Navigation Links
IVF Treatments Often Work for Women Under 35
Date:1/14/2009

But success rate is much lower for those over 40 who want a baby, study says,,

WEDNESDAY, Jan. 14 (HealthDay News) -- Women under 35 who undergo six cycles of in vitro fertilization have up to an 86 percent chance of giving birth, a new study found.

But for women over 40, the odds are less than 50 percent -- in some cases, significantly less.

"IVF is a mainstay of the treatment of infertility, and it can overcome most causes of infertility for those under 40," said study senior author Dr. Alan S. Penzias, surgical director of Boston IVF, and an associate professor of obstetrics, gynecology and reproductive biology at Harvard Medical School.

But, he added, "Fertility is a function of age. It starts to decline at age 27, and the most pronounced decline is above age 40."

"Unfortunately, there's no test that shows when fertility starts to decline," said Dr. Jamie Grifo, program director for the New York University Langone Medical Center's fertility clinic, who added that this study could serve as a reminder to women to "be really thoughtful about the decisions you make about the reproductive process. Don't expect to be able to get pregnant at any time. You don't have to be pessimistic, but the older the patient, the lower the chance of success, unless a couple is willing to consider donor eggs."

The new study, published in the Jan. 15 issue of the New England Journal of Medicine, looked at IVF success in a different way. Traditionally, IVF success is reported as the number of pregnancies per cycle of IVF treatment, but that doesn't let couples know the exact odds of having a pregnancy that ends up with a healthy baby. And that information is exactly what people want to know, Penzias said.

"Couples really want to figure out how likely it is that they'll have a baby if they undergo IVF," he said.

To give people a better idea of the live-birth rates, Penzias and his colleagues followed more than 6,000 women undergoing IVF at a large center. Almost 15,000 cycles of IVF were completed. A cycle is the implantation of one or more eggs. Penzias said for this study, an average of 2.3 eggs were transferred for the first cycle and 2.8 for the sixth.

The overall live-birth rate after six cycles of IVF was between 51 percent and 72 percent. For women under 35, the rate was 65 percent to 86 percent. The rates differed, because not all women returned for all six cycles, the researchers said.

So, the researchers developed a best-case and worst-case scenario to account for these women. The highest number assumes that the women who stopped IVF treatments would have had a baby, and the lower number assumes that none of them would have. The actual number likely lies somewhere in between those two scenarios.

Penzias said that means that women under 35 who go through IVF have roughly the same chance of having a baby as someone who's a similar age in the general population.

The live-birth rate decreased as the age of the women increased, and women over 40 had only between a 23 percent to 42 percent chance of having a baby.

Overall, about 70 percent of the women had one baby, and less than 30 percent had twins. Fewer than 2 percent had triplets, according to the study.

"It's not a surprise to know that if you do more than one IVF cycle, you have a better chance of having a baby, but this study gives an indication of what one can expect if one is going to do IVF and try it multiple times," said Grifo, who added that the bottom line is, "that for any one woman, each cycle is either 100 percent or zero percent."

More information

To learn more about in vitro fertilization, visit the American Pregnancy Association.



SOURCES: Alan S. Penzias, M.D., surgical director, Boston IVF, and associate professor, obstetrics, gynecology and reproductive biology, Harvard Medical School, Boston; Jamie Grifo, M.D., program director for the New York University Langone Medical Center's fertility clinic, New York City; Jan. 15, 2009, New England Journal of Medicine


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Your Chemist Shop Offers Patients a Revolutionary Alternative to Other Hair Loss Treatments for Both Men and Women
2. Two Endometrial Cancer Treatments May Not Work
3. 38% of U.S. Adults Use Alternative Treatments
4. UK kidney cancer patients face toxic, out-dated treatments with little hope of change
5. Juva Skin Center's Laser Skin Treatments Take an Innovative Leap with Pixel CO2 Device
6. Precious metal could lead to next generation of cancer treatments
7. Novel treatments show improvements in survival and response rates for leukemia and lymphoma
8. Novel Treatments Demonstrate Improvements in Overall Survival and Response Rates in Difficult-To-Treat Forms of Leukemia and Lymphoma
9. Mayo Clinic identifies best treatments for long-term survival in brain tumor patients
10. Mayo Clinic Identifies Best Treatments for Long-Term Survival in Brain Tumor Patients
11. FDA Takes Closer Look at Wrinkle Treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... announced its strategic partnership with Connance, a healthcare industry leader providing predictive ... proven, proprietary technology combine to provide health systems, hospitals and ambulatory surgical ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ... , "Film editors can give their videos a whole new perspective by using the ... CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different presets ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs ... College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. ... treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. ...
(Date:6/25/2016)... City, Oklahoma (PRWEB) , ... June 25, 2016 ... ... helping both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic ... the Oklahoma City area —Johnson is one of the first doctors to perform ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
(Date:6/23/2016)... Ill. , June 23, 2016  In a startling report ... are failing their residents by lacking a comprehensive, proven plan to ... a definitive ranking of how states are tackling the worst ... to only four states – Kentucky , ... Vermont . Of the 28 failing states, three ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
Breaking Medicine Technology: