Navigation Links
Identified 2 new genes involved in the more aggressive prostate cancer
Date:5/13/2014

A study by the Columbia University Nova York, in collaboration with the Catalan Institute of Oncology , Belvitge Biomedical Research Institute (ICO-IDIBELL) has identified two new genes that lead to more aggressive forms of prostate cancer. The work done by Alvaro Aytes under the direction of Cory Abate-Shen , director of the Herbert Irving Comprehensive Cancer Center of the Columbia University, has been published in the latest issue of Cancer Cell.

Prostate cancer

Prostate cancer is the most common in men in Europe( accounts for 20% of all male tumors). The incidence is about 60 new cases per 100,000 inhabitants per year.

A tumor closely associated with old age, and most cases is diagnosed between 70 and 80 years. The progressive aging of the population has made it one of the tumors that has increased in recent decades. Survival is quite high: according to Oncology Master Plan, 84 % of patients are alive five years after diagnosis.

Identify high-risk patients

In a significant proportion of patients the prostate tumor has a not very aggressive behavior, which does not compromise the health and quality of life of the affected. Also, being a tumor that usually occurs in old age, often the person dies with the tumor but not as a result of this.

It is therefore necessary to develop tools to predict which prostate tumors are clinically relevant and potentially lethal. This would open the door to customize treatments and avoid certain therapies and , therefore, avoid side effects to patients that do not need it, further reducing healthcare costs.

Two new genes in the spotlight

The study published in Cancer Cell identified two genes, the FOXM1 and CENPF, if they are abnormally activated simultaneously, lead to more aggressive and life threatening forms of prostate cancer .

A new feature of the study is that computer algorithms were used to generate netw
'/>"/>

Contact: Arantxa Mena
amena@idibell.cat
0034-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Predictors identified for rehospitalization among post-acute stroke patients
2. 2 repressor genes identified as essential for placental development
3. Possible new cancer treatment identified
4. Gene Behind Psoriasis Identified, Researchers Say
5. A microRNA prognostic marker identified in acute leukemia
6. Early biomarker for pancreatic cancer identified
7. The cells petrol pump is finally identified
8. Mutations in JAK3 gene identified in subtype of lymphoma provide potential drug target
9. New cerebellar ataxia gene identified in dogs
10. Misidentified and contaminated cell lines lead to faulty cancer science
11. Germ Culprits in Moldy, Water-Damaged Buildings Identified
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Identified 2 new genes involved in the more aggressive prostate cancer
(Date:8/30/2014)... 2014 Hands On Mobile ... offers the complete spa experience combining elegant decor, ... the most important ingredient of all, states Marla ... pro's! People will enjoy the get-away feel, without ... website reads, "Step into the spacious, luxurious spa ...
(Date:8/30/2014)... 2014 Daily Gossip magazine reveals in ... and panic attacks under control with a simple and ... describes this new method as an anxiety recovery ... and overcome general anxiety related disorders. , What ... fact that it can be accessed by users from ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 The ... Nutrition and Pharameuticals. Nutraceuticals is a source of ... ingredients from natural food sources. Nutraceutical ingredients have ... to the human body. Nutraceutical health products include ... fortified foods and more. Although nature is the ...
(Date:8/30/2014)... Hicksville, NY (PRWEB) August 30, 2014 ... Organizations throughout the planet has been one of ... in order to create a positive impact around ... aesthetics and staffed with top trained executives and ... millions of people worldwide. Vital statistics demonstrate ...
(Date:8/30/2014)... TX (PRWEB) August 30, 2014 ... Disruptor Industry, 2009-2019 is a professional and in-depth ... industry. The report firstly reviews the basic information ... manufacturing technology. The report then explores global and ... product specification, capacity, Production value, and market share ...
Breaking Medicine News(10 mins):Health News:Hands On Mobile Massage and Spa of Long Island Now Offers a Spa-on-wheels 2Health News:Panic Away Review Reveals New Natural Remedy for Anxiety Patients 2Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 2Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 3Health News:A Granular Analysis of the Nutraceutical Ingredients Market by Transparency Market Research 4Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 3Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 4
... The earliest known case of coronary artery disease has been ... lived between 1580 and 1550 B.C., and died in her ... scans found that this wasn,t a unique case. About 45 ... an accumulation of plaque in arteries. The findings ...
... a genetic characteristic of metastatic prostate cancer that defines ... published in Cancer Discovery , the newest journal ... debut at the AACR 102nd Annual Meeting 2011, held ... an investigator of the Howard Hughes Medical Institute and ...
... laboratory and epidemiologic data to find that men using the ... prostate cancer. The scientists say further research about the ... ones that work the same way, to treat the cancer. ... for centuries in folk medicine and for decades to treat ...
... bladder cancer risk and to the length of protective caps ... of Texas MD Anderson Cancer Center reported today at the ... telomeres, guard against chromosomal damage and genomic instability that can ... single point of variation in the genome strongly associated with ...
... use has been linked to thicker arteries, possibly contributing to ... of twin veterans. The data is being presented Tuesday, April ... Orleans. Depression can heighten the risk for heart disease, ... is separate and independent from depression itself, says first author ...
... hedgehog pathway inhibitor demonstrated efficacy in preventing and treating ... syndrome, a rare inheritable disease, according to Phase II ... held April 2-6. In 1996, Ervin Epstein Jr., ... Institute, and colleagues identified the site of the mutation ...
Cached Medicine News:Health News:Mummies Show Heart Disease Is an Ancient Problem 2Health News:Heart drug cuts prostate cancer risk; holds potential for therapeutic use 2Health News:Heart drug cuts prostate cancer risk; holds potential for therapeutic use 3Health News:Genetic variation cuts bladder cancer risk, protects chromosome tips 2Health News:Genetic variation cuts bladder cancer risk, protects chromosome tips 3Health News:Antidepressants linked to thicker arteries 2Health News:New inhibitor prevented lesions, reduced tumor size in basal cell cancer 2Health News:New inhibitor prevented lesions, reduced tumor size in basal cell cancer 3
(Date:8/29/2014)... -- ChemImage will present a workshop focused on hyperspectral ... Science Society,s 22 nd International Symposium on ... .  Forensic Scientists will be in attendance ... can bring to examination procedures. ... Development at ChemImage, will host a workshop during ...
(Date:8/29/2014)... -- In part four of a blog series ... a strategic asset, Mary Baxter, MBA, RPh ., ... Innovation Delivery Solutions business, discusses how expanding patient access ... patients. "Every hospital pharmacist knows that filling ... in a value-based healthcare world," Baxter says. "For the ...
(Date:8/29/2014)... Calif. , Aug. 29, 2014  Pacific Medical ... its new website design . The main website, ... that showcases the company,s new services and content relevant ... implementing a new streamlined design, viewers can now better ... for health care practices and create a more visible ...
Breaking Medicine Technology:ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4PMDS Announces New Website 2
... Implementation of electronic medical records (EMR) by healthcare providers ... so many reports, the determining factor responsible for this ... reported by USA Today, upfront costs (which include purchasing ... $36,000 per physician. In addition, the learning curve for ...
... N.J., Oct. 30 Novo Nordisk Inc. announced the ... hemophilia(TM) campaign through a rebranded Web site and ... face many daily challenges, and Novo Nordisk is committed ... a lifetime of possibilities. , These new online resources ...
Cached Medicine Technology:Electronic Medical Record System and More 2Electronic Medical Record System and More 3Novo Nordisk is Changing Possibilities in Hemophilia 2Novo Nordisk is Changing Possibilities in Hemophilia 3
Used for stone manipulation and removal in the urinary tract. The hollow shaft allows protected delivery of a laser fiber to an entrapped stone for fragmentation of the stone. Supplied sterile in pee...
... Tipless Design, ZeroTip basket features ... negotiation and close stone approximation., Flexible ... deflection for efficient retrieval of calyceal ... passed through a 3.6Fr working channel, ...
... Tip 12 Inch , 20 inch,PVC, Length ... Available in 3,4,5 6Fr. These top quality ... flexible polymer material and have standard screw ... They are manufactured to the highest standards. ...
Bard Coude-Tip Latex Urethral Catheter, Two Eyes (Tiemann Model)...
Medicine Products: