Navigation Links
Immunology expert at Children's Hospital receives APS prize for patient-oriented research
Date:11/19/2009

A pediatric immunologist at The Children's Hospital of Philadelphia has received a prestigious annual award from the American Philosophical Society, an organization founded in 1743 by Benjamin Franklin. Jordan S. Orange, M.D., Ph.D., received the Society's Judson Daland Prize on Nov. 13 for his contributions to research and treatment of inherited immune deficiency diseases.

The Judson Daland Prize for Clinical Investigation recognizes outstanding achievements in patient-oriented research. Honorees are nominated by chairs of clinical departments at a U.S. medical school or hospital and selected by a distinguished committee of biomedical researchers.

Dr. Orange's work involves the innate immune system, the body's first defense against life-threatening infections and diseases. His particular research focus is natural killer cells, a major component of the innate immune system, which have an inherent ability to destroy cancer or virus-infected cells. While in graduate school at Brown University, he discovered that natural killer cells produce cytokines, which are secreted immune signaling molecules, to participate in defending the body against viruses.

Dr. Orange has continued his research in natural killer cells as a pediatrician, defining the field of human diseases caused by inherent deficiencies of natural killer cells. These include diseases in which only natural killer cells are defective, or where they are defective along with other components of immunity.

One example is Wiskott-Aldrich syndrome, a difficult to treat, life-threatening, immune-deficiency disease. Dr. Orange discovered a natural killer cell defect and its mechanism in these patients, which make them especially vulnerable to herpesvirus infections and blood cell cancers. He used this knowledge to develop a novel therapy that bypasses the cellular defect, and has begun a unique clinical trial of the treatment at The Children's Hospital of Philadelphia.

In addition to his laboratory research at Children's Hospital, Dr. Orange evaluates and cares for children with primary immunodeficiency diseases, a varied and complex group of disorders resulting from a congenital defect in some component of the immune system. Though it results in recurrent or severe infections, the child's underlying disease may go undiscovered for years until he or she receives an accurate diagnosis and appropriate treatment. Establishing an accurate diagnosis and providing therapy can dramatically improve outcome in these diseases and often provides a child with a relatively normal childhood and adult life.

Dr. Orange received the Daland Prize, including a $10,000 honorarium, during an award presentation on Nov. 13, at the American Philosophical Society's headquarters in center city Philadelphia. The prize commemorates Judson Daland, a prominent Philadelphia physician and medical researcher, who left a bequest to the Society to support clinical research. As part of that fund, the Society has awarded Judson Daland Fellowships since 1938, and established the annual prize in 2001.


'/>"/>

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia
Source:Eurekalert  

Related medicine news :

1. MedImmune Announces Winners of the 4th Respiratory, Immunology and Autoimmunity Research Abstract Competition
2. NIAID announces new human immunology research awards to help fight emerging infectious diseases
3. Karmanos Cancer Institute Immunology Researcher Obtains Nearly $1 Million National Institutes of Health Grant
4. New Federal Training Grant to Teach Doctors/Scientists Immunology
5. Immunology Center will continue to drive standard methods, better science
6. A*STARs Singapore Immunology Network Is the First GeneGo Center of Excellence in Asia
7. Nations top experts in psychoneuroimmunology to gather Sept 18-21 in Tampa, Fla.
8. The Journal of Allergy and Clinical Immunology devotes special issue to AIDS
9. CEL-SCI Presents Favorable Data for Leaps Vaccine Technology at Prestigious Immunology Conference
10. World-Renowned Scientists to Lead Immunology Course
11. Menopausal Women May Have an Increased Asthma Risk, From The Journal of Allergy and Clinical Immunology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immunology expert at Children's Hospital receives APS prize for patient-oriented research
(Date:4/28/2016)... ... 2016 , ... Cosmetic Town, an online plastic surgery community, announces the relaunch ... recently revamped and upgraded to allow even more interaction between doctors and patients as ... According to the senior editor of Cosmetic Town, “We are excited that our ...
(Date:4/28/2016)... ... April 28, 2016 , ... Greener Hydroponics is now ... pots are frequently used by professional organic farmers and nurseries according to Sales Manager ... supply of fabric pots. Our goal is to offer wholesale level pricing and ultra-fast ...
(Date:4/28/2016)... ... April 28, 2016 , ... In 2011, TIME magazine named Herr the ... of biomechatronics, technology that marries human physiology with electromechanics. He continues that work as ... the Founder of BionX , a leader in the field of prosthetic devices. ...
(Date:4/28/2016)... ... April 28, 2016 , ... ... of enterprise Data Center Infrastructure Management solutions, announces today the availability of ... enhancements in the area of capacity management and optimization, providing new analytical ...
(Date:4/28/2016)... ... April 28, 2016 , ... One way to ignore solid evidence is ... true. But we toss the baby out with the bathwater when we ignore all ... identifying higher-quality studies and otherwise making better use of education policy research. , “When ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... le 27 Avril 2016 ... progressé de +5% sur le trimestre, soutenu par ... consommables  Croissance de +16% des ventes ... Mauna Kea Technologies (Euronext : MKEA, FR0010609263 ; OTCQX : ... laser, annonce aujourd,hui son chiffre d,affaires pour le ...
(Date:4/27/2016)... , April 27, 2016 Tie-up ... initiative to save newborns   ... women & newborns in collaboration with Breast Milk Foundation (BMF), ... first Pasteurized Human Milk Bank, ,Amaara, in Delhi-NCR today. This ... food source for infants and should be available to babies ...
(Date:4/27/2016)... FRANCISCO , April 27, 2016 ... reach over USD 2.14 billion by 2022, according ... Inc.       (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ... technological advancement affecting the efficiency and accuracy delivered ... the persistent demand for novel urinalysis instruments and ...
Breaking Medicine Technology: