Navigation Links
Immune responses to tetanus vaccine unchanged for RA patients on rituximab
Date:1/6/2010

ey received MTX alone or rituximab in combination with MTX.

Patients treated only with MTX had a greater response to the pneumonia vaccine compared with those also receiving rituximab. Researchers found that only 57% of patients treated with rituximab had a response to one type of pneumococcal vaccine (Pneumovax) compared with 82% of MTX-only patients.

The ability to maintain a positive delayed-type hypersensitivity (DTH) response to the Candida albicans skin test was comparable in both groups with 77.4% of rituximab-treated patients and 70% of MTX-only patients responding. "Our study, the first to examine DTH responses, confirmed that rituximab had no incremental effect on the patient's ability to mount a DTH response," said Dr. Bingham.

Treatment with rituximab produces a rapid depletion of B cells from the circulation, impacting the body's immune function. This depleted B cell pool begins to recover approximately 6-9 months after the initial treatment with rituximab. In his editorial also published in Arthritis & Rheumatism, E. William St. Clair, M.D. from Duke University Medical Center highlighted the need for further research into the effects of rituximab treatment.

"Further studies similar to Bingham et al are necessary to understand the complex effects of rituximab therapy on immune responses," noted Dr. St. Clair. "This study only evaluated immunization responses approximately 6 months after rituximab was administered; the responses at earlier time points, based on animal studies and its mechanism of action, may have been further attenuated," St. Clair added.


'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. Immune deficiency linked to a type of eye cancer
3. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
4. Melanoma drug revs immune cells but cancer cells ignore it
5. Study identifies key player in the bodys immune response to chronic stress
6. MedImmune Resolves FDA Observations Regarding Manufacturing Process for FluMist(R)
7. UVA researchers find important clue to immune infertility
8. M.D. Anderson-led team reports possible key to autoimmune disease
9. Their immune cells, fighting your cancer
10. MedImmune Licenses Reverse Genetics Technology to GlaxoSmithKline for Use in Influenza Vaccine Development and Production
11. Occupational exposures may be linked to death from autoimmune disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... Illinois (PRWEB) April 18, 2015 Heritage ... will begin its Supportive Living Week Celebration on April ... on having a healthy mind, body and soul. , ... in McLeansboro, Illinois, serves older adults of all incomes, ... maintain their independence. , Supportive Living Week is observed ...
(Date:4/17/2015)... Rosetta Radiology is proud to now offer ... of diagnostic imaging services. This solidifies them as a ... East Side of Manhattan. , The new imaging equipment ... of PET-CT, combined with Rosetta’s state of the art ... with patients through several stages of the cancer care ...
(Date:4/17/2015)... Riviera Magazine has featured board ... the Gallery of Cosmetic Surgery in Newport Beach, California ... The publication focused on his expertise in the lower ... eyelid surgery, laser resurfacing and rhinoplasty. , Dr. Sadati’s ... resulted in thousands of satisfied patients across the globe. ...
(Date:4/17/2015)... Tampa, Florida (PRWEB) April 17, 2015 ... Term Acute Care and Florida Hospital Carrollwood were all ... Hospital Wesley Chapel, located in Pasco County, is ranked ... Bay Times workplaces survey, which was conducted in partnership ... is an 83 all-private bed hospital that opened in ...
(Date:4/17/2015)... 17, 2015 From the day Dr. Todd ... Texas non-profit organization has empowered young people to create meaningful ... bring fresh water and the Gospel to all of ... Between March 17 and 27, students, faculty and staff raised ... with fresh water and the Good News of Jesus. ...
Breaking Medicine News(10 mins):Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4Health News:The Last Well and Liberty U’s TEN Initiative raises $21,000 to Bring Fresh Water & The Gospel to 7,000 Liberians 2
... cause malignancy, or just share common risk factors? , ... may have something else to be concerned about -- ... consensus report produced by experts recruited jointly by the ... , Diabetes, primarily type 2 diabetes, has been linked ...
... ... on the findings of the Griffin Inquiry into the E.Coli 0157 outbreak at Godstone farm in ... ... the findings of the Griffin Inquiry into the E.Coli 0157 outbreak at Godstone farm in August ...
... ... at Carefx.com/referralbrief and HFMA , June 20-23, Las Vegas (Booth #633). ... ... 2010 -- Carefx Corporation , a leading provider of interoperable workflow solutions, announced ...
... ... Dr. Baskaran Pillai, founder of the Center For Mind Science, presents the conference: Concepts ... of Cabo San Lucas, Mexico, participants will be guided on an intensive journey into the ... of the ancient yogis. , ...
... ... California family whose child is thriving in the special education system has ... through over protectiveness. This family is sharing their story of how they ... sight due to an extremely premature birth and its complications. They have ...
... consensus statement of experts assembled by the American ... emerging evidence that suggests cancer incidence is associated ... factors and treatments. The new report reviews the ... and cancer incidence/prognosis; risk factors common to both ...
Cached Medicine News:Health News:Scientists Tease Out Links Between Diabetes, Cancer 2Health News:Scientists Tease Out Links Between Diabetes, Cancer 3Health News:Jill Greenfield Comments on the Numerous Failings Highlighted by the Griffin Inquiry into Godstone Farm E.Coli 0157 Outbreak 2Health News:Jill Greenfield Comments on the Numerous Failings Highlighted by the Griffin Inquiry into Godstone Farm E.Coli 0157 Outbreak 3Health News:Jill Greenfield Comments on the Numerous Failings Highlighted by the Griffin Inquiry into Godstone Farm E.Coli 0157 Outbreak 4Health News:Electronic Referral Management Streamlines Referral Process and Boosts Provider Revenues, Says New Carefx Issue Brief 2Health News:Electronic Referral Management Streamlines Referral Process and Boosts Provider Revenues, Says New Carefx Issue Brief 3Health News:Dual Purpose Vacations Combine Yoga Spa Vacation in Cabo San Lucas, Mexico, With Authentic Yogic Miracles Conference 2Health News:California Family Raising Confident, Blind Child Sharing Successes to Change Perceptions of Blindness 2Health News:California Family Raising Confident, Blind Child Sharing Successes to Change Perceptions of Blindness 3Health News:California Family Raising Confident, Blind Child Sharing Successes to Change Perceptions of Blindness 4Health News:Experts explore emerging evidence linking diabetes and cancer 2Health News:Experts explore emerging evidence linking diabetes and cancer 3
(Date:4/17/2015)... April 17, 2015   IBA Molecular, a ... announced today that it has signed a definitive agreement ... Inc. (IBAM NA), to Illinois Health and Science (IHS). Under ... an independent company headquartered in Dulles, Virginia ... advantage of new product and footprint synergies. IBA Molecular ...
(Date:4/17/2015)... 17, 2015 Bionomics Limited (ASX:BNO, ADR:BMICY), a ... innovative therapeutics for the treatment of cancer and diseases ... of data from three of its most advanced oncology ... (AACR) 106 th Annual Meeting being held from ... USA. The presentation on the ...
(Date:4/16/2015)... April 16, 2015 A drug commonly taken to ... people with multiple sclerosis (MS), according to a study released ... Neurology,s 67th Annual Meeting in Washington, DC ... half of people with MS experience at some point in ... the nerve carrying vision from the eye to the brain ...
Breaking Medicine Technology:Health Care System to Acquire IBA Molecular North America 2Health Care System to Acquire IBA Molecular North America 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5Epilepsy Drug May Preserve Eyesight for People with MS 2
... CareFusion will showcase its full portfolio of ... American Society for Health-System Pharmacists (ASHP) Midyear Clinical Meeting ... (Logo: http://photos.prnewswire.com/prnh/20100706/CAREFUSIONLOGO ) "The ... than ever, technology solutions must help increase safety and ...
... 5, 2011 OrbusNeich today announced that data published in ... Genous Stent is safe when accompanied by only 10 days ... trial involving 49 patients treated with Genous, no patient had ... cardiac death, myocardial infarction or angiographic evidence of stent thrombosis ...
Cached Medicine Technology:CareFusion Showcases Medication Management Technologies at American Society for Health-System Pharmacists Conference 2CareFusion Showcases Medication Management Technologies at American Society for Health-System Pharmacists Conference 3Data Published in EuroIntervention Indicate that OrbusNeich's Genous™ Stent Is Safe with Very Short-Term Dual Antiplatelet Therapy 2Data Published in EuroIntervention Indicate that OrbusNeich's Genous™ Stent Is Safe with Very Short-Term Dual Antiplatelet Therapy 3
Illuminated Phoroptor Refracting Instrument. Illumination is provided by a cool-running, energy efficient LEDs (Light Emitting Diodes) that light only what you need to see without affecting the darke...
Double Maddox...
Maddox Rod, short handle (12cm)...
... The Snellen chart remains to most ... range of different optotypes can be ... sheridan-gardner, landolt Cs, tumbling Es and ... column can be shown and a ...
Medicine Products: