Navigation Links
Imaging shows long-term impact of blast-induced brain injuries in veterans
Date:12/1/2013

CHICAGO Using a special type of magnetic resonance imaging (MRI), researchers have found that soldiers who suffered mild traumatic brain injury (MTBI) induced by blast exposure exhibit long-term brain differences, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

Recent wars have resulted in veterans with an exposure rate of approximately 20 percent to blast-induced MTBI, or trauma resulting from mortar fire and improvised explosive devices. Diagnosis can be challenging, especially in mild cases.

"Mild traumatic brain injury is difficult to identify using standard CT or MRI," said study co-author P. Tyler Roskos, Ph.D., a neuropsychologist and assistant research professor at the Saint Louis University School of Medicine in St. Louis, Mo. "Other methods may have added sensitivity."

One of those methods is diffusion tensor imaging (DTI), an MRI technique used to identify microstructural injury to white matter, the part of the brain that consists mostly of signal-carrying axons. Damage-associated changes in water movement along the axons are comparable in certain respects to what might happen with a garden hose, according to co-author Thomas M. Malone, B.A., research associate at Saint Louis University School of Medicine.

"As water passes through the hose from the faucet to the sprinkler, it goes in the same direction, but if you were to puncture the hose with a rake, the water would shoot out the sides," Malone said.

In the study, researchers compared DTI-derived fractional anisotropy (FA) values in 10 veterans of Operations Iraqi Freedom and Enduring Freedom who had been diagnosed with MTBI with those of 10 healthy controls. FA measures the uniformity of water diffusion throughout the brain, and low FA tends to indicate areas of axonal injury. The average time elapsed between the blast-induced injury and DTI among the patients was 51.3 months.

"The time since injury is a novel component to our study," Dr. Roskos said. "Most other blast-related MTBI studies examine patients in the acute phase of injury."

Comparison of FA values showed significant differences between the two groups, and there were significant correlations between FA values and attention, delayed memory and psychomotor test scores. Since the victims were, on average, more than four years removed from their injuries, the results suggest the presence of a long-term impact of blast injury on the brain.

"This long-term impact on the brain may account for ongoing cognitive and behavioral symptoms in some veterans with a history of blast-related MTBI," Dr. Roskos said.

The results also indicate that DTI is sensitive to group differences in blast-related MTBI even in the post-acute phase.

"DTI shows promise in enhanced sensitivity for detecting MTBI compared to MRI/CT, even in the chronic phase," Dr. Roskos said. "Identification of changes in specific brain regions may help in diagnosis and treatment of MTBI among veterans."

Dr. Roskos explained that this research is aimed at finding better ways for the clinician to differentiate between MTBI and PTSD in veterans in order to improve treatment.

"It makes a difference, because PTSD is psychological in nature and MTBI is neurological," he said. "Many veterans in the healthcare system are dealing with MTBI, PTSD or both. Our emphasis today is to find the best treatments and measure the patient's progress. Imaging has the potential to do that."


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Special journal issue focuses on imaging screening
2. BCC Research Publishes A New Report On Global Markets For Molecular Imaging Devices
3. Study Funded by National Foundation for Cancer Research Reveals Imaging Studies May Predict Tumor Response to Anti-Angiogenic Drugs
4. Advanced CT imaging proves as accurate as invasive tests to assess heart blockages, study shows
5. Brain imaging reveals dynamic changes caused by pain medicines
6. Global Medical Imaging Equipment Market Is Expected to Reach USD 35.35 Billion in 2019: Transparency Market Research
7. Enterprise Imaging Speeds Ahead with Visage 7
8. Worlds largest imaging congress reveals latest techniques in heart failure
9. Some Imaging Tests Not Worth the Costs and Risks, From the November 2013 Harvard Women's Health Watch
10. Cone Beam Imaging Technology is Now Used by Dr. Robert Mokbel for Precise Placement of Dental Implants in Fountain Valley, CA
11. Breast cancer -- combining imaging techniques for quicker and gentler biopsies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... , ... May 23, 2016 , ... ... Texas Veterinary Medical Association (TVMA) reminds pet owners that intervening at the first ... Heatstroke occurs when a pet’s normal body mechanisms cannot keep the body’s temperature ...
(Date:5/23/2016)... ... May 23, 2016 , ... California ... on discriminated minorities’ quality of life and is currently focusing on ways to ... documentaries to be tested through research to find out whether watching them could ...
(Date:5/23/2016)... ... May 23, 2016 , ... During ... Missouri, campus, Standard Process Inc. awarded $6,000 in chiropractic scholarships. The ... Tillman. Each student is in her fifth trimester of classes at Logan. , ...
(Date:5/23/2016)... ... May 23, 2016 , ... Hospice of ... Westchester County for over 24 years, recently hosted its sixth annual Celebration of ... for two remembrance ceremonies, each concluding with the release of Monarch butterflies that ...
(Date:5/23/2016)... (PRWEB) , ... May 23, 2016 , ... ... company’s top management team to meet the needs of its recent and anticipated ... drive continued growth and business development across widening market segments. Max joined the ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... 23, 2016 Transparency Market Research ... Pancreatic Insufficiency Market - Global Industry Analysis, Size, Share, ... to the report, the exocrine pancreatic insufficiency market is ... 2015 to 2023 to reach US$2.85 Bn by 2023. ... characterized by the deficiency of the exocrine pancreatic enzymes, ...
(Date:5/23/2016)... May 23, 2016 Experts from ... Precision Medicine and the role of technology in ... The First International Conference of VPS-Penn Medicine opened ... patronage and presence of Sheikh Nahyan bin Mubarak Al Nahyan, ... Precision Medicine, which helps provide personalized medicine and tailor-made healthcare ...
(Date:5/20/2016)... , May 20, 2016 ... 2016 to Medical Devices of its online business ... survey on the current state of the Titrator ... the industry like definitions, classifications, Specifications, applications and ... manufacturing process like Raw Material Suppliers, Equipment Suppliers, ...
Breaking Medicine Technology: