Navigation Links
IUD Might Ease Heavy Menstrual Bleeding, Study Suggests
Date:1/9/2013

By Serena Gordon
HealthDay Reporter

WEDNESDAY, Jan. 9 (HealthDay News) -- Women with heavy menstrual bleeding may find some relief using an intrauterine device, or IUD, containing the hormone levonorgestrel, according to new research.

British researchers found that the treated IUD was more effective at reducing the effects of heavy menstrual bleeding (also called menorrhagia) on quality of life compared to other treatments. Normally used for contraception, the intrauterine system is sold under the brand name Mirena.

"If women suffer with heavy periods and do not want to get pregnant -- as the levonorgestrel intrauterine system is a contraceptive -- then having the levonorgestrel intrauterine system is a very good first-line treatment option that does not require taking regular, daily oral medications," said the study's lead author, Dr. Janesh Gupta, professor of obstetrics and gynecology at the University of Birmingham and Birmingham Women's Hospital in England.

For women who do want to get pregnant, Gupta said, taking the blood-clotting drug tranexamic acid during periods is an alternate method of treating heavy periods.

Results of the study, which was funded by the United Kingdom's National Institute of Health Research, appear in the Jan. 10 issue of the New England Journal of Medicine.

Heavy menstrual bleeding is a significant problem for many women. About 20 percent of gynecologist office visits in the United States and the United Kingdom are because of heavy bleeding. There are several nonhormonal and hormonal treatment options available to reduce blood loss.

The current study compared the use of traditional medical options -- tranexamic acid pills, mefenamic acid (Ponstel), combined estrogen-progestogen and progesterone alone -- to the use of the levonorgestrel intrauterine system.

The researchers randomly assigned nearly 600 women with heavy menstrual bleeding to receive either the IUD or standard medical care. They assessed improvement using a patient-reported score on a scale designed to measure severity of symptoms. The scale goes from 0 to 100, with lower scores indicating more severe symptoms. The researchers also asked about quality of life and sexual activity, and noted whether a woman needed surgery for heavy periods.

Women in the IUD group reported much greater improvement -- 32.7 points on the symptom scale versus 21.4 points in the standard treatment group. They also reported greater improvements in quality of life.

There was no difference in the rates of surgery or sexual activity between the two groups.

More women were still using the intrauterine system after two years than were still taking standard medical treatments -- 64 percent compared to 38 percent.

Gupta said the main reason she believes the IUD group was more successful at reducing symptoms is that there is "100 percent compliance with treatment as there is a continuous drug treatment effect." Women taking medications may forget to take them sometimes.

Serious side effects were similar between the groups. Gupta said the main side effect from the intrauterine system is irregular periods for up to six months.

Another expert said the findings show promise for women bothered by heavy bleeding.

"This study really adds to the evidence that shows how useful this intrauterine system is for heavy menstrual bleeding," said Dr. Eve Espey, professor of obstetrics and gynecology at the University of New Mexico School of Medicine in Albuquerque.

Getting an intrauterine system generally just requires one office visit, Espey said. Insertion of the device may be mildly uncomfortable for some women, she said.

For women who may be hesitant to use an IUD because of pelvic infections linked to an early version called the Dalkon Shield, Gupta said that as long as women are screened for sexually transmitted diseases before getting an intrauterine system, the risk of infection is low.

Espey agreed. "Today's intrauterine systems have a great side-effect profile," she said. "They also have a high continuation and a high satisfaction rate."

More information

Learn more about intrauterine devices from the Association of Reproductive Healthcare Professionals.

SOURCES: Janesh Gupta, M.D., professor, obstetrics and gynecology, University of Birmingham and Birmingham Women's Hospital, England; Eve Espey, M.D., M.P.H., professor, obstetrics and gynecology, University of New Mexico School of Medicine, Albuquerque, N.M.; Jan. 10, 2013, New England Journal of Medicine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Stool Test Might Aid in Early Detection of Colon Cancer
2. Depo-Provera Birth Control Might Raise Breast Cancer Risk
3. Brain Falters Near End of Life, but Games, Puzzles Might Slow Decline
4. Infection Might Raise Blood Clot Risk for Older Adults: Study
5. Anxiety Might Help People Sniff Out Threats
6. Lung Cancer Screening Might Pay Off, Analysis Shows
7. Mobile Stroke Units Might Trim Time to Treatment
8. Common Plastics Chemical Might Boost Diabetes Risk
9. Media Multitasking Might Have Mental Upside
10. Brain Surgery Might Ease Tough-to-Treat OCD
11. More Smog Might Mean More Hospitalizations
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
IUD Might Ease Heavy Menstrual Bleeding, Study Suggests
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... National recruitment firm ... life sciences executive with extensive sequencing and genomics experience, as Vice President of North ... Ms. Hill will be responsible for leading the sales team in the commercialization of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
Breaking Medicine Technology: