Navigation Links
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says
Date:8/5/2014

TUESDAY, Aug. 5, 2014 (HealthDay News) -- Enriching the feeding-tube nutrition of intensive care patients on ventilators with agents that boost the immune system might cause more harm than good, researchers say.

This type of supplementation doesn't reduce risk of infection and could be associated with a higher risk of death, the researchers reported in the Aug. 6 issue of the Journal of the American Medical Association.

"These findings do not support the use of high-protein enteral nutrition [via feeding tube] enriched with immune-modulating nutrients in these patients," the study's authors wrote.

The results from this and other studies should discourage routine prescription of immunonutrition for critically ill patients outside the scope of well-designed randomized clinical trials, Dr. Todd Rice, of the Vanderbilt University School of Medicine, Nashville, Tenn., said in an accompanying journal editorial.

Some previous studies suggested that providing ICU patients with immune system-boosting nutrients, such as glutamine and omega-3 fatty acids, through feeding tubes is linked with fewer infections and faster recovery from critical illness compared with standard nutrition. But these findings remain the subject of debate among doctors.

To further investigate this issue, the researchers randomly assigned 301 adult ICU patients who were expected to need a feeding tube and a ventilator for more than 72 hours either the immune-boosting nutrients or standard high-protein nutrition. The patients received care in 14 different ICUs in the Netherlands, Germany, France and Belgium. Immune-boosting nutrition was given to half the patients, and the others received the standard nutrition. Patients were followed for up to six months.

The study revealed similar rates of new infections in the two groups -- 53 percent who got immune-boosting nutrition had new infections, compared to 52 percent in the standard nutrition group. The type of nutrition the patients received didn't affect the amount of time spent on a ventilator, a specific measure of organ failure, or how long they stayed in the ICU. Their nutrition also did not affect the length of their overall hospital stay.

However, the six-month death rate was higher (54 percent) in the patients that received the immune-boosting nutrition than those who had standard nutrition (35 percent). Although they couldn't prove a direct cause-and-effect relationship, the researchers concluded the additional nutrients that affect the immune system were associated with an increased risk of death at six months.

In his editorial, Rice noted that many questions about immune-boosting nutrition are still unanswered, including whether any single nutrient can help certain patients. How these nutrients are given to patients (via feeding tube or IV) may also affect how they work, he added.

More information

The U.S. National Institutes of Health provides more information on nutritional support.

SOURCE: JAMA, news release, Aug. 5 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
3. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
4. Study finds doctors have exaggerated fears when starting patients on insulin
5. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
6. Predictors identified for rehospitalization among post-acute stroke patients
7. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
8. Breast cancer patients suffer treatment-related side effects long after completing care
9. Heart failure patients with diabetes may benefit from higher glucose levels
10. Gastro Woes Often Strike Rheumatoid Arthritis Patients
11. Short Walks May Ease Fatigue in Pancreatic Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Immunonutrition' Ill-Advised for ICU Patients on Feeding Tube, Study Says
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... ... Haute Living, is proud to recognize Dr. Barry M. Weintraub as a prominent ... “the most beautiful women in the world, and the most handsome men, look ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th ... Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised ... have been wounded in battle and their families. Venture Construction Group is a 2016 ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
Breaking Medicine Technology: