Navigation Links
Immune cells predict success of head and neck cancer treatment, U-M study finds
Date:4/26/2010

ANN ARBOR, Mich. Levels of a key type of immune cell are higher in head and neck cancer patients whose tumors are linked to the human papillomavirus, or HPV, according to researchers at the University of Michigan Comprehensive Cancer Center.

The finding suggests a way to predict which tumors are most likely to respond to chemotherapy and radiation and allow doctors to choose the best treatment option up front.

"In the past, we would give toxic chemotherapy to a patient, look at how the tumor responded and then decide whether the patient needed surgery or radiation. Now with patients who have HPV-positive cancers, this study suggests we can look in the microscope, measure the level of these immune cells and, based on that, select a treatment that is going to be potentially less toxic for the patient and most effective at curing the cancer," says study author Gregory T. Wolf, M.D., professor and chair emeritus of otolaryngology at the U-M Medical School.

Results of the study will be presented April 29 at the American Head and Neck Society annual meeting.

The researchers looked at 66 patients with oropharyngeal cancer, which includes cancers of the tonsils and the tongue base. They measured levels of several immune system cells in the blood and tracked HPV status.

The HPV-positive patients had higher levels of a subset of T-lymphocyte cells, a type of immune cell that is responsible for killing tumor cells. Patients who responded to an initial round of chemotherapy also had higher levels of these cells, while patients whose cancer recurred had lower levels.

"When we looked at how successful chemotherapy and radiation were, the levels of those killer T-lymphocyte cells predicted who was going to do well. That ability to predict response was even better than when we look at whether the tumors were HPV-positive or negative," says Wolf, director of the Head and Neck Cancer Specialized Program of Research
'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Skin Condition Vitiligo Tied to Immune System Dysfunction
2. Immune sensors suppress colitis-associated cancer
3. Tumors hide out from the immune system by mimicking lymph nodes
4. Tumors Use a Protein to Hide From Immune System
5. Optimism May Boost Immune System
6. Researchers discover fundamental step in immune-system development
7. Optimism boosts the immune system
8. Go with Your Gut and Boost your Immune System with America's Favorite Fruit
9. Study Details Machinery of Immune Protection Against Inflammatory Diseases Like Colitis
10. Targeting blood vessels, immune system may offer way to stop infection-caused inflammation
11. New approach to immune cell analysis seen as first step to better distinguish health and disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immune cells predict success of head and neck cancer treatment, U-M study finds
(Date:7/31/2014)... Longmont, Colo. (PRWEB) July 31, 2014 ... snacks, has launched three new products including: a Cacao Nib ... Like all Two Moms in the Raw products, each is ... , “My family is picky, so I’m constantly working on ... our consumers more healthy and tasty choices,” said Shari Leidich, ...
(Date:7/31/2014)... Ohio Presbyterian Retirement Services (OPRS) announced that ... Center, Inc. (Sarah Moore HCC) has joined its family ... Sarah Moore HCC was established in 1892 as a home ... has grown and developed an excellent reputation for high-quality assisted ... has been an integral part of the Delaware community for ...
(Date:7/31/2014)... Francsico, CA (PRWEB) July 31, 2014 ... Sweden have published the largest study ... triage through either teledermoscopy or traditional letter referral ... that smartphone referrals via patent pending iDoc24® technology ... patients with skin cancer while potentially eliminating unnecessary ...
(Date:7/31/2014)... Glaser Pediatric AIDS Foundation (EGPAF) and Riders for ... the delivery of laboratory samples and HIV-related test ... the Northern and Central Zones of Malawi. ... will establish a dependable and coordinated system to ... in health services for the more than 1.3 ...
(Date:7/31/2014)... Delhi, India (PRWEB) July 31, 2014 ... special service for those individuals and organizations against whom ... service as ‘Remove Negative Comments Service’. , About ... said, “We have officially announced the service now, but ... get rid of negative comments for several years.” , ...
Breaking Medicine News(10 mins):Health News:Two Moms in the Raw Launches Three New, Raw, Sprouted 100% Organic Snacks 2Health News:Two Moms in the Raw Launches Three New, Raw, Sprouted 100% Organic Snacks 3Health News:Ohio Presbyterian Retirement Services Welcomes The Sarah Moore HCC into Its Family 2Health News:Ohio Presbyterian Retirement Services Welcomes The Sarah Moore HCC into Its Family 3Health News:Smartphone iDoc 24 Technology Speeds Time to Diagnosis and Treatment for Skin Cancer Patients 2Health News:Smartphone iDoc 24 Technology Speeds Time to Diagnosis and Treatment for Skin Cancer Patients 3Health News:Smartphone iDoc 24 Technology Speeds Time to Diagnosis and Treatment for Skin Cancer Patients 4Health News:Elizabeth Glaser Pediatric AIDS Foundation partners with Riders for Health in Malawi 2Health News:RankingBySEO Launches a New Service ‘Remove Negative Comments’ 2
... must stop tippling if they want to recover from ... that researched the brain's capacity to regenerate.// ... provides evidence that excessive drinking for a long period ... portal EurekAlert. ,During abstinence, an alcoholic's brain ...
... and literature to spread awareness about the importance of ... including 6,000 women scholars, will be appointed to spread ... said Chaudhry Shahbaz Hussain, federal population planning minister. ... students also aware of these norms, he said. ...
... next-generation medical technology, in conjunction with MYOTECH//, LLC, ... the potential of the MYO-VAD, a cardiac support ... failure. The MYO-VAD restores cardiac output on an ... implanted in approximately three minutes. ,Researchers found ...
... Supermarket chains are recalling some brands of frozen ready meals ... Eye meals//, because of fears that they may contain small ... thousands of ready meals. ,The products came ... Group. Rye Valley foods are one of the country's biggest ...
... from the Italian court, presiding over a milestone case regarding ... paralyzed and terminally ill – who has petitioned the court ... and allow him to die. ,Italy, largely influenced ... and the case has stirred a hornet’s nest, where euthanasia ...
... cells have the ability to trace damaged tissue in the ... on mice.// ,This finding is of great interest ... the human brain, and this knowledge can be put to ... disorders such as traumatic injury. ,Dr. Chay Kuo, ...
Cached Medicine News:Health News:Positive Animal Study on MYO-VAD, Promise for Treatment of Heart Failure 2Health News:Stem Cells In Brain Have Potential For Sensing Damage And To Repair 2
(Date:7/31/2014)... July 31, 2014  Zacks.com announces the list of stocks ... Research analysts discuss the latest news and events impacting stocks ... include the Biogen (Nasdaq: BIIB - Free Report ), Gilead ... PBYI - Free Report ), AbbVie (NYSE: ABBV ... Free Report ). Today, Zacks is promoting its ...
(Date:7/31/2014)... YORK , July 31, 2014 TB ... better, faster and affordable treatments for tuberculosis (TB), announced ... Vice President, Market Access. Ms. Robertson joins the organization ... company,s business in Sub-Saharan Africa and Eastern ... oversee the TB Alliance,s efforts to ensure beneficial new ...
(Date:7/31/2014)... und KISSING, Deutschland, 31. Juli ... und Distributor eines computerunterstützten („robotischen") Koloskopie-Systems für ... (Homi) Shamir , ein weltweit anerkannter Manager ... und Kontrollgremiums zum Unternehmen stößt. ... Shamir ist ein hochangesehener globaler Visionär ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 2The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 3The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 4The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 5The Zacks Analyst Blog Highlights: Biogen, Gilead, Puma Biotechnology, AbbVie and Celgene 6TB Alliance Names Elana Robertson Senior Vice President, Market Access 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 3invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 2invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 3
... 4, 2011 Bioness Inc. today ... of the FASTEST study to further examine the impact of ... drop as a result of stroke. The FASTEST study aims ... System over standard therapy with an ankle-foot orthosis (AFO), and ...
... Inc. (NASDAQ: NBIX ) today announced that it ... for elagolix and next-generation Gonadotropin Releasing Hormone (GnRH) Receptor Antagonists. ... with the FDA, the outcome of which generated a $20 ... event brings the total milestones achieved by the Company in ...
Cached Medicine Technology:Bioness Inc. Announces Completion of Enrollment in Its FASTEST L300 Study 2Neurocrine Biosciences Receives Second Milestone Payment of $20 Million Under Abbott Collaboration Agreement 2
Hand surgery basic instrument set with round handled instruments...
Rhoton microscopic forceps, straight...
Quick release, easy to close 2" webbing and buckle. Available in teal, royal, red, purple, and maroon nylon stain-resistant fabric or navy nylon reinforced vinyl....
Velcro closures on each side to more evenly distribute the weight. Available in teal, royal, red, purple, or maroon nylon stain-resistant fabric or navy nylon reinforced vinyl....
Medicine Products: