Navigation Links
Immune System Marker Tied to Improved Bone Marrow Transplant Outcomes
Date:9/16/2013

Memphis, TN (PRWEB) September 16, 2013

The risk of death following bone marrow transplantation can be reduced about 60 percent using a new technique to identify bone marrow donors who make the most potent cancer-fighting immune cells, according to research from St. Jude Children’s Research Hospital. The findings appear in the September 16 online issue of the Journal of Clinical Oncology.

The research builds on an earlier St. Jude discovery that specialized immune cells called natural killer (NK) cells dispatched cancer cells more efficiently when the NK cells carried a particular version of a KIR protein on their surface. KIR is short for killer-cell immunoglobulin-like receptor. KIR proteins regulate NK cells.

For this study, researchers reviewed the outcomes of the 313 bone marrow transplants performed at St. Jude during the decade ending in January 2010. Investigators found that patients were far more likely to have survived the transplant and far less likely to have their disease progress if their new bone marrow came from donors whose NK cells included the same version of the protein, rather than the alternative form.

“This approach should dramatically improve the outcome for patients undergoing bone marrow transplantation, regardless of their age or underlying condition,” said Wing Leung, M.D., Ph.D., the paper’s corresponding author and chair of the St. Jude Department of Bone Marrow Transplantation and Cellular Therapy. “NK cells also play an important role in autoimmune disorders, chronic infections and other conditions, so these results will likely have an impact beyond cancer.”

Transplant patients benefited regardless of their disease, previous treatment, completeness of the genetic match or other donor characteristics, including whether the donor was a relative, Leung said. Screening for the NK cell variation uses blood collected for the current donor screening process and will not slow
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. The American Academy of Anti-Aging Medicine (A4M) Concluded the Gut, Brain and Autoimmune Disorders: the Role of Food Symposium August 17 in Los Angeles, CA
2. Study Finds GanedenBC30 Probiotic Supports Digestive and Immune Health in Healthy Seniors
3. Mood is influenced by immune cells called to the brain in response to stress
4. Bypassing Immune Rejection in Stem-Cell-Based Therapies
5. Nanodrug targeting breast cancer cells from the inside adds weapon: Immune system attack
6. Ohio State researchers restore immune function in spinal injured mice
7. Immune system molecule promotes tumor resistance to anti-angiogenic therapy
8. The American Academy of Anti-Aging Medicine (A4M) to host Gut, Brain, and Autoimmune Disorders: the Role of Food Symposium in Los Angeles, CA August 16-17, 2013
9. Premature aging of immune cells in joints of kids with chronic arthritis, Pitt team says
10. Isolated psychiatric episodes rare, but possible, in common form of autoimmune encephalitis
11. Mount Sinai researchers discover mechanism behind development of autoimmune hepatitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... December 26, 2014 It is said that ... dress. Today, UWDress.com, the famous wedding dress supplier, shows ... a site-wide cocktail gown promotion. , UWDress.com’s navy cocktail ... and they come in high fashion styles. Simple dresses in ... on the occasion; they are specially designed for those who ...
(Date:12/26/2014)... 2014 Yisrayl Hawkins, Pastor at The House ... in light of the Ferguson, Missouri unrest. Yisrayl starts his ... and explains why it has only increased. , He ... created. He says there is a very specific reason for ... there is a set of rules, or Laws that if ...
(Date:12/26/2014)... 26, 2014 Plugin and template developers from ... 5 Plugin for Final Cut Pro X. , “TransPack Volume ... tool to pull off an industry professional look” Said Christina ... hands on TransPack Volume 5, a new level of professionalism ... set of over 50 Final Cut Pro X transitions featuring ...
(Date:12/26/2014)... India Network Foundation, a non-profit US based ... today a new version of “ EasySelect ”, a ... plan for their visiting parents. The technology tool is ... process when choosing an insurance plan by showing the ... few clicks. Many elderly Asian Indian parents often find ...
(Date:12/26/2014)... (DaWei Induction Heating Co.) is a comprehensive high-tech business ... of a series of induction heating equipment. Today, the ... induction brazing equipments . , According to a ... refers to the joining of two or more components ... says that there are fundamental differences in the two ...
Breaking Medicine News(10 mins):Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2Health News:Yisrayl Hawkins Pleads for Peace in Ferguson and Beyond in New Open Letter 2Health News:Today a new plugin was announced from Pixel Film Studios, TransPack Volume 5 for Final Cut Pro X 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2
... HealthDay Reporter , THURSDAY, April 14 (HealthDay News) ... cancer survivors after successful treatment stems from a tug ... the autonomic nervous system, with the former working overtime ... new study suggests. Researchers from Ohio State University ...
... Calif., April 14, 2011 New survey data released ... 20th Annual Meeting and Clinical Congress reveal that more ... across the country report they have experienced hypoglycemia, or ... typical daily activities such as working (42%), exercising (26%) ...
... Institute today announced a collaboration and strategic agreement ... rapid development of a vaccine and accelerate preparedness ... as pandemic influenza. The team, composed of Duke ... National Institute of Allergy and Infectious Diseases-sponsored Regional ...
... by researchers at the University of Alberta shows that for ... as well as prolonged exercise is the key to the ... of Rehabilitation Medicine, and Alex Clark, researcher in the Faculty ... Schopflocher in the School of Public Health, and Ian Paterson ...
... , THURSDAY, April 14 (HealthDay News) -- Parents who ... setting a bad example; they,re actually helping the children learn ... children ages 18 to 30 months found that older children ... when a voice explaining the item stumbled and said, "Look ...
... INDIANAPOLIS With mounting evidence that patient-centered care ... and Indiana University School of Medicine are providing ... future physicians to master relationship skills as well ... 21st Century medicine. "Crossing the ...
Cached Medicine News:Health News:Nervous System Imbalance May Cause Fatigue in Breast Cancer Survivors 2Health News:Nervous System Imbalance May Cause Fatigue in Breast Cancer Survivors 3Health News:New ACE survey shows people with type 2 diabetes experience low blood sugar during typical daily activities 2Health News:New ACE survey shows people with type 2 diabetes experience low blood sugar during typical daily activities 3Health News:Duke Human Vaccine Institute signs research agreement to develop pandemic virus vaccines 2Health News:Duke Human Vaccine Institute signs research agreement to develop pandemic virus vaccines 3Health News:Heart needs work after heart attack: U of A Study challenges the notion that the heart must rest 2Health News:Training future doctors to enlist patients as partners in care 2
(Date:12/24/2014)... , Dec. 23, 2014  Advanced Medical Isotope ... engaged primarily in the development of brachytherapy devices ... today announced that it has filed a ... Drug Administration ("FDA") for marketing clearance for its ... of the U.S. Food, Drug and Cosmetic Act ...
(Date:12/24/2014)... 23, 2014   Synageva BioPharma Corp. ... developing therapeutic products for rare disorders, today announced ... the Marketing Authorization Application (MAA) for sebelipase alfa ... company,s request for accelerated assessment, which has the ... The MAA, and the Biologics ...
(Date:12/24/2014)...  The American Diabetes Association is recommending a ... with diabetes and that all people with diabetes ... in keeping with recent changes to guidelines for ... of Cardiology (ACC) and American Heart Association (AHA). ... changes to the Association,s annual revised Standards of ...
Breaking Medicine Technology:Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4
... HOUSTON, Aug. 24, 2011 eCardio Diagnostics ( www.ecardio.com ... annual Inc. 500|5000, an exclusive ranking of the nation,s ... consecutive year, ranking #912 overall and #65 in the ... of 335%. The list represents the most ...
... Corporation (NYSE: CVS ) today announced that ... repurchase program for up to $4.0 billion of the ... is effective immediately, permits the company to effect the ... open market repurchases, privately negotiated transactions, accelerated share repurchase ...
Cached Medicine Technology:Inc. Magazine Unveils Its Annual Exclusive List of America's Fastest-Growing Private Companies—the Inc. 500|5000 2CVS Caremark Corporation Announces New Share Repurchase Authorization for up to $4 Billion of Common Stock 2CVS Caremark Corporation Announces New Share Repurchase Authorization for up to $4 Billion of Common Stock 3
... with concave seats and large backrests ... like seats, backrests, armrests, and casters ... Series for top performance in a ... laboratory, clean room, static control, health ...
... ergonomic chairs with concave seats and ... Select options like seats, backrests, armrests, ... the BE Series for top performance ... industry, education, laboratory, clean room, static ...
... chairs with concave seats and large ... options like seats, backrests, armrests, and ... BE Series for top performance in ... education, laboratory, clean room, static control, ...
... Durable ergonomic chairs with concave seats and ... options like seats, backrests, armrests, and casters ... for top performance in a variety of ... static control, health care and office. • ...
Medicine Products: