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Immune cells need a second opinion
Date:2/4/2014

nary tract infections, were often observed to be a side effect. The findings now available explain the cause: If this messenger is blocked, the macrophages can no longer communicate with each other, and for this reason, the neutrophils are no longer sent to the site of the infection.

Basis for the development of new treatment strategies

This mechanism was decoded within the framework of doctoral theses by Marzena Schiwon and Christina Weisheit from the University of Bonn Medical center. "It is fundamental for our understanding of the antibacterial immune response," says Prof. Kurts. The signaling pathway may also play an important role in infections of other organs. This discovery may represent the basis for the development of new treatment strategies against bacterial infections in general.


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Contact: Dr. Daniel Engel
daniel.engel@uni-bonn.de
49-228-287-11050
University of Bonn
Source:Eurekalert  

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