Navigation Links
Immunologists identify biochemical signals that help immune cells remember how to fight infection
Date:5/27/2009

amos, student research assistant in immunology and the study's lead author. "It turns out that the IL-12 signal is really important in driving that immediate, or effector, immune response while interferon drives the development of long-term memory."

Past UT Southwestern studies have shown that the two cytokines work together in CD4+ T-cells to generate memory cells; the new research suggests that these molecules perform distinct roles in another type of immune cell called CD8+ T lymphocytes.

For these cells, whether they become killers or long-term memory cells depends upon which cytokine they respond to. Those that receive the IL-12 become killers while those that receive interferon alpha turn into long-term memory cells.

"Regardless of the precise mechanism, what we know now is that you can develop both long-term and immediate memory cells at the same time," Dr. Farrar said.

The next step, he said, is to identify pools of memory cells that "remember" specific pathogens in humans.

"There are some vaccines that are extremely effective, while others are only moderately effective," Dr. Farrar said. "If we can isolate pools of antigen-specific memory cells, we should be able to determine what it is about those pools of memory cells that is different between an extremely effective vaccine and one that's not so effective.

"If we can figure that out, then we can start to think about altering our approach to vaccinating based on the different type of microorganism that we're trying to vaccinate against," he said.


'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Queens immunologists find better way to boost the immune system
2. Minor league hockey players unable to identify concussion symptoms, study says
3. Pediatrician creates easier way to identify kids high BP
4. Researchers identify key proteins needed for ovulation
5. Scientists identify gene in breast cancer pathway
6. Researchers identify the gene responsible for a rare form of congenital anemia
7. For Alzheimers Disease, Surveyed Neurologists Identify a Therapys Effect on Cognitive Decline as the Attribute That Most Influences Their Prescribing Decisions
8. Researchers identify stroke predictors in black patients
9. Experienced Critical Care and ER Doctor Offers Tips to Prevent and Identify Swine Flu
10. MCG participating in national study to identify genetic variants in schizophrenia
11. Second look ultrasound: Effective MRI correlate for identifying incidental breast lesions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immunologists identify biochemical signals that help immune cells remember how to fight infection
(Date:7/10/2014)... as tempting as full-fat equivalents could be heading ... how proteins can replace fats without affecting foodstuffs, ... Engineering and Physical Sciences Research Council (EPSRC), a ... Edinburgh has produced modified proteins that easily break ... behaviour of fats during food manufacture. The proteins ...
(Date:7/9/2014)... 2014 -- The World Health Organization recommends that youth ... to vigorous physical activity (MVPA) each day. Studies ... during school hours. Therefore, it stands to reason ... MVPA. In a new study scheduled for publication ... that time spent outdoors after school was positively associated ...
(Date:7/9/2014)... Perelman School of Medicine at the University of Pennsylvania ... received an $8 million grant from the National Cancer ... therapy (PDT) in patients with malignant pleural mesothelioma, a ... itself in the lining of the lungs and is ... will fund a clinical trial and additional studies looking ...
(Date:7/9/2014)... Studying the most common type of lung cancer, researchers ... a role in forming tumors. The new knowledge may ... these genetic changes already are available or are in ... , investigators from The Cancer Genome Atlas (TCGA), including ... Louis, Harvard Medical School and other institutions, studied tumors ...
(Date:7/9/2014)... used in policing injection drug users in Russia ... , A study, conducted by researchers from ... in collaboration with St. Petersburg Pavlov State University, ... on the health outcomes of a cohort of ... , Those who were arrested by police were ...
Breaking Medicine News(10 mins):Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2Health News:Go play outside! Outdoor time promotes physical activity in youth 2Health News:Penn mesothelioma program receives $8 million NCI grant 2Health News:Lung cancer study hints at new treatments 2Health News:BU researchers relate arrests with HIV risk environment 2
... nutritional supplement used by weightlifters and sprinters to improve ... muscular dystrophies. ,Muscle strength increased by an ... to those who did not use the supplement, according ... gained an average of 1.4 pounds more lean body ...
... promise for people suffering from insomnia, particularly narcolepsy - a ... during waking hours.// ,The first phase of the ... 70 males for about 12 hours, who were healthy and ... ,They found that when orexin, a neuropeptide that ...
... can be used as an oral contraceptive for birth control ... and Drug Administration have formulated this drug especially for woman, ... dysphoric disorders. ,The YAZ drug, manufactured by Bayer ... by the FDA for three distinct uses. ,Phil ...
... life of common man. They are intended to boost the sale ... When it comes to promoting// drugs through commercials, the campaigns are ... don’t need them. ,This was revealed in a survey ... University of California – Los Angeles Department of Medicine. This group ...
... in at least ten districts of Nairobi. This was announced ... Munyao declared that 100,000 doses of vaccines are being distributed ... of insecticides have also been handed over to these places. ... due to RVF and four hundred cases are reported sick. ...
... ,The Canadian Football League linebacker and father of two, ... was infected with HIV while having sexual relationships with two ... with the court, Smith tested HIV positive and was informed ... asked to inform his sexual partners about this and to ...
Cached Medicine News:Health News:Creatine Supplement May Help People With Muscular Dystrophies 2
(Date:1/15/2014)...  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has announced the ... Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) ... in order to treat dental impairments, for tooth restoration ...
(Date:1/15/2014)... 2014 Massachusetts General Hospital (MGH), the Broad ... announced today that they have launched a strategic ... targets and develop novel therapies for inflammatory bowel ... worldwide. The MGH-Broad-Amgen collaboration brings together scientists with ...
(Date:1/15/2014)... Fla. , Jan. 15, 2014  In an unprecedented effort to ... TB in ambulances and other transport vehicles, an advanced and portable ... rescue personnel for the first time. In order ... with these deadly pathogens, West Palm Beach ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Superbugs No Longer Ride In Rescue Vehicles 2
... , April 26 e-MDs, an industry leader ... and practice management (PM) solutions, announced they have been selected ... Alaska EHR Alliance (AEHRA).   e-MDs was identified through ... Alaska healthcare providers looking to incorporate an EHR in ...
... 26 Sirion Therapeutics, Inc., a privately held ophthalmic ... is now commercially available.  Zirgan™, which was approved by the ... is a topical ophthalmic antiviral indicated for the treatment of ... , , ...
Cached Medicine Technology:Alaska EHR Alliance Selects e-MDs as Recommended Electronic Health Record Vendor 2Alaska EHR Alliance Selects e-MDs as Recommended Electronic Health Record Vendor 3Alaska EHR Alliance Selects e-MDs as Recommended Electronic Health Record Vendor 4Sirion Therapeutics Announces Availability of Zirgan(TM) (ganciclovir ophthalmic gel) 0.15% for Ocular Herpes 2Sirion Therapeutics Announces Availability of Zirgan(TM) (ganciclovir ophthalmic gel) 0.15% for Ocular Herpes 3
Mac Pherson titanium tying forceps are ergonomic, very thin, angled with tying platforms. Round ergonomic design for great balance and feel. Fine platforms excellent for tying 10-0 suture....
Fine tying forceps, standard with smooth jaws. For 7-0 to 9-0 sutures....
Harms tying forceps, standard, straight with smooth jaws. For 7-0 to 9-0 sutures....
Tennant stainless steel tying forceps is extra delicate, straight with smooth jaws, 6 mm long platform, round handle with guide pin. For 9-0 to 11-0 sutures....
Medicine Products: