Navigation Links
IUD reduces the risk of cervical cancer

Intrauterine devices (IUDs) may protect against cervical cancer. This is the conclusion of the broadest epidemiological study to date in which has participated the research group in Viruses and Cancer of IDIBELL, published at The Lancet Oncology.

The results show that women who uses IUD halved the risk of developing cervical cancer compared to those that had not ever used. These results are contrary to popular belief that IUD could be a risk factor of cervical cancer. Previous studies on possible effects of IUDs use on the development of this cancer have yielded inconsistent results.

To assess the effects of IUD use on the risk of cervical human papillomavirus (HPV) infection and the risk of developing cervical cancer, Xavier Castellsagu, researcher of Virus and Cancer research group at IDIBELL and of the Cancer Epidemiological Research Program at the Catalan Institute of Oncology (ICO), and colleagues analysed data from ten case-control studies of cervical cancer done in eight countries, and 16 HPV prevalence surveys in women from 4 continents.

Findings were adjusted for confounding factors such as number of Papanicolaou (Pap) smears, number of sexual partners, and age at first intercourse, among others.

Reduces the risk by half

IUD use did not affect the risk of HPV infection, but was associated with a significantly lower risk of cervical cancer for both major cervical cancer types reducing the likelihood of developing squamous-cell carcinoma by 44% and adenocarcinoma or adenosquamous carcinoma by 54%.

Interestingly, the length of IUD use did not significantly alter cervical cancer risk. The risk was reduced by nearly half in the first year of use and the protective effect remained significant even after 10 years of use.

The authors say that "the associations found in our study strongly suggest that IUD use does not modify the likelihood of prevalent HPV infection [the cause of cervical cancer], but might affect the likelihood of HPV progression to cervical cancer."

They suggest a number of possible explanations for the protective effect of IUDs including that the process of device insertion or removal destroys precancerous lesions or that it induces chronic mucosal inflammation and a long lasting immune response, thereby reducing the likelihood of HPV progression.

As possible explanations for this protective effect of IUDs, the authors note or the process of device insertion or removal destroys precancerous lesions, or that the device induces chronic mucosal inflammation and a long lasting immune response, thereby reducing the likelihood of HPV progression.


Contact: Dani Arbs
IDIBELL-Bellvitge Biomedical Research Institute

Related medicine news :

1. Fish oil reduces effectiveness of chemotherapy
2. Using powder-free latex gloves reduces latex allergy rate in health care workers
3. Common class of pain drugs reduces severity of postpartum breast cancers
4. Music reduces anxiety in cancer patients
5. Hormone reduces risk of heart failure from chemotherapy
6. Yoga boosts stress-busting hormone, reduces pain: York U study
7. Omega-3 reduces anxiety and inflammation in healthy students
8. Wayne State University researcher argues that sex reduces genetic variation
9. Copper reduces infection risk by more than 40 percent
10. BUSM researchers find herbal medicine treatment reduces inflammation in allergen-induced asthma
11. Lung cancer screening trial shows screening with CT scans reduces lung cancer deaths
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... Doulagivers is O'Brien's licensed ... and End of Life Doula Training. A Doulagiver is a non-medical person ... emotionally. Based on her #1 International bestselling book Creating Positive Passings & ...
(Date:10/12/2015)... ... October 13, 2015 , ... North American Tool Corporation ... the 2015 IBC National Meeting in Rosemont, IL on October 4th. ... and standards of excellence that customers have come to expect from members of IBC’s ...
(Date:10/12/2015)... CA (PRWEB) , ... October 12, 2015 , ... ... on August 19, 2015, high school aged female athletes, particularly in the ... potentially sidelining repetitive motion and mechanical overuse injuries than male peers in the ...
(Date:10/12/2015)... ... October 12, 2015 , ... ... hypnosis by individuals who lack professional education and clinical training in a health ... for a variety of purposes such as: losing weight, managing pain, or stopping ...
(Date:10/12/2015)... ... ... The Horizon Foundation for New Jersey has awarded $846,600 in grants to ... quality of life in the Garden State. The grants, representing the second round of ... charitable arm of Horizon Blue Cross Blue Shield of New Jersey, the Horizon Foundation ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... 2015 About epilepsy --> ... of brain disorders manifested by benign to severe, disabling, ... from brain malformations and tumors to meningitis, high-risk pregnancies, ... the disease is unidentified, as is witnessed in the ... An imbalance between the inhibitory and excitatory signals of ...
(Date:10/12/2015)... Elbit Imaging Ltd. ("EI" or the ... board of directors approved a program to repurchase up to ... H Notes and Series I Notes, which are traded on ... the Company will have a significant preference to the purchase ... to time in the open market on the Tel Aviv ...
(Date:10/12/2015)... 2015 A new computer program that analyzes ... whether they will develop effective language skills within two ... in the journal Brain and Behavior . ... the journal,s Oct. 12 online edition, researchers at Cincinnati ... how specific regions of the brain respond to auditory ...
Breaking Medicine Technology: