Navigation Links
Identified 2 new genes involved in the more aggressive prostate cancer
Date:5/13/2014

A study by the Columbia University Nova York, in collaboration with the Catalan Institute of Oncology , Belvitge Biomedical Research Institute (ICO-IDIBELL) has identified two new genes that lead to more aggressive forms of prostate cancer. The work done by Alvaro Aytes under the direction of Cory Abate-Shen , director of the Herbert Irving Comprehensive Cancer Center of the Columbia University, has been published in the latest issue of Cancer Cell.

Prostate cancer

Prostate cancer is the most common in men in Europe( accounts for 20% of all male tumors). The incidence is about 60 new cases per 100,000 inhabitants per year.

A tumor closely associated with old age, and most cases is diagnosed between 70 and 80 years. The progressive aging of the population has made it one of the tumors that has increased in recent decades. Survival is quite high: according to Oncology Master Plan, 84 % of patients are alive five years after diagnosis.

Identify high-risk patients

In a significant proportion of patients the prostate tumor has a not very aggressive behavior, which does not compromise the health and quality of life of the affected. Also, being a tumor that usually occurs in old age, often the person dies with the tumor but not as a result of this.

It is therefore necessary to develop tools to predict which prostate tumors are clinically relevant and potentially lethal. This would open the door to customize treatments and avoid certain therapies and , therefore, avoid side effects to patients that do not need it, further reducing healthcare costs.

Two new genes in the spotlight

The study published in Cancer Cell identified two genes, the FOXM1 and CENPF, if they are abnormally activated simultaneously, lead to more aggressive and life threatening forms of prostate cancer .

A new feature of the study is that computer algorithms were used to generate netw
'/>"/>

Contact: Arantxa Mena
amena@idibell.cat
0034-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Predictors identified for rehospitalization among post-acute stroke patients
2. 2 repressor genes identified as essential for placental development
3. Possible new cancer treatment identified
4. Gene Behind Psoriasis Identified, Researchers Say
5. A microRNA prognostic marker identified in acute leukemia
6. Early biomarker for pancreatic cancer identified
7. The cells petrol pump is finally identified
8. Mutations in JAK3 gene identified in subtype of lymphoma provide potential drug target
9. New cerebellar ataxia gene identified in dogs
10. Misidentified and contaminated cell lines lead to faulty cancer science
11. Germ Culprits in Moldy, Water-Damaged Buildings Identified
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Identified 2 new genes involved in the more aggressive prostate cancer
(Date:12/25/2014)... (PRWEB) December 25, 2014 Plugin creators ... ProFire 5k. A fully customizable business presentation tool made ... “Adding the ProFire 5k business tool, users can now ... Austin, CEO of Pixel Film Studios. “ProFire 5k gives ... style to add professionalism to a presentation” , Pixel ...
(Date:12/25/2014)... CA (PRWEB) December 25, 2014 Each ... visits and 2 million hospital admissions across the nation ... Prevention ). The CDC’s National Hospital Ambulatory Medical ... through a survey conducted in 2010. They estimated that ... visits that resulted in a primary diagnosis of broken ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping ... items. During the holiday season, AlignLife looks forward to their ... says Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It brings our ... that we are able to give kids toys for Christmas ... for the generosity of our patients." , The 70 toys ...
(Date:12/24/2014)... finds applications in a large number of fields of ... and research for metabolic and genetic disorders. It is ... techniques for the discovery and development of cancer biomarkers. ... growing worldwide. In 2012, there were 14.1 million new ... people living with cancer (within five years of diagnosis) ...
(Date:12/24/2014)... Recently, iFitDress.com, a famous dress manufacturer and retailer, has ... All these items are brand new; they are made by ... with the new range of high quality prom gowns. A ... designs are made according to the latest trends. For years, ... from the company is handpicked by skilled tailors. , In ...
Breaking Medicine News(10 mins):Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 3Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 4Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2Health News:Global Epigenetics Market Was Valued at $413.24 Million in 2014 - New Research Report by MarketsandMarkets 2Health News:Global Epigenetics Market Was Valued at $413.24 Million in 2014 - New Research Report by MarketsandMarkets 3Health News:Many Prom Dresses under 150 from Well-known Dress Manufacturer iFitDress.com 2
... RICHMOND, Va., Feb. 6 A new statewide ... using,tobacco settlement and tobacco tax revenue for programs ... smokers quit., The poll of 500 Virginia ... American Heart Association, American Lung Association and,the Campaign ...
... German . , Scientists from the University of Bonn ... than 100 million years ago. They want to find out how ... In actual fact such gigantic animals should not have existed. The ... ,Proceedings of the Royal Society B,. , Take 200 milligrammes of ...
... large, multi-institutional study comparing the accuracy of positron emission ... of lung nodules found that PET was far more ... malignant. , CT and PET have been widely used ... malignant, said James W. Fletcher, professor of radiology at ...
... Feb. 6 As it prepares to mark,its ... solutions,to the healthcare industry, Sentillion, the company that ... In Q4, Sentillion,added 10 new customers in North ... licenses and brought 17,000 additional users,live across its ...
... Healthy Lifestyles at N.C. ... Department of Transportation, RALEIGH, ... building healthy lifestyles in North Carolina by making a,$1.5 million ... North Carolina State Health Plan, will fund for three years,a ...
... ... markets -, WOONSOCKET, R.I., Feb. 6 If you have ever been ... or other vehicular,emergency, you are probably familiar with the feeling of relief that ... has,provided that help and relief to more than a million drivers in need ...
Cached Medicine News:Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 2Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 3Health News:Bonn scientists simulate dinosaur digestion in the lab 2Health News:Bonn scientists simulate dinosaur digestion in the lab 3Health News:PET outperforms CT in characterization of lung nodules 2Health News:Sentillion Announces Strong Q4 Performance; Signs 10 New Customers; Sells 95,800 Licenses 2Health News:Sentillion Announces Strong Q4 Performance; Signs 10 New Customers; Sells 95,800 Licenses 3Health News:AstraZeneca Gives $1.5 million to Support North Carolina Worksite Wellness Project 2Health News:AstraZeneca Gives $1.5 million to Support North Carolina Worksite Wellness Project 3Health News:CVS Samaritan Van Program Celebrates 30 Years of Helping Motorists on the Nation's Highways 2Health News:CVS Samaritan Van Program Celebrates 30 Years of Helping Motorists on the Nation's Highways 3Health News:CVS Samaritan Van Program Celebrates 30 Years of Helping Motorists on the Nation's Highways 4
(Date:12/24/2014)... LONDON , December 24, 2014 ... to grow at an average rate of 8.1%. The ... volume. Hip, knee and spine surgeries are the common ... economies they have a lower penetration. Increased number of ... of composites. Non-metallic orthopedic devices have gained popularity in ...
(Date:12/24/2014)... Dec. 23, 2014 Echo Therapeutics, Inc. ... company focused on skin permeation, continuous glucose monitoring ... W. Hollander has been appointed Chief Executive ... more than 20 years of experience in the ... most recently served as Vice President, Business Development, ...
(Date:12/24/2014)... SAN DIEGO , Dec. 23, 2014 ResMed ... a significant patent infringement action against Chinese medical device manufacturer ... Commission (ITC) ruled today that BMC,s masks listed below infringe ... advertising, or selling these masks in the United ... , iVolve N2 nasal mask , Willow nasal pillows ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2
... a division of Wyeth (NYSE: WYE ), ... which showed that bazedoxifene/conjugated,estrogens reduced the number and ... up to 80 percent, when compared with placebo. ... Annual Meeting,also showed that bazedoxifene/conjugated estrogens improved symptoms ...
... 4 A new scientific,review released today by ... evidence of benefit is lacking for many common ... dietary supplement,ingredients, a common surgical procedure, and injected ... chondroitin, over-the-counter,dietary supplement ingredients that are used widely ...
Cached Medicine Technology:Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens 2Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens 3Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens 4Evidence of Benefit Lacking for Many Common Ways of Treating Osteoarthritis of the Knee 2
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: