Navigation Links
Illegal 'Bath Salts' Mimic Cocaine in the Brain: Study
Date:7/26/2012

THURSDAY, July 26 (HealthDay News) -- Street drugs called "bath salts" have a similar effect in the brain as cocaine and carry the same risk for abuse and addiction, a new study in mice has found.

Bath salts are synthetic stimulants that have become increasingly popular among recreational drug users in recent years. (The substances have nothing to do with the crystals you might sprinkle in a bathtub.)

In the new study of adult mice, University of North Carolina researchers found evidence that the effects of the bath salt mephedrone on the brain's reward circuits are comparable to similar doses of cocaine.

The mice were implanted with brain-stimulating electrodes and trained to run on a wheel in order to give themselves a reward, which was direct stimulation of the brain pathways involved in reward perception.

The technique, called "intracranial self-stimulation" has been used in experiments since the 1950s, according to researchers. Prior intracranial self-stimulation studies have shown that one of the characteristics of addictive drugs is to make self-stimulation more pleasurable.

The researchers measured the rodents' wheel spinning efforts before, during and after they were given various doses of cocaine or mephedrone. Like cocaine, mephedrone made intracranial self-stimulation more rewarding for the mice.

The study was released online in advance of publication in an upcoming print issue of the journal Behavioural Brain Research.

The findings support the idea that mephedrone and other bath salts may have a significant addiction risk, said study leader Dr. C.J. Malanga, an associate professor of neurology, pediatrics and psychology at the University of North Carolina School of Medicine.

"The effects of mephedrone on the brain's reward circuits are comparable to similar doses of cocaine," Malanga said in a university news release. "As expected our research shows that mephedrone likely has significant abuse liability."

On July 9, President Barack Obama signed a law banning bath salts containing mephedrone or another stimulant, MDPV, in the United States.

Experts caution that while animal studies may be useful, they often don't reproduce the same results in humans.

More information

The U.S. National Institute on Drug Abuse has more about bath salts.

-- Robert Preidt

SOURCE: University of North Carolina Health Care, news release, July 23, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. San Francisco Bath Salt Company Clears Air About Bath Salt Confusion – Zombies Beware!
2. Local Woodinville Contractor, Washington State Kitchen and Bath, Combats Toxic Mold, Adhering to the Toughest Mold Protection Standards in the Nation with New Promotion
3. Synthetic stimulants called bath salts act in the brain like cocaine
4. Effects of High Blood Pressure Drug May Mimic Celiac Disease
5. Scientists Use Stem Cells to Mimic Huntingtons Disease
6. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
7. Chronic cocaine use triggers changes in brains neuron structure
8. Anti-cocaine vaccine described in Human Gene Therapy Journal
9. Neurons that control overeating also drive appetite for cocaine
10. Study Suggests Vaccine May Help Kids With Brain Cancer
11. Study reveals how cancer drug causes diabetic-like state
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... Durham, NC (PRWEB) , ... May 04, 2016 ... ... healthcare professionals in medical coding, billing and compliance. In upcoming months, AudioEducator has ... on various specialties. Every conference is designed to give complete compliance know-how and ...
(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... ... Patient 2016, a powerful cellular therapy software application that helps blood and ... to patients. , Since Transtem’s initial launch, Mediware has continued to enhance core ...
(Date:5/4/2016)... ... ... Fertility Centers of New England announced today the opening of their newest location ... access to care for patients seeking fertility treatment in Maine. “We are delighted to ... Portland,” said Fertility Centers of New England President and CEO, Joseph A. Hill, M.D. ...
(Date:5/3/2016)... , ... May 04, 2016 , ... ... 40 national and global construction firms representing the Construction Industry Safety Initiative (CISI) ... forces with one purpose: to inspire everyone in the industry to be leaders ...
(Date:5/3/2016)... , ... May 03, 2016 , ... ... Business Journal, patients report dissatisfaction with numerous issues related to medical care in ... with billing, and poor bedside manner from hospital staff. Commenting on this article, ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... May 3, 2016 ... dass sie einen entscheidenden Meilenstein durch diese ... Aufruf zum Handeln, um Patientenresultate  bei Verdauungs- ... zu Fortschritten im Verständnis der Hepatischen Enzephalopathie ... Bewusstsein für Hepatische Enzephalopathie in der Öffentlichkeit ...
(Date:5/2/2016)... May 2, 2016  While nearly three-quarters of Americans ... have on their health, only about half report taking ... the results of a new survey announced today by ... start of National Osteoporosis Month, Hologic is raising awareness ... nearly 56 million Americans. Osteoporosis is a ...
(Date:4/29/2016)... , April 29, 2016 ... Review, H1 2016" market research report that provides ... with comparative analysis at various stages, therapeutics assessment ... of administration (RoA) and molecule type, along with ... It also reviews key players involved in the ...
Breaking Medicine Technology: