Navigation Links
Imaging fat layer around heart can help predict disease
Date:3/15/2010

Imaging epicardial adipose tissue, or the layer of fat around the heart, can provide extra information compared with standard diagnostic techniques such as coronary artery calcium scoring, according to research by cardiologists at Emory University School of Medicine. The size of the layer of fat around the heart can be measured by X-ray imaging techniques such as CT or MRI.

"This information may be used as a 'gate keeper', in that it could help a cardiologist decide whether a patient should go on to have a nuclear stress test," says Paolo Raggi, MD, professor of medicine (cardiology) and radiology and director of Emory's cardiac imaging center.

Results from two studies were presented at the American College of Cardiology meeting in Atlanta on Sunday, March 14.

The first study, presented by cardiology fellow Nikolaos Alexopoulos, MD, now at the University of Athens, Greece, shows that patients with a larger volume of epicardial adipose tissue tend to have the types of atherosclerotic plaques cardiologists deem most dangerous: non-calcified plaques.

Calcium tends to build up in atherosclerotic plaques. Even though the heart's overall coronary calcium burden is a good predictor of heart disease, calcium in an individual plaque doesn't necessarily mean imminent trouble, Raggi says. Researchers have been learning that non-calcified plaques indicate active buildup in that coronary artery, and studies suggest that the fat around the heart secretes more inflammatory hormones, compared to the fat just under the skin.

"Release of inflammatory factors from epicardial adipose tissue may be promoting an active atherosclerotic process, and this is indicated by the presence of non-calcified plaques," Raggi says.

Emory researchers examined 214 patients through cardiac CT, and performed coronary artery scoring as well as assessing the patients' epicardial adipose tissue volume and the plaque in their coronary arteries. The epicardial adipose tissue volume was highest in the patients with non-calcified plaques (roughly 60 percent more than those with calcified plaques).

The second study, presented by Emory cardiology fellow Matthew Janik, MD, measured epicardial fat in patients receiving a nuclear stress test. The 382 patients had chest pain but did not have known cardiovascular disease. A nuclear stress test picks up signs of inducible ischemia: deficiencies in blood flow in the heart muscle.

Here, the researchers found that the presence of ischemia correlated more closely with epicardial adipose tissue volume than with the coronary calcium score.


'/>"/>

Contact: Jennifer Johnson
jrjohn9@emory.edu
404-227-3683
Emory University
Source:Eurekalert

Related medicine news :

1. Promega - TOP srl Agreement Enables Live Animal Imaging for Cancer Studies
2. Artists, Product Designers, Printing Gurus, Game Developers, Manufacturing Engineers Will Converge at RAPID 2010/3D IMAGING Conference/Expo, May 18-20 in LA
3. National Council on Aging Releases Survey on Medical Imaging Safety
4. Imaging manufacturers: Plan to reduce unnecessary radiation exposure and medical errors
5. Less is more in cancer imaging
6. Medical Imaging Northwest Completes Phase I of Its Healthcare IT Integration to Maintain Patient Care Improvements
7. SNMs Conjoint Mid-Winter Meetings continue to advance molecular imaging
8. Neuroimaging study may pave way for effective Alzheimers treatments
9. New Study Demonstrates Novel Use of Metabolic Imaging to Locate Sperm in Infertile Men -- Non-Invasive Imaging Procedure May Replace Invasive Techniques such as Testicula
10. New paper describes important advance in imaging of cell death
11. Promising new neuroimaging techniques for early detection of Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... December 07, 2016 , ... ODU, a ... the US market its advanced highly customizable contact technology solutions. , ODU Single ... advanced technologies are ideal for a wide range of applications that require customization ...
(Date:12/7/2016)... ... , ... One of two inventors from Glen Burnie, Md., has a granddaughter ... "This is why the co-inventor and I have designed a new and better way ... prototype of the patent-pending AV-AIR, a device that serves as an alternative to conventional ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... Sharon Kleyne, ... Global Climate Change and Your Health on Voice of America, declared on her radio ... call attention to the fact that when these bullies attack leaders in corporate America, ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... is condemning "scam operations" carried out by unethical locksmith companies and is urging ... to a halt. According to Texas Premier Locksmith, these fraudulent locksmith services take ...
(Date:12/7/2016)... ... 2016 , ... Gensuite is honored to be selected as ... Product Launch category. Gensuite’s entry on their EZ Scan feature detailed the tool’s ... Training Group is a professional event and training provider based in the United ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... Boehringer Ingelheim today announced that the ... malignant pleural mesothelioma (MPM) met its primary endpoint ... the 17 th IASLC World Conference on ... showed nintedanib plus pemetrexed/cisplatin demonstrated a meaningful clinical ... significantly improved PFS (9.4 vs 5.7 months). Preliminary ...
(Date:12/7/2016)... 7, 2016 According to the ... Global Market Study on Multiplex Detection Immunoassay: North America ... the global multiplex detection immunoassay market is expected to witness a ... ...      (Logo: http://photos.prnewswire.com/prnh/20161114/438683LOGO) ...
(Date:12/6/2016)... , Dec. 6, 2016  "Blood Tests replace ... announced ....." The Diagnostic, Monitoring and Screening ... cancer diagnostics is occurring using in vitro blood ... company with impressive backing, has announced a single ... is moving faster than the market. New technology ...
Breaking Medicine Technology: