Navigation Links
ImQuest Presentations at Keystone Symposium Focus on Advancements in Their Therapeutic and Microbicide Development Programs
Date:3/25/2009

FREDERICK, Md., March 25 /PRNewswire/ -- ImQuest Life Sciences presented their latest biological results supporting the continued development of their small molecule pyrimidinedione inhibitors of HIV-1 at the Prevention of meeting being held in Keystone, Colorado. The presentations highlighted new data supporting the selection of lead second generation therapeutic agents with an increased barrier to the selection of drug resistant virus strains in treated patients, as well as preclinical studies supporting the development of the pyrimidinedione IQP-0528 as a topical microbicide candidate for human clinical trials. The pyrimidinediones are highly potent inhibitors of HIV, exhibiting a dual mechanism of action which includes targeting virus entry and reverse transcription, a highly positive safety profile, and enhanced sensitivity against multi-drug resistant viruses isolated from patients. ImQuest recently submitted an Investigational New Drug Application to the FDA to initiate Phase 1 human clinical trials with the pyrimidinedione IQP-0410.

Robert W. Buckheit, Jr., Ph.D. (Executive Vice President and Chief Scientific Officer) presented the results of studies which demonstrate the ability of various analogs of IQP-0410 to more effectively suppress the replication of viruses which are resistant to the action of other NNRTIs used in the clinic. ImQuest, in collaboration with their drug development partner Samjin Pharmaceutical Co. Ltd of Seoul, Korea, have recently engaged in an effort to develop more active pyrimidinediones possessing this higher genetic barrier to resistance. Karen M. Watson, M.S. (Director, Topical Microbicide Research & Development) reported on results of preclinical efficacy evaluations of a series of pyrimidinediones, resulting in the selection of IQP-0528 as ImQuest's lead compound to prevent the sexual transmission of HIV worldwide. The studies included ImQuest co-authors Tracy Hartman, M.S., Lu Yang, M.D. and Chr
'/>"/>

SOURCE ImQuest Life Sciences
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528
2. SimQuest Awarded Phase 2 Contract from Office of the Secretary of Defense to Develop Pandemic Influenza Training Program
3. Accuray to Webcast Senior Management Presentations at Analyst Day Event
4. SuperGen to Highlight Oncology Pipeline Data in Multiple Presentations at the AACR-NCI-EORTC International Conference
5. Forest Laboratories and Cypress Bioscience to Host Webcast to Discuss Clinical Data Presentations for Milnacipran
6. Cell Therapeutics, Inc. (CTI) CIBC and Rodman & Renshaw Healthcare Conference Presentations to be Webcast
7. Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) to be Presented at the Upcoming American Society of Hematology Meeting in Atlanta, Georgia
8. Inexpensive Online Pain Education Program for Physicians as Effective as Live Presentations by National Experts
9. Derma Sciences Announces Several Clinical Presentations on MEDIHONEY(TM) Wound & Burn Dressings at Upcoming APWCA Conference
10. Uroplasty, Inc. Reports Presentations of Urgent(R) PC Studies at the 2008 Society of Urologic Nurses and Associates Annual Symposium
11. Trubion Announces Presentations at Upcoming Investor Conferences
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... AcousticSheep LLC participated in one of ... the first Color Run – otherwise known as the “Happiest 5K ... and over 10,900 participants from Erie, surrounding areas, and even from ... one of the largest running events put on in Erie, PA ... “Happiest 5K on the Planet.” The event took place on August ...
(Date:8/22/2014)... 2014 For the fourth time, TharpeRobbins, ... recognition industry, has received a prestigious level of recognition ... of 134%, TharpeRobbins remains on the exclusive list of ... was previously on the list in 2010, 2011 and ... in this distinguished list for a fourth time," says ...
(Date:8/22/2014)... 22, 2014 Minorities in Orange and Los ... comes to mental health and recovery from trauma. Casa de ... the gap between local minorities and the help they need. ... by making the connection between mental and physical health. , ... at their fitness boot camp, located at 16560 Harbor Blvd., ...
(Date:8/22/2014)... August 22, 2014 Medical Solutions, the ... earned a position on the Inc. 5000 list, amongst ... placed in position 1424 on the list, with 300% ... million. This marks the seventh time in the last ... on the Inc. 5000, including one year on the ...
(Date:8/22/2014)... Dallas, Texas (PRWEB) August 22, 2014 ... from $297 million in 2013 to $407 million by ... 6.59%. The company’s latest report “OpportunityAnalyzer Graft-Versus-Host Disease – ... growth, which will occur over six major markets (6MM: ... will be strongest in the five European countries (5EU), ...
Breaking Medicine News(10 mins):Health News:RunPhones® Reveals Erie, PA Enthusiasm Impressed Color Run Director 2Health News:RunPhones® Reveals Erie, PA Enthusiasm Impressed Color Run Director 3Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 2Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 3Health News:Fountain Valley Fit Body Boot Camp Announces Fitness Boot Camp Fundraising Event for Casa de Familia 2Health News:Fountain Valley Fit Body Boot Camp Announces Fitness Boot Camp Fundraising Event for Casa de Familia 3Health News:Medical Solutions Earns Position on the 2014 Inc. 5000 List 2Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 2Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 3Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 4
... Informatics Corporation of America (ICA), formed three ... physicians and informatics professionals at Vanderbilt Medical ... today that the MidSouth eHealth Alliance (MSeHA) ... ICA’s commercial version of the solution to ...
... The Agency for,Healthcare Research and Quality has ... reduce central line-associated bloodstream infections in,hospital intensive care ... previous AHRQ-funded project. The Health Research & Educational ... been selected to,coordinate the new 3-year project, which ...
... Responding to the growing need,for allied healthcare ... new,program that presents qualified allied travel candidates to ... Careers,provides the company with an extension to its ... recruit travel medical,professionals now have the opportunity to ...
... Modeled After Highly Successful MHA Keystone: ICU Patient ... The Agency for Healthcare,Research and Quality (AHRQ) today ... patients, risk of hospital-associated infections,in intensive care units ... the pioneering efforts,of the Michigan Health & Hospital ...
... Per the Maryland Stem Cell,Commission (Commission) meeting on ... Requests for Applications (RFAs) for funding,through the Maryland Stem ... This is the third round of funding from the ... of $19 million for FY,2009. However, it should be ...
... Medical,Inc. (Nasdaq: BFRM ) announced today that it ... Conference on Tuesday, October 7, 2008. Derek,Bertocci, Chief Financial ... overview of the Company at 2:30 p.m. (ET) in ... will be webcast live and can be,accessed at through ...
Cached Medicine News:Health News: MidSouth eHealth Alliance to Transition to Commercial Software Solution from Informatics Corporation of America 2Health News: MidSouth eHealth Alliance to Transition to Commercial Software Solution from Informatics Corporation of America 3Health News:AHRQ Awards $3 Million to Help Reduce Central Line-Associated Bloodstream Infections in Hospital ICUs 2Health News:Travel Nurse Source Expands Lead Service to Allied Healthcare Travel Sector with Introduction of AlliedTravelCareers.com 2Health News:Michigan Success Lands National Research Contract to Reduce Hospital-Associated Infections in 10 States 2Health News:Maryland Stem Cell Commission Issues Requests for Applications 2Health News:Maryland Stem Cell Commission Issues Requests for Applications 3Health News:BioForm Medical to Present at the 2008 Maxim Group Growth Conference 2
(Date:8/21/2014)... , Aug. 21, 2014  Seventy-one percent of Americans ... OxyContin is a serious public health and safety issue in ... from a survey released today by Repass & Partners, a ... "Americans understand the severity of the prescription medication ... progress with this very serious health situation facing our country," ...
(Date:8/21/2014)... 2014 InfinityQS International, Inc., the global ... , today announces Infusion Chicago, its 9 th ... held Oct. 9-10, 2014, at the Chicago Marriott ... the necessity for implementing a quality system that ... to gain insight into production processes. Complimentary registrations ...
(Date:8/21/2014)... 21, 2014 Professional Compounding Centers of ... by awarding the three best scientific presentations at ... conference . The Formulating Better Medicines for ... Athens, Greece , includes dozens ... professionals, from which three winners will be selected ...
Breaking Medicine Technology:Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3InfinityQS to Host Manufacturing Intelligence Conference in Chicago 2Professional Compounding Centers of America will award top poster-session winners at European Paediatric Formulation Initiative in Athens 2
... Conatus Pharmaceuticals Inc., a privately held, clinical stage ... Hepatitis C Virus (HCV), announced today that Steven J. ... at the Montgomery Healthcare Conference being held in Menlo ... of only 30 companies selected to present to this ...
... Hospital of Arcadia, California, has launched an integrated ... solutions designed to help improve the quality of ... health care information technology subsidiary of Quest Diagnostics ... solution to help Methodist reduce the length of ...
Cached Medicine Technology:Conatus Pharmaceuticals to Present at the Montgomery Healthcare Conference 2Methodist Hospital Adopts New Technology Solutions to Improve Care for California Patients and Reduce Operating Costs 2Methodist Hospital Adopts New Technology Solutions to Improve Care for California Patients and Reduce Operating Costs 3Methodist Hospital Adopts New Technology Solutions to Improve Care for California Patients and Reduce Operating Costs 4
Bivona® Uncuffed Neonatal and Pediatric Silicone Tracheostomy Tubes....
Bivona® Uncuffed Neonatal and Pediatric Silicone Tracheostomy Tubes....
Aire-Cuf® tracheostomy tubes are ideal for short-term to medium-term ventilator support....
... TTS™ tracheostomy tubes are available in both neonatal ... like an uncuffed tube, but it has a ... the shaft of the tube. , ,TTS™ ... tube with the insurance of a cuff, if ...
Medicine Products: