Navigation Links
Ibuprofen associated with slower lung function decline in children with cystic fibrosis
Date:11/30/2007

Treatment with ibuprofen is associated with a significantly slower rate of decline in lung function in children and adolescents with cystic fibrosis, according to a new study.

Researchers found that patients with cystic fibrosis (CF) who took high doses of ibuprofen had a 29 percent reduction in loss of lung function compared to those who did not use the anti-inflammatory drug twice daily over a period of two to seven years.

It is fairly evident that the lung damage that occurs in cystic fibrosis is due to inflammation, and that this lung damage is what shortens the lives of these patients, said lead researcher Michael W. Konstan, M.D., Director of the Cystic Fibrosis Center at Rainbow Babies and Children's Hospital, and a professor of pediatrics at Case Western Reserve University School of Medicine in Cleveland. Since ibuprofen is an anti-inflammatory drug, we presume that it works by decreasing inflammation in the lung, thereby slowing damage.

The study, which concluded that the benefits of ibuprofen therapy outweigh the small risk of gastrointestinal bleeding, appears in the first issue for December 2007 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Cystic fibrosis is a genetic disorder that causes mucus to be thick and sticky. The mucus clogs the lungs, which causes breathing problems and makes it easy for bacteria to grow. The persistence of bacterial infections leads to chronic inflammation, causing lung damage, which eventually proves fatal.

Dr. Konstan led a clinical trial 12 years ago that found ibuprofen reduced the loss of lung function in CF patients, but questions have remained about the safety of regular high-dose ibuprofen use, which in some cases can lead to gastrointestinal bleeding. This study showed that gastrointestinal bleeding was rare, with an annual incidence of 0.37 percent in those taking ibuprofen, compared with 0.14 percen
'/>"/>

Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Ibuprofen can slow lung disease in children with cystic fibrosis, Canadian study shows
2. Albemarle to Increase Price of Ibuprofen
3. New study shows promise in reducing surgical risks associated with surgical bleeding
4. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
5. Study, meta-analysis examine factors associated with death from heatstroke
6. Increased distance to physician associated with thicker skin cancer at diagnosis
7. Minorities more likely to have sleep durations associated with increased mortality
8. Income inequality associated with overnourishment and undernourishment in India
9. Maternal depression and controlling behavior associated with increased stress response in infants
10. Nurses describe dedication, frustration associated with their jobs
11. New research shows ACTOS is associated with a 38 percent lower risk of heart attack

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/8/2009)...itical legislation would strengthen Medicare, impr...v. 8 SUMMARY: Yesterd...ed critical health care reform legislation that wo...mination by insurance companies that prices millio... ,, The Affordable Health Care for America Ac...
(Date:11/8/2009)... UCW Academy of Health holds open ... Victoria, BC (Vocus) November 8, 2009 -- UCW Aca...areer in British Columbia’s health care indu...nesday, November 25, 2009. , ,UCW Academy of Heal...tration, nursing and social services, designs its ...
(Date:11/8/2009)...HINGTON, Nov. 7 Tonight...e Health Care for America Act, landmark health ref...s access to quality, affordable, stable and secure...ks down on some of the insurance industry,s worst ...ricans and cut the deficit by $104 billion over te...
(Date:11/8/2009)... Men’s Health Network (MHN) ...h risks, especially those linked to exposure to ch...tary service. Bladder cancer is one of those cance...specially those who once smoked or currently smoke... DC (PRWEB) November 8, 2009 -- Men’s Health...
(Date:11/8/2009)...tion,s largest network of Hispanic health advocate...form in 2009 ,, WASHINGTON, Nov. 7 /PRNewswire...ntatives showed they have heard the voice of Ameri...e for America Act. Now the Senate must deliver, wi...are reform," said Dr. Jane L. Delgado, President a...
Breaking Medicine News(10 mins):Health News:AARP NY Praises House Passage of Health Care Reform Bill 2Health News:AARP NY Praises House Passage of Health Care Reform Bill 3Health News:AARP NY Praises House Passage of Health Care Reform Bill 4Health News:College Invites Public to Explore Career Options in Health Care 2Health News:Democratic National Committee Chairman Tim Kaine Issues Statement Praising the House of Representative's Historic Vote to Pass Health Insurance Reform 2Health News:Democratic National Committee Chairman Tim Kaine Issues Statement Praising the House of Representative's Historic Vote to Pass Health Insurance Reform 3Health News:Veterans' Day Reminder from Men's Health Network: Pay Attention to Bladder Cancer Symptoms and Risk Factors 2Health News:Veterans' Day Reminder from Men's Health Network: Pay Attention to Bladder Cancer Symptoms and Risk Factors 3Health News:National Alliance for Hispanic Health President and CEO Applauds House Action, Calls on Senate to Pass Health Reform in 2009 2
...nister Anbumani Ramadoss said that India is crowne...necessary measures to implement a national program...sease, //stroke and diabetes. He said this in the ... The programme’s main aim is to reduce the ad...
...global network of virus, spyware and spam analysis...n letter that is spreading across the internet.// .... The emails claim that some brands of lipstic...pho has asked the users to simply delete the email...
...upplementation during pregnancy can reduce the inc...ly preeclampsia related//, reports a study publish...y. Preeclampsia, a pregnancy-related complicat...en. If left unattended, the condition can worsen f...
...nada warned the women especially the pregnant wome...e anti depressant drugs known as selective seroton.... Drugs like Prozac and Paxil may cause a conditio...l condition among babies. But sudden discontinual ...
...en known for a long time that smoking is associate...r, heart attacks and emphysema. A new study has hi...els of Streptococcus pneumonia, a bacteria that ca...Let us hope that this study at least helps people ...
...arried in eight Ethiopian villages for two years f...icient to nip infection causing trachoma, which ha... A previous study in one Tanzanian village had se...nfection relapses after two years. “I think ...
Other Medicine News:
(Date:11/6/2009)...all/ -- Boston Scientific Corporation (NYSE: BSX ... in principle with the U.S. Department of Justice ...Guidant subsidiary in 2005. The alleged conduct a...ic,s 2006 acquisition of Guidant. ,, Boston Sci...by the U.S. Attorney,s Office in Minneapolis into ...
(Date:11/6/2009)...-- With his proposed health care reform plan, Pres...ame-brand prescription drug costs by 50 percent fo...erage gap, universally known as the "donut hole." ...ng and feel it,s a promising start to health care ...nt a revised program that completely eliminates th...
(Date:11/6/2009)...Newswire/ -- Chimerix, Inc., a biopharmaceutical c...eutics to address life-threatening diseases, prese...ead antiviral compound, CMX001, to the World Healt...y Initiative (GHSI). CMX001 is a broad-spectrum a...f smallpox, as well as other serious viral infecti...
Breaking Medicine Technology:Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 2Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 3Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 4Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 5Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 6Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 7Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 8Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 9Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 10Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 11Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 12Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 13Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 14Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 15Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 16Boston Scientific Announces Agreement With DOJ On Pre-Acquisition Investigation of Guidant 17Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 2Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 3Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox 2Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox 3Satellite Healthcare Tees Up With the National Kidney Foundation in Santa Cruz CA 5343 1Satellite Healthcare Tees Up With the National Kidney Foundation in Santa Cruz CA 5343 2Reportlinker Adds Computer Assisted Coding Of Medical Information Market Shares Strategies and Forecasts 2008 to 2014 5340 1Reportlinker Adds Computer Assisted Coding Of Medical Information Market Shares Strategies and Forecasts 2008 to 2014 5340 2Reportlinker Adds Computer Assisted Coding Of Medical Information Market Shares Strategies and Forecasts 2008 to 2014 5340 3Reportlinker Adds Computer Assisted Coding Of Medical Information Market Shares Strategies and Forecasts 2008 to 2014 5340 4Hospira Celltrion Enter Business Cooperation Agreement to Develop and Market Biogeneric Drugs 5337 1Hospira Celltrion Enter Business Cooperation Agreement to Develop and Market Biogeneric Drugs 5337 2Hospira Celltrion Enter Business Cooperation Agreement to Develop and Market Biogeneric Drugs 5337 3
...for Treating Motor System Disorders, LA JOLLA, Ca...mall,molecule currently in clinical development by...r the treatment of acute migraine headache, was sh...ersing or preventing muscle,spasticity and rigidit...s,are commonly seen in Parkinson,s disease, multip...
... Pharmion Corporation,(Nasdaq: PHRM ) today anno...hase 3 clinical trial evaluating amrubicin, the Co...in the treatment of second-line small cell lung,ca...ter study will compare,amrubicin to topotecan, the...ent of SCLC in the US and EU. Enrollment in the st...
Other Medicine Technology:Tezampanel, TorreyPines Therapeutics' Lead Compound, Reduced Muscle Spasticity and Rigidity in Preclinical Study Conducted at University of California, San Diego 2Tezampanel, TorreyPines Therapeutics' Lead Compound, Reduced Muscle Spasticity and Rigidity in Preclinical Study Conducted at University of California, San Diego 3Tezampanel, TorreyPines Therapeutics' Lead Compound, Reduced Muscle Spasticity and Rigidity in Preclinical Study Conducted at University of California, San Diego 4Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer 2Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer 3Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer 4Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer 5
Iron/TIBC Reagent Set
Liquid HDL Cholesterol
Cholesterol/HDL
HDL Cholesterol
Medicine Products: