Navigation Links
Immune cells predict success of head and neck cancer treatment, U-M study finds
Date:4/26/2010

ANN ARBOR, Mich. Levels of a key type of immune cell are higher in head and neck cancer patients whose tumors are linked to the human papillomavirus, or HPV, according to researchers at the University of Michigan Comprehensive Cancer Center.

The finding suggests a way to predict which tumors are most likely to respond to chemotherapy and radiation and allow doctors to choose the best treatment option up front.

"In the past, we would give toxic chemotherapy to a patient, look at how the tumor responded and then decide whether the patient needed surgery or radiation. Now with patients who have HPV-positive cancers, this study suggests we can look in the microscope, measure the level of these immune cells and, based on that, select a treatment that is going to be potentially less toxic for the patient and most effective at curing the cancer," says study author Gregory T. Wolf, M.D., professor and chair emeritus of otolaryngology at the U-M Medical School.

Results of the study will be presented April 29 at the American Head and Neck Society annual meeting.

The researchers looked at 66 patients with oropharyngeal cancer, which includes cancers of the tonsils and the tongue base. They measured levels of several immune system cells in the blood and tracked HPV status.

The HPV-positive patients had higher levels of a subset of T-lymphocyte cells, a type of immune cell that is responsible for killing tumor cells. Patients who responded to an initial round of chemotherapy also had higher levels of these cells, while patients whose cancer recurred had lower levels.

"When we looked at how successful chemotherapy and radiation were, the levels of those killer T-lymphocyte cells predicted who was going to do well. That ability to predict response was even better than when we look at whether the tumors were HPV-positive or negative," says Wolf, director of the Head and Neck Cancer Specialized Program of Research
'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Skin Condition Vitiligo Tied to Immune System Dysfunction
2. Immune sensors suppress colitis-associated cancer
3. Tumors hide out from the immune system by mimicking lymph nodes
4. Tumors Use a Protein to Hide From Immune System
5. Optimism May Boost Immune System
6. Researchers discover fundamental step in immune-system development
7. Optimism boosts the immune system
8. Go with Your Gut and Boost your Immune System with America's Favorite Fruit
9. Study Details Machinery of Immune Protection Against Inflammatory Diseases Like Colitis
10. Targeting blood vessels, immune system may offer way to stop infection-caused inflammation
11. New approach to immune cell analysis seen as first step to better distinguish health and disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immune cells predict success of head and neck cancer treatment, U-M study finds
(Date:7/13/2014)... 2014 Celebrity fitness trainer and former ... promotional partnership with Aqua Health Labs for their flagship ... supplement . The collaboration was recently announced live on ... trainer , actor, model, and a two time World ... celebrities, he has prepared stars including Demi Moore, Hilary ...
(Date:7/13/2014)... According to the Living With KP ... comprehensive guide that features a series of tips and ... (keratosis pilaris). This guide consists of 14 chapters including:, ... ,     Chapter 2: What Cause KP? , ... KP? ,     Chapter 4: Keratosis Pilaris Treatment , ...
(Date:7/12/2014)... The Chicken Egg Production ... years, buoyed by stable demand for industry products as ... are a relatively affordable staple for most families across ... grows in line with the size of the population,” ... for new specialty egg products with enriched qualities, such ...
(Date:7/12/2014)... Dennis Thompson HealthDay Reporter ... no way to guarantee that a surgical technique used to ... won,t increase the risk of spreading cancer to other parts ... The advisory panel to the Food and Drug Administration also ... laparoscopic power morcellation -- should sign a written consent stating ...
(Date:7/12/2014)... The fastest-growing mobile technology is LTE (Long Term Evolution). ... continues to grow due to the rapid evolution of ... data traffic, which is a major driver for the ... Measurement equipment comply with industry standards, and services which ... Market is estimated to grown from $3.75 billion in ...
Breaking Medicine News(10 mins):Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 2Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 3Health News:Chicken Egg Production in Canada Industry Market Research Report Now Available from IBISWorld 2Health News:Chicken Egg Production in Canada Industry Market Research Report Now Available from IBISWorld 3Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 2Health News:FDA Advisers Weigh Risks of Procedure for Removal of Uterine Fibroids 3Health News:North America Communication Test and Measurement (CT&M) Market Worth $1.9 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:North America Communication Test and Measurement (CT&M) Market Worth $1.9 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:North America Communication Test and Measurement (CT&M) Market Worth $1.9 Billion by 2018 - New Report by MicroMarket Monitor 4Health News:North America Communication Test and Measurement (CT&M) Market Worth $1.9 Billion by 2018 - New Report by MicroMarket Monitor 5
... especially present in the central nervous system, including// that ... as yet. Altered prionic proteins, pathogens, infectants, i.e. prions, ... spongiform encephalopathy (BSE or mad cow disease). In order ... Thus, the importance of this investigation for the location ...
... researchers at Johns Hopkins University claims that the drug Viagra ... could also reduce the effect of hormonal stress on the ... can in fact alter heart function. It alters it particularly ... Dr. David Kass, a professor of medicine at Johns Hopkins. ...
... like Kamal Hassan, Chiranjeevi, Nagarjuna, Venkatesh, Vikram, Sarath Kumar//, ... the awareness on AIDS. ,The show called 'A ... and Bill Gates Foundation was an evening of 'infotainment' ... partnership with others. I am very proud of my acting ...
... Prospective Investigation into Cancer and Nutrition (EPIC) showed that the ... people eating more than two portions a day of red ... portion a week. The investigation was set up 10 years ... people. Eating red and processed meat increases the risk of ...
... that depression may not be the only factor-probing adolescents ... to watch out for other mental health problems to ... re-examined the occurrence and distribution of mental disorders in ... An analysis of the results of the study revealed ...
... hernias are one of the most common conditions treated ... annually. Although ventral hernia repair (VHR) is a common ... infection has been identified as a consistent risk factor ... which appears in the November issue of The ...
Cached Medicine News:Health News:The 'Mad Cow' Disease And Protein 2Health News:Viagra Halves Effect Of Hormonal Stress On Heart 2Health News:Multi targeted approach required for suicide prevention in adolescents 2Health News:Predictors Of Wound Infection In Ventral Hernia Repair 2
(Date:7/11/2014)... , July 11, 2014  Rock Creek Pharmaceuticals, ... company, today announced that the Food and Drug Administration ... provide comments on RCP,s Investigational New Drug ("IND") application ... trial in the US. Dr. Chris ... review and comments on our IND. When we receive ...
(Date:7/11/2014)... , July 11, 2014 Research and ... Hypodermic Needles Market 2014-2018" report to their offering. ... A hypodermic needle is a hollow needle commonly used ... or or to extract fluids from it. A hypodermic ... to inject substances that cannot be ingested. Hypodermic needles ...
(Date:7/11/2014)... July 11, 2014 On ... down 0.52%, the Dow Jones Industrial Average finished the day ... 1,964.68, down 0.41%. The losses were broad based as eight ... S&P 500 Health Care Sector Index ended the day at ... the last one month. Investor-Edge has initiated coverage on the ...
Breaking Medicine Technology:Rock Creek Pharmaceuticals Issues Update On US Investigational New Drug Application 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4
... Iris Diagnostics iQ®200 Automated Urine Microscopy ... Auto-Particle Recognition (APR®) software to classify ... quantitatively report results. The iQ200 eliminates ... and interpret particle images by automating ...
... a very easy to use Ambulatory Urodynamic ... co-operation with practising urologists as an invaluable ... tract dysfunctions. The system offers the possibility ... during a natural bladder filling, extented over ...
... designed as a compact, cost-effective and easy-to-use ... clinics or as a second system. It ... commonly required investigations such as Uroflowmetry, Cystometry, ... options are available for Urethral Pressure Profilometry ...
... is a brand-new high technology state-of-the-art system ... flexibility and ease-of-use for every user. The ... for basic investigations as well as research ... set-up. This allows you to obtain the ...
Medicine Products: