Navigation Links
Immune system to fight brain tumors
Date:5/30/2013

Research at Lund University in Sweden gives hope that one of the most serious types of brain tumour, glioblastoma multiforme, could be fought by the patients' own immune system. The tumours are difficult to remove with surgery because the tumour cells grow into the surrounding healthy brain tissue. A patient with the disease therefore does not usually survive much longer than a year after the discovery of the tumour.

The team has tested different ways of stimulating the immune system, suppressed by the tumour, with a 'vaccine'. The vaccine is based on tumour cells that have been genetically modified to start producing substances that activate the immune system. The modified tumour cells (irradiated so that they cannot divide and spread the disease) have been combined with other substances that form part of the body's immune system.

The treatment has produced good results in animal experiments: 75 per cent of the rats that received the treatment were completely cured of their brain tumours.

"Human biology is more complicated, so we perhaps cannot expect such good results in patients. However, bearing in mind the poor prognosis patients receive today, all progress is important", said doctoral student Sara Fritzell, part of the research group led by consultant Peter Siesj.

She has previously tested combining the activation of the immune system with chemotherapy. When the chemotherapy was applied directly to the tumour site, the positive effects reinforced each other, and a huge 83 per cent of the mice survived.

"Our idea is in the future to give patients chemotherapy locally in conjunction with the operation to remove as much of the tumour as possible", said Sara Fritzell.

Peter Siesj is currently applying for permission to carry out a clinical study on stimulation of the immune system with or without local chemotherapy as a treatment for patients with glioblastoma multiforme.


'/>"/>

Contact: Sara Fritzell
sara.fritzell@med.lu.se
46-462-228-585
Lund University
Source:Eurekalert

Page: 1

Related medicine news :

1. Discarded immune cells induce the relocation of stem cells
2. New Drug May Help Immune System Fight Cancer
3. Your immune system: On surveillance in the war against cancer
4. Immune Cell Discovery May One Day Lead to Herpes Vaccine: Study
5. Temple scientists weaken HIV infection in immune cells using synthetic agents
6. Estrogen fuels autoimmune liver damage
7. New findings on the brains immune cells during Alzheimers disease progression
8. Current HPV vaccine may not help some women with immune problems
9. UCLA, Caltech research on immune-cell therapy could strengthen promising melanoma treatment
10. Immune Therapy Shows Early Promise for Advanced Leukemia
11. Study reveals potential immune benefits of vitamin D supplements in healthy individuals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... health professionals, announced today its affiliation with Tennessee Counseling Association. This ... the network of the Tennessee Counseling Association, adding exclusive benefits and promotional offers. ...
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
(Date:6/24/2016)... KNOXVILLE, Tenn. , June 24, 2016 /PRNewswire/ ... market providing less invasive and more durable cerebrospinal ... million in funding.  The Series-A funding is led ... the Lighthouse Fund, and other private investors.  Arkis, ... less-invasive neurosurgical instrumentation and the market release of ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic ... Coating, Parenteral) - Global Forecast to 2021" report ... The global pharmaceutical excipients market is projected to ... of 6.1% in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: