Navigation Links
Illegal 'Bath Salts' Mimic Cocaine in the Brain: Study
Date:7/26/2012

THURSDAY, July 26 (HealthDay News) -- Street drugs called "bath salts" have a similar effect in the brain as cocaine and carry the same risk for abuse and addiction, a new study in mice has found.

Bath salts are synthetic stimulants that have become increasingly popular among recreational drug users in recent years. (The substances have nothing to do with the crystals you might sprinkle in a bathtub.)

In the new study of adult mice, University of North Carolina researchers found evidence that the effects of the bath salt mephedrone on the brain's reward circuits are comparable to similar doses of cocaine.

The mice were implanted with brain-stimulating electrodes and trained to run on a wheel in order to give themselves a reward, which was direct stimulation of the brain pathways involved in reward perception.

The technique, called "intracranial self-stimulation" has been used in experiments since the 1950s, according to researchers. Prior intracranial self-stimulation studies have shown that one of the characteristics of addictive drugs is to make self-stimulation more pleasurable.

The researchers measured the rodents' wheel spinning efforts before, during and after they were given various doses of cocaine or mephedrone. Like cocaine, mephedrone made intracranial self-stimulation more rewarding for the mice.

The study was released online in advance of publication in an upcoming print issue of the journal Behavioural Brain Research.

The findings support the idea that mephedrone and other bath salts may have a significant addiction risk, said study leader Dr. C.J. Malanga, an associate professor of neurology, pediatrics and psychology at the University of North Carolina School of Medicine.

"The effects of mephedrone on the brain's reward circuits are comparable to similar doses of cocaine," Malanga said in a university news release. "As expected our research shows that mephedrone likely has significant abuse liability."

On July 9, President Barack Obama signed a law banning bath salts containing mephedrone or another stimulant, MDPV, in the United States.

Experts caution that while animal studies may be useful, they often don't reproduce the same results in humans.

More information

The U.S. National Institute on Drug Abuse has more about bath salts.

-- Robert Preidt

SOURCE: University of North Carolina Health Care, news release, July 23, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. San Francisco Bath Salt Company Clears Air About Bath Salt Confusion – Zombies Beware!
2. Local Woodinville Contractor, Washington State Kitchen and Bath, Combats Toxic Mold, Adhering to the Toughest Mold Protection Standards in the Nation with New Promotion
3. Synthetic stimulants called bath salts act in the brain like cocaine
4. Effects of High Blood Pressure Drug May Mimic Celiac Disease
5. Scientists Use Stem Cells to Mimic Huntingtons Disease
6. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
7. Chronic cocaine use triggers changes in brains neuron structure
8. Anti-cocaine vaccine described in Human Gene Therapy Journal
9. Neurons that control overeating also drive appetite for cocaine
10. Study Suggests Vaccine May Help Kids With Brain Cancer
11. Study reveals how cancer drug causes diabetic-like state
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/24/2017)... (PRWEB) , ... September 24, 2017 , ... The Tuscany ... on TripAdvisor and one of Provo's premier boutique resorts, is planning on re-opening the ... the resort after devastating Hurricanes Irma and more recently Hurricane Maria, and the staff ...
(Date:9/24/2017)... ... September 24, 2017 , ... “The Messiah 8 with the ... texts to firsthand experiences. “The Messiah 8 with the 3rd Anti Christ” is the ... I’ve tried to look at all the angles of life,” Velazquez states, “I always ...
(Date:9/24/2017)... ... September 24, 2017 , ... “Star of Bethlehem Study”: is ... Study” is the creation of published author, Duane Engdahl, an investigator who had has ... Faith Publishing, Duane Engdahl’s new book is a thought-provoking essay an event so significant ...
(Date:9/23/2017)... ... September 23, 2017 , ... A September 5 ... Robert Kushner, director of Chicago’s Center for Lifestyle Medicine at Northwestern Medicine. While ... article notes that the center routinely recommends weight loss surgeries for patients who ...
(Date:9/23/2017)... ... ... Can't Win Them All”: the story of an entrepreneur and a family man whose ... lives of young athletes. “You Can't Win Them All” is the creation of ... small town in Northern Ontario, Canada. He is an entrepreneur who manages to ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... , Sept. 6, 2017   PDI , a leader ... will host an educational session focused on the role ... (CLABSI) prevention at the 2017 Annual Scientific Meeting of ... take place at the Phoenix ... from Sept. 16-19, will also feature PDI,s Prevantics® ...
(Date:9/5/2017)... Sept. 5, 2017  Getinge, a leading global ... vibrant charitable donation program -- "Color for the ... heart defect research by The Children,s Heart Foundation. ... general public are encouraged to download a coloring ... completed artwork to the gallery on the website. ...
(Date:9/1/2017)... WHIPPANY, N.J. , Sept. 1, 2017  Bayer will ... at the European Society for Medical Oncology (ESMO) 2017 Congress, ... studies presented will include new preclinical and clinical data on ... from two earlier pipeline projects. ... of the best minds in cancer research at ESMO," said ...
Breaking Medicine Technology: