Navigation Links
IMRT improves outcomes in patients with extranodal lymphoma of the head and neck
Date:8/14/2011

PHILADELPHIA (August 15, 2011)Lymphoma is a cancer that affects organs of the immune system, including the lymph nodes. In a subtype of the disease called extranodal lymphoma, tumors arise in non-lymphoid organs, such as the tongue and tonsils. Patients with extranodal lymphoma of the head and neck often undergo radiation therapy, but this treatment frequently damages the salivary glands and causes dry mouth, which can lead to problems with eating, speaking and swallowing.

An advanced radiation therapy technique called Intensity Modulated Radiation Therapy (IMRT) produces no major side effects and a high response rate in patients with extranodal lymphoma of the head and neck, according to new research from Fox Chase Cancer Center. Aruna Turaka, M.D., a radiation oncologist at Fox Chase, presented the findings at the 2011 Pan Pacific Lymphoma Conference on Monday, August 15.

IMRT involves using a computer to deliver radiation doses with the optimal intensity and pattern so that the radiation beam conforms to the three-dimensional shape of the tumor and spares healthy surrounding tissue. The procedure is commonly used to treat head and neck cancer because it provides better local control rates and causes fewer side effects, such as dry mouth com pared with standard conventional radiation therapy techniques. But whether IMRT is the best radiation therapy for patients with extranodal lymphoma of the head and neck had not been previously investigated.

"IMRT is a promising technique that should be used to treat extranodal lymphoma, in addition to chemotherapy," Turaka says. "Radiation acts as a form of local treatment that prevents loco- regional relapses, and chemotherapy helps to prevent systemic relapses."

In the new study, Turaka and her colleagues identified five patients with extranodal lymphoma of the head and neck who were treated with IMRT at Fox Chase between 2007 and 2010. Four of these individuals also received chemotherapy. All of the patients had stage IEA disease, indicating that the cancer was located in a single region and there were no systemic symptoms, such as fever, drenching night sweats, and weight loss.

After treatment, the majority of patients showed improved outcomes and only minor symptoms. There were no occurrences of severe dry mouth, no relapses in the head or neck, and no evidence of tissue abnormalities appearing on positron emission tomography scans (PET) of these regions. Only one individual experienced a systemic relapse, and four people survived during the follow-up period. The findings show that IMRT helps to control local tumors while keeping side effects at a minimum.

In follow-up studies, Turaka will examine the effectiveness and side effects of IMRT, in comparison with conventional radiation therapy approaches, in a larger group of patients with extranodal lymphoma affecting various sites in the body.

"Though these types of lymphomas are rare, it's important to treat them using advanced techniques, such as IMRT, to achieve better results and give good symptom relief to patients," Turaka says.


'/>"/>

Contact: Diana Quattrone
Diana.Quattrone@fccc.edu
215-728-7784
Fox Chase Cancer Center
Source:Eurekalert

Related medicine news :

1. Pharmacist-directed anticoagulation service improves care coordination
2. Deep Brain Stimulation Improves Parkinsons Symptoms Long-Term
3. Weight loss improves sexual health of overweight men with diabetes
4. Hospice improves care for dementia patients and their families
5. Elimination of national kidney allocation policy improves minority access to transplants
6. Drug improves brain function in condition that leads to Alzheimers
7. For Some Prostate Cancer Patients, Combo Treatment Improves Survival
8. Arthroscopic treatment of common hip problem improves range of motion
9. Medicaid Coverage Substantially Improves Access to Care: Study
10. Endosonography followed by surgical staging improves quality of life, according to ASTER study
11. Medicaid increases use of health care, decreases financial strain, improves health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2016)... ... ... a challenge for all of us, but there are things we can do to improve the ... is showing more and more that there are simple, yet important steps that can be taken ... priorities Dr. Kohli’s recommends for her patients include;, , exercise , ...
(Date:4/29/2016)... ... 2016 , ... World Patent Marketing , a vertically ... automotive invention that improves the storage features of a pick up truck. , ... Cooper, CEO and Creative Director of World Patent Marketing. "Over the next five ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... In an ... mother and divorcee, shares her enthusiasm for Botox and lip injections, which she underwent ... famous youth oriented Coachella Valley Music and Arts Festival. The article explains that Ms. ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... Accreditation Council for Graduate Medical Education (ACGME) that it has received accreditation for ... first accreditation of three residency programs that Memorial is currently pursuing, including Pediatrics ...
(Date:4/29/2016)... Beach, Calif. (PRWEB) , ... April 29, 2016 , ... ... us. An effective way to confront and deal with these stressors is to adopt ... bad to be good for you. Risa Groux, a certified Holistic Nutritionist and the ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016   Zillion Group today announced ... platform, which specializes in live video consultation. Turning ... products, Zillion enables companies to realize the true ... take control of their health. ... including one-to-one, group and webcast scheduled or on-demand ...
(Date:4/27/2016)... DUBLIN , April 27, 2016 /PRNewswire/ ... the addition of the  "Global Anesthesia Disposables ... (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ) ,The global ... at a CAGR of 4.03% during the ... are a major threat to patients, safety. ...
(Date:4/27/2016)... 2016 At the Sachs CEO ... a Phase 2 clinical study of its lead drug ... cochlear implantation (CI) surgery. This large, placebo-controlled, double-blind, phase ... Germany and France . ... the time of surgery. "Despite advances in cochlear implant ...
Breaking Medicine Technology: