Navigation Links
Immune System Gene Discovery Sheds Light on Staph Infections
Date:7/21/2009

Findings could lead to better therapies for severe forms of the disease

TUESDAY, July 21 (HealthDay News) -- Researchers at the University of Texas Southwestern Medical Center have figured what genes turn on and off in a person's immune system when he or she has a severe staph infection.

The work, done on children with severe Staphylococcus aureus infections but applicable to all people, could lead to better treatments for these diseases, including the methicillin-resistant (MRSA) version known as the "super bug" because most antibiotics do not work on it.

According to the findings, published in the online journal PLoS One, the genes in children's innate immune system, which provides the most immediate response to infection, became overactive when S. aureus hits. Meanwhile, the genes in the children's adaptive immune systems, which recall past battles to better fight later infections, are shut down.

"It's a very sophisticated and complex dysregulation of the immune system, but our findings prove that there's consistency in the immune response to the staphylococcus bacterium," lead author Monica Ardura, an instructor of pediatrics at UT Southwestern, said in a school news release. "Now that researchers know how the immune system responds, the question is whether this methodology can be used to predict patient outcomes or differentiate the sickest patients from the less sick ones and, ultimately, how this knowledge can be used to develop better therapies?"

She emphasized, though, that the findings were only a snapshot of what occurs during a staph infection at a single moment.

The researchers conducted gene expression profiling with blood taken from 53 otherwise healthy children who had contracted one of the strains of S. aureus during a five-year period and 24 healthy control patients.

The team plans to try to study other conditions surrounding the period bef
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Cell division find prompts overhaul of immune response modeling
2. Intravenous Immune Biologics Will Suffer from the Pending Shift in Coverage from the Medical to the Pharmacy Benefit
3. Researchers map how staph infections alter immune system
4. Immune Response May Speed AIDS Progression in Women
5. UCLA scientists identify how immune cells may help predict Alzheimers risk
6. Strep B Seems to Trick Immune System
7. Post-transplant combo can replace toxic immune-suppressing drugs in monkeys
8. Catalyst Biosciences Announces Agreement With MedImmune to Discover and Develop Engineered Protease Therapeutics
9. CU-Boulder study shows brains immune system may cause chronic seizures
10. Autism May Be Linked to Moms Autoimmune Disease
11. Microscopic beads could help create designer immune cells that ignore transplanted organs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immune System Gene Discovery Sheds Light on Staph Infections
(Date:7/13/2014)... 2014 Recently, 2014QuinceaneraDresses.com, the distinguished ... its new range of gorgeous Quinceanera dresses ... demand for elegant Quinceanera outfits is huge. Therefore, ... All the company’s newly released dresses are made ... all elegant and vivid. , It is ...
(Date:7/13/2014)... 2014 Epidemiologists forecast an increase in ... from 8,062 diagnosed incident cases in 2013 to 11,568 ... Rate (AGR) of 4.35%, during the forecast period. In ... diagnosed incident cases of aGVHD in the 6MM, with ... lowest number of diagnosed incident cases of aGVHD, with ...
(Date:7/13/2014)... July 13, 2014 Wright & Schulte ... has been scheduled in July of 2015, in U.S. ... lawsuits are in the discovery process in the ... Gergel is presiding over the multidistrict litigation (MDL). The ... behalf of individuals who allege that they took the ...
(Date:7/13/2014)... Palatine, Illinois (PRWEB) July 13, 2014 Hope ... facilitating a monthly grief support group at the Tamarack Senior ... will be held at 10:30 A.M. on the 3rd Wednesdays ... July 16th, 2014 at the Tamarack Community located at 55 ... to all bereaved individuals and there is no cost for ...
(Date:7/13/2014)... Recently, iFitDress.com, one of the most popular suppliers ... added a new selection of beautiful evening dresses ... a promotion for these evening gowns. Now, everybody can ... providing thousands of graceful gowns in its online store. ... France, Italy and many other countries. They are highly ...
Breaking Medicine News(10 mins):Health News:2014QuinceaneraDresses.com Releases Its New Quinceanera Dresses 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 2Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 4Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2Health News:New and Beautiful Evening Dresses Unveiled by iFitDress.com 2
... have only recently begun to speculate that whats referred to ... genome that doesnt encode for proteins and previously seemed to ... for an important reason. ,But it wasnt ... of California, San Diego (UCSD) School of Medicine have discovered ...
... counters concerns of health care providers reluctant to invest in ... be published in the July issue of the Journal of ... medical center recouped its investment in electronic health records within ... medical records in New Orleans after Hurricane Katrina is one ...
... not to board a transatlantic flight with a potentially deadly ... and two Czechs who flew with him, media said ... scare two months ago when he flew to Montreal via ... Disease Control (CDC) had said he was infected with a ...
... Medicine have found that a newly available monoclonal antibody ... cells. ,In a study, the monoclonal ... and survival in human and mouse hepotocellular cancer (HCC) ... the new findings have significant implications not only for ...
... study conducted by University of Alberta and McGill University indicate ... depression. The rate of women is much higher compared ... recently in the European Journal of Cardiovascular Nursing. ,486 ... per cent of the women had worsening depression one year ...
... air pollution stats provided by the Ontario health department is ... deaths and 6,000 hospital admissions in Toronto each year, Dr. ... of the air quality health index. , The politicians ... a new plan to control air pollution. A new tool ...
Cached Medicine News:Health News:The Importance of Junk DNA 2Health News:Electronic Medical Records can Pay You Within 16 Months 2Health News:US TB Traveler Sued Over 'reckless and Selfish Behavior' 2Health News:Monoclonal Antibody Induces Death in Liver Cancer Cells 2Health News:Female Heart Attack Victims Show Signs of Lasting Depression 2
(Date:7/10/2014)... MUMBAI, India , July 11, 2014 /PRNewswire/ ... the treatment of cancer are being highlighted in ... Mumbai from 10-12 July, 2014.  Renowned ... meeting to share best practices and exchange knowledge ... more precise, accurate and efficient. ...
(Date:7/10/2014)... , July 10, 2014  The U.S. Department ... three-year grant to University Hospitals (UH) Case Medical Center ... new national model aimed at improving care for patients ... Care," the project will test a unique model developed ... with late-stage disease, significant comorbidities, or demonstrated need for ...
(Date:7/10/2014)... 10, 2014 Integrated Silicon Solution, Inc. (Nasdaq: ... and analog IC solutions, today announced that it will ... 2014, at 7:00 a.m. Pacific Time (10:00 a.m. Eastern ... fiscal 2014 third quarter ended June 30, 2014. ... 1-888-556-4997 before 6:50 a.m. Pacific time on July 24, ...
Breaking Medicine Technology:Improving quality and access to advanced cancer care in India and South Asia 2Improving quality and access to advanced cancer care in India and South Asia 3Improving quality and access to advanced cancer care in India and South Asia 4Improving quality and access to advanced cancer care in India and South Asia 5University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4
The Benchmark Microplate Reader, with its increased wavelength range of 340 to 750 nm and high performance optics, provides flexibility for specialized applications requiring increased linearity, ult...
Elisa strip reader...
Iems Incubator/Shaker expansion module for 2 module incubator/shaker. high performance microplate incubator and orbital shaker. It's superior temperature control and efficient orbital shaking reduce ...
... Millennium 2000 is a unique microprocessor controlled ... microplates in either 96 or 384 well ... via the control panel and all are ... visible under the clear protective cover. The ...
Medicine Products: