Navigation Links
Illuminating fractures: X-ray imaging sheds new light on bone damage
Date:3/7/2013

, called caniliculi, were not visible.

The imaging involved special preparation of sheep bone samples led by graduate student and first author Garry Brock. First they cut 2 mm square matchstick-like samples.

The matchsticks were "damaged" in the lab at various levels: Some received 20,000 cycles of "loading" in bending; others received a single dose of loading; and others were notched before loading. All samples were treated with a lead-uranyl acetate X-ray negative stain that seeps into porosity caused by damage in the bone tissue. Then sections from the loaded segment were polished to 50-micron thicknesses.

A greater amount of stain was seen in sections subjected to repetitive stress. But instead of seeing new surfaces formed by damage, or cracks, as was expected, the researchers observed damage in the cellular structures. The X-rays picked up the dye within existing, intact structures, like the lacunae where the cells sit, and in the caniliculi.

"The tissue is not breaking, but rather, there is staining within the cells," Brock said.

Added van der Meulen: "We were surprised by how cell-based the staining was, as opposed to forming lots of new surfaces in the material."

In osteoporotic individuals, including many postmenopausal women, fractures usually occur in the forearm, spine and hip. van der Meulen's team is trying to understand why these fractures occur by studying nano- and microscale changes in bone tissue.

They are also exploring the possibility of studying whether a class of osteoporosis drugs called bisphosphonates, which reduce the overall rate of hip fractures but can lead to "atypical femoral fractures," affect nanoscale damage processes. These unusual fractures occur at sites that normally do not fracture with osteoporosis such as in the middle of the bone shaft. The new damage visualization method could lend new insights in future studies.


'/>"/>
Contact: Syl Kacapyr
vpk6@cornell.edu
607-255-7701
Cornell University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dental X-Rays May Be Linked to Benign Brain Tumors
2. Screening for breast cancer without X-rays: Lasers and sound merge in promising diagnostic technique
3. Empa X-ray expert decodes diesel soot
4. X-Rays May Up Breast Cancer Risk for Women With Certain Genes: Study
5. Airport Security X-Rays May Damage Diabetes Devices
6. Arizona Dental Heights Moves to Using the New Nomad Pro Hand Held X-Ray System
7. A Media Representative for Dr. Castro Announces New Updates on the Dental Implants Specialist in Rancho Cucamonga's Website with Information on Digital X-Rays
8. Fighting sleeping sickness with X-ray lasers
9. Live imaging shows response to cancer drugs can be boosted by altering tumor microenvironment
10. MR enterography is as good or better than standard imaging exams for pediatric Crohns patients
11. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Pallarito HealthDay Reporter FRIDAY, ... without health insurance this year will face fines of up ... five, the Internal Revenue Service says. The Obama administration ... penalties that some Americans will owe for failing to have ... the monthly national average premium for a bronze-level health plan. ...
(Date:7/28/2014)... Pittsburgh, PA (PRWEB) July 28, 2014 ... lids kept shutting," said one of two inventors from ... hold the lids open so that we could pour ... for the CONKLIN'S STAY OPEN to keep the lids ... prevents lids from closing until all compartments have been ...
(Date:7/28/2014)... Community Health Center of Snohomish County (CHC), a non-profit ... released an article designed to educate patients about the ... 1983, the health center has a strong focus on ... barriers to obtaining high quality yet affordable healthcare services. ... click here: http://www.chcsno.org/locations.ashx?p=1099 , The article begins ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 According to court ... principal owner of The Marcal Group (TMG), met ... Group (HMG). A contract, as well a broad project outline, ... website, as well as branding services and marketing. ... completed by HMG throughout the course of the project, praise ...
(Date:7/28/2014)... July 28, 2014 TherapySites, ... health professionals, announced today its affiliation with the ... This new relationship allows TherapySites to continue to extend ... benefits and promotional offers. , “There has been a ... today. With nearly 3 billion Internet users, it ...
Breaking Medicine News(10 mins):Health News:IRS Caps Fines on Uninsured Americans at $12K for Family of 5 2Health News:Community Health Center of Snohomish Releases Article Focusing on Educating the Chronically Ill About Chronic Disease Management 2Health News:Community Health Center of Snohomish Releases Article Focusing on Educating the Chronically Ill About Chronic Disease Management 3Health News:Calko Medical Center Loses Website Twice over Non-Payment, According to Court Documents 2Health News:TherapySites (Websites for Therapists) Partners with the Illinois Association for Marriage and Family Therapy 2
... is becoming the norm of today’s stress related life ... and turning towards fruits //and vegetables. As constant articles ... these two elements (Yoga and Healthy Eating) to help ... for specific diseases, like cancer and heart disease. ...
... Research by the medicinal plant research centre at ... in the journal Phytotherapy Research found that green ... certain brain,enzymes that bring on Alzheimer's Disease. Alzheimer's ... an estimated 10 million people worldwide., ,According ...
... who have children at an older age may increase ... life. ,Researchers based their analysis on records ... 1989 and 2001 with a diagnosis of schizophrenia or ... association between the fathers' age at conception and their ...
... young adults who have poor functioning of a key ... blockages in their arteries.// ,The researchers looked specifically ... blood vessels in the arteries, called endothelial functioning, affects ... 2,000 people were followed from childhood. Over the 21 ...
... is the most common cancer among men, affecting about one ... cases // of the disease are diagnosed every year and ... ,New research shows men who are diagnosed with abnormal cells ... risk of developing prostate cancer within one year. The study, ...
... of red wine each day could keep keep lung cancer ... lung cancer and 187 patients requiring routine surgery between 1999 ... their early 60s. Patients were asked about their diet, smoking ... drank each day. They were asked to specify if they ...
Cached Medicine News:
(Date:7/25/2014)... 25, 2014  In today,s marketplace, launching multiple products ... - as is managing a portfolio of products in ... possible - or even preferable - to pool resources ... you combine resources and activities, and what marketing and ... are just a few of the dilemmas facing pharmaceutical ...
(Date:7/25/2014)... COSTA MESA, Calif. , July 25, 2014 /PRNewswire-iReach/ ... Peter Nieto as the new Vice President ... industry for over 30 years in a number of ... CROs in the industry. These positions were primarily related ... has obtained over the past 30 years makes him ...
(Date:7/25/2014)... 25, 2014  Acsis Inc., the market leader ... solutions, has recently posted an article, "Future ... and future needs for companies, extended supply chain, ... chain model no longer work today.  The article ... growth of mobile technology, machine to machine (M2M) ...
Breaking Medicine Technology:Using Promotional Efficiency to Support Multiple Products and Indications in the Pharmaceutical Marketplace 2Contract Research Organization WCCT Global Welcomes Peter Nieto as Vice President of Business Development 2Acsis Addresses Questions on the Modern Supply Chain 2
Ergotec Vetriretinal Instrument System. Ultra-fine 2.8 mm jaws. Angled 55 degrees. 20 gauge shaft. 25 mm in length with black tip. Overall length from rear rotation knob to tip....
Triangular shaped tips. Marked for 5 mm and 10 mm tucks. Round knurled handle with polished finish....
Angled shafts with 12 mm scaled jaws. 1 mm teeth on one jaw fit into holes on the other jaw. Slide lock and serrated handle with polished finish. Left. Most popular size or model....
Angled shafts with 11 mm long tips. Jaws have longitudinal meshing serrations. Slide lock and serrated handle with polished finish....
Medicine Products: