Navigation Links
Immunoglobulin Can Predict Some Diabetic Complications

Increased excretion of IgM foretells serious cardiovascular issues: study

FRIDAY, Aug. 7 (HealthDay News) -- Swedish researchers say that immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage caused by diabetes.

The study included 139 patients who were followed from 1984 to 2007. Those with increased levels of IgM in their urine at the start of the study were about three times more likely to suffer cardiovascular-related death or to progress to end-stage kidney disease.

The study appears in the journal BMC Medicine.

"To our knowledge, this is the first study to investigate the impact of increased urine IgM excretion on DN disease progression in type 1 diabetes patients," lead researcher Dr. Omran Bakoush of Lund University said in a news release. "We found that those with increased urinary IgM excretion had a higher mortality from cardiovascular causes and higher disease progression rate to end-stage renal disease. This association is largely independent of the level of albuminuria."

Bakoush said the "findings may offer a new approach to manage this rapidly increasing patient population. While measurement of albuminuria is routinely used to evaluate and manage patients with diabetes, increased urine IgM excretion would identify more specifically patients at risk for serious cardiovascular complications (death and renal failure). If increased urine IgM excretion does reflect advanced atherosclerotic vascular disease, clinical trials would be justified to test whether modifying atherosclerotic factors also decrease mortality and incidence of renal failure in diabetic patients with or without IgM-uria."

More information

The MedlinePlus Medical Encyclopedia has more about diabetic nephropathy.

-- Robert Preidt

SOURCE: BioMed Central, news release, Aug. 3, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Sex Hormone Protein May Predict Type 2 Diabetes
2. Brain Scan May Help Predict Cancer Drug Response
3. Biomarker Could Predict Severe Osteoarthritis
4. Obama White House Can Save $3.7 Trillion and Extend Lifespan 29+ Years, Predicts Revolutionary A4M Healthcare Plan
5. Protein level may serve as predictor of severe osteoarthritis
6. Mathematical modeling predicts response to Herceptin
7. Heart Surgeon Shortage Predicted
8. Is somatic hypersensitivity a predictor of irritable bowel syndrome?
9. Biomarkers May Predict Alzheimers
10. Test May Predict Moms Who Will Deliver Prematurely
11. Reed Group Will Debut New Predictive Modeling Tool at DMEC Conference
Post Your Comments:
Related Image:
Immunoglobulin Can Predict Some Diabetic Complications
(Date:6/27/2016)... Viejo, California (PRWEB) , ... June 27, 2016 , ... ... are fully customizable inside of Final Cut Pro X," said Christina Austin - CEO ... another unique style. Final Cut Pro X users can now reveal the ...
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... , ... June 26, 2016 , ... On June 10-11, ... of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, ... the city’s history as home to some of the world’s leading providers of cereal ...
(Date:6/26/2016)... NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and ... to be personalized through a fitness app. The fitness app plans to fix the two ... currently only offer a one size fits all type program , They don’t ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Bay Area ... Network,s Dean Center for Tick Borne Illness ... and Rehabilitation, MIT Hacking Medicine, University of California, ... today announced the five finalists of Lyme ... disease.  More than 100 scientists, clinicians, researchers, entrepreneurs, ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
Breaking Medicine Technology: