Navigation Links
Immune system to fight brain tumors
Date:5/30/2013

Research at Lund University in Sweden gives hope that one of the most serious types of brain tumour, glioblastoma multiforme, could be fought by the patients' own immune system. The tumours are difficult to remove with surgery because the tumour cells grow into the surrounding healthy brain tissue. A patient with the disease therefore does not usually survive much longer than a year after the discovery of the tumour.

The team has tested different ways of stimulating the immune system, suppressed by the tumour, with a 'vaccine'. The vaccine is based on tumour cells that have been genetically modified to start producing substances that activate the immune system. The modified tumour cells (irradiated so that they cannot divide and spread the disease) have been combined with other substances that form part of the body's immune system.

The treatment has produced good results in animal experiments: 75 per cent of the rats that received the treatment were completely cured of their brain tumours.

"Human biology is more complicated, so we perhaps cannot expect such good results in patients. However, bearing in mind the poor prognosis patients receive today, all progress is important", said doctoral student Sara Fritzell, part of the research group led by consultant Peter Siesj.

She has previously tested combining the activation of the immune system with chemotherapy. When the chemotherapy was applied directly to the tumour site, the positive effects reinforced each other, and a huge 83 per cent of the mice survived.

"Our idea is in the future to give patients chemotherapy locally in conjunction with the operation to remove as much of the tumour as possible", said Sara Fritzell.

Peter Siesj is currently applying for permission to carry out a clinical study on stimulation of the immune system with or without local chemotherapy as a treatment for patients with glioblastoma multiforme.


'/>"/>

Contact: Sara Fritzell
sara.fritzell@med.lu.se
46-462-228-585
Lund University
Source:Eurekalert

Page: 1

Related medicine news :

1. Discarded immune cells induce the relocation of stem cells
2. New Drug May Help Immune System Fight Cancer
3. Your immune system: On surveillance in the war against cancer
4. Immune Cell Discovery May One Day Lead to Herpes Vaccine: Study
5. Temple scientists weaken HIV infection in immune cells using synthetic agents
6. Estrogen fuels autoimmune liver damage
7. New findings on the brains immune cells during Alzheimers disease progression
8. Current HPV vaccine may not help some women with immune problems
9. UCLA, Caltech research on immune-cell therapy could strengthen promising melanoma treatment
10. Immune Therapy Shows Early Promise for Advanced Leukemia
11. Study reveals potential immune benefits of vitamin D supplements in healthy individuals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... Viejo, California (PRWEB) , ... January 20, 2017 , ... ... easy to use inside of Final Cut Pro X," said Christina Austin - CEO ... on the RED Dragon. Utilizing the Dragon Sensor,TransFlare 4K Mystique lens flare and light ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Mary Magdalene: Grace is Greater than ... the woman who witnessed Jesus Christ firsthand. “Mary Magdalene: Grace is Greater than Sin” ... career as an educator interacting with countless women who had little knowledge of the ...
(Date:1/20/2017)... ... , ... “Code Word: Chocolate Biscuit”: a biographical account following a man who went on to ... published author, Marlyn Ivey, born in Lynn Haven, Florida and at the age of 5, ... years of age, he joined the Navy and got married right out of boot camp. ...
(Date:1/20/2017)... , ... January 20, 2017 , ... ... ® Oscillating Positive Expiratory Pressure (OPEP) device, was featured in a study indicating ... Pursley, MEd, RRT-ACCS, FAARC, “Analysis of Three Oscillating Positive Expiratory Pressure Devices ...
(Date:1/20/2017)... ... ... “Journey to Christmas:” a beautiful and enchanting tale that teaches children the true meaning of ... three in Oklahoma City, and a devoted woman of faith. , “Becoming a parent ... the back of my mind for years, but actually doing it might have been a ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Conference Call and Webcast to ... ) today announced it will release results for the fourth quarter ... ... host a conference call at 4:30 PM ET on Wednesday, February ... full year 2016 financial results and other corporate activities. To participate ...
(Date:1/19/2017)... , Jan. 19, 2017 This report ... current and future scenario of the global market. Large ... opioid consumption. Severe chronic constipation is a major side ... traditional laxatives. Hence, novel targeted therapy has been prescribed ... sufferers, launch of targeted medicines, and growing awareness about ...
(Date:1/19/2017)...  Stealth BioTherapeutics Inc. ( Stealth ), a clinical-stage ... announced new additions to its senior leadership team: ... and Daniel Geffken as interim Chief Financial ... , Pharm.D. has been promoted to Chief Clinical Development ... Doug and Daniel to our management team, as both ...
Breaking Medicine Technology: