Navigation Links
Immunology expert at Children's Hospital receives APS prize for patient-oriented research
Date:11/19/2009

A pediatric immunologist at The Children's Hospital of Philadelphia has received a prestigious annual award from the American Philosophical Society, an organization founded in 1743 by Benjamin Franklin. Jordan S. Orange, M.D., Ph.D., received the Society's Judson Daland Prize on Nov. 13 for his contributions to research and treatment of inherited immune deficiency diseases.

The Judson Daland Prize for Clinical Investigation recognizes outstanding achievements in patient-oriented research. Honorees are nominated by chairs of clinical departments at a U.S. medical school or hospital and selected by a distinguished committee of biomedical researchers.

Dr. Orange's work involves the innate immune system, the body's first defense against life-threatening infections and diseases. His particular research focus is natural killer cells, a major component of the innate immune system, which have an inherent ability to destroy cancer or virus-infected cells. While in graduate school at Brown University, he discovered that natural killer cells produce cytokines, which are secreted immune signaling molecules, to participate in defending the body against viruses.

Dr. Orange has continued his research in natural killer cells as a pediatrician, defining the field of human diseases caused by inherent deficiencies of natural killer cells. These include diseases in which only natural killer cells are defective, or where they are defective along with other components of immunity.

One example is Wiskott-Aldrich syndrome, a difficult to treat, life-threatening, immune-deficiency disease. Dr. Orange discovered a natural killer cell defect and its mechanism in these patients, which make them especially vulnerable to herpesvirus infections and blood cell cancers. He used this knowledge to develop a novel therapy that bypasses the cellular defect, and has begun a unique clinical trial of the treatment at The Children's Hospital of Philadelphia.

In addition to his laboratory research at Children's Hospital, Dr. Orange evaluates and cares for children with primary immunodeficiency diseases, a varied and complex group of disorders resulting from a congenital defect in some component of the immune system. Though it results in recurrent or severe infections, the child's underlying disease may go undiscovered for years until he or she receives an accurate diagnosis and appropriate treatment. Establishing an accurate diagnosis and providing therapy can dramatically improve outcome in these diseases and often provides a child with a relatively normal childhood and adult life.

Dr. Orange received the Daland Prize, including a $10,000 honorarium, during an award presentation on Nov. 13, at the American Philosophical Society's headquarters in center city Philadelphia. The prize commemorates Judson Daland, a prominent Philadelphia physician and medical researcher, who left a bequest to the Society to support clinical research. As part of that fund, the Society has awarded Judson Daland Fellowships since 1938, and established the annual prize in 2001.


'/>"/>

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia
Source:Eurekalert  

Related medicine news :

1. MedImmune Announces Winners of the 4th Respiratory, Immunology and Autoimmunity Research Abstract Competition
2. NIAID announces new human immunology research awards to help fight emerging infectious diseases
3. Karmanos Cancer Institute Immunology Researcher Obtains Nearly $1 Million National Institutes of Health Grant
4. New Federal Training Grant to Teach Doctors/Scientists Immunology
5. Immunology Center will continue to drive standard methods, better science
6. A*STARs Singapore Immunology Network Is the First GeneGo Center of Excellence in Asia
7. Nations top experts in psychoneuroimmunology to gather Sept 18-21 in Tampa, Fla.
8. The Journal of Allergy and Clinical Immunology devotes special issue to AIDS
9. CEL-SCI Presents Favorable Data for Leaps Vaccine Technology at Prestigious Immunology Conference
10. World-Renowned Scientists to Lead Immunology Course
11. Menopausal Women May Have an Increased Asthma Risk, From The Journal of Allergy and Clinical Immunology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immunology expert at Children's Hospital receives APS prize for patient-oriented research
(Date:12/2/2016)... ... December 02, 2016 , ... ... launch of its 60-day free trial program for all of the company’s desktop ... offer a truly hassle free experience. , FlexiSpot’s unique desktop risers use an ...
(Date:12/2/2016)... NY (PRWEB) , ... December 02, 2016 , ... U.S. ... exclusive interview with Mediaplanet, Dr. Murthy explains how he was inspired to practice medicine ... I learned that medicine is about more than making diagnoses and prescribing medicine,” he ...
(Date:12/2/2016)... CA (PRWEB) , ... December 02, 2016 , ... ... surgeon in Beverly Hills, California, will be included in the 2016 “Guide to ... to exceptional professionals based on the amalgamation of their education, experience, and professional ...
(Date:12/2/2016)... Delaware (PRWEB) , ... December 02, 2016 , ... ... released a new version of its SaaS LIMS, CloudLIMS Lite. CloudLIMS Lite helps ... sample entry through labeling, storing, shipping and disposal. The new version is a ...
(Date:12/2/2016)... ... December 02, 2016 , ... Sourced from the Isbre Springs beneath ... including its unmatched natural purity of just 6 ppm TDS (Total Dissolved Solids) in ... Water has been available in several ShopRite and FoodTown stores in NJ and received ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , December 2, 2016 ... "In Vitro Diagnostics/IVD Market by Product (Instruments, Reagents, ... Application (Diabetes, Oncology, Cardiology, Nephrology, Infectious Diseases) - ... market is valued at USD 60.22 Billion in ... a CAGR of 5.5% during the forecast period ...
(Date:12/2/2016)... 2016  The Addiction Treatment Advisory Group (ATAG), ... Care Pharmacy (AMCP), has released detailed findings on ... opioid addiction crisis, including through improved access to ... ATAG,s newly released paper, "The Role of Managed ... many issues around gaps and barriers to addiction ...
(Date:12/2/2016)... Dec. 2, 2016 Boston Scientific Corporation (NYSE: ... to acquire certain manufacturing assets and capabilities of the ... advanced biological tissue business, as well as a 15% ... million in cash. The Neovasc advanced biological tissue business ... Boston Scientific Lotus™ Valve System. * Upon completion ...
Breaking Medicine Technology: