a home health ... behalf of all current or former home health care workers employed by Humana, Inc., ...
(Date:11/25/2015)... FL (PRWEB) , ... November 25, 2015 , ... ... center, is encouraging people across the country to celebrate their sobriety and show ... people to post “before and after” photos this Thanksgiving with the hashtag #FacesOfGratitude ...
(Date:11/25/2015)... ... November 25, 2015 , ... Wimbledon Health Partners, the ... Wimbledon Athletics Facebook page to educate the public, parents and school ... About 2,000 people under the age of 25 die from sudden cardiac arrest ...
(Date:11/25/2015)... ... 2015 , ... Smiles by Stevens is pleased to announce the ... While many patients are aware of the benefits of Botox® in the treatment of ... suffering with discomfort, soreness, and pain as a result of Jaw Tension, TMJ (temporo-mandibular ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... -- Linden Care, LLC, a retail specialty pharmacy focused on ... from chronic pain, said today that it is disappointed ... enjoining Express Scripts from unilaterally terminating the Pharmacy Provider ... --> The company said that it ... --> --> In the ...
(Date:11/25/2015)... Nov. 25, 2015 On Tuesday, November ... bellwether trial against Wright Medical Technology, Inc. for ... Conserve metal-on-metal hip implant device, awarded $11 million ... two week trial and three days of deliberations, ... device was defectively designed and unreasonably dangerous, and ...
(Date:11/25/2015)... -- Henry Schein, Inc., the world,s largest provider of health ... animal health practitioners, will unveil at the Greater New ... Pavilion , which brings together for the first time ... help any practice or laboratory enter the digital age. ... of experts appearing at the Pavilion. --> ...
Breaking Medicine Technology: