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IMPAKT Breast Cancer Conference: Oral presentation abstracts online
Date:5/7/2014

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"It is almost unethical that we continue to treat women with metastatic breast cancer when we have so little knowledge of their disease. We now have powerful technologies for investigating the molecular landscape of tumours, and we have an obligation to women to establish AURORA as a large translational research effort that can hopefully lead to more effective treatments in the future." M. Piccart, Chair of BIG and Director of the Medicine Department of the Institut Jules Bordet, Brussels, Belgium

The AURORA trial will be presented during the session
Saturday, 10 May 2014, 10:45-12:35, Gold Hall

Genomics and the importance of translational research to facilitate the implementation of new discoveries into clinical practice

  • Abstract 13O - Evolutionary patterns of microRNA expression through the course of disease and therapy in recurrent breast cancer. M. Dadiani
  • Abstract 20O - Analysis of molecular scores for the prediction of distant recurrence according to body mass index and age at baseline. I. Sestak
  • Abstract 21O - A novel methylation signature that reflects intratumoral lymphocyte infiltration in breast cancer and predicts for response to anthracycline treatment. J. Jeschke

Patients with estrogen-receptor (ER) positive breast cancer receive hormonal treatments after surgery, but sometimes chemotherapy is also needed. The Multidisciplinary Application of Genomics in Clinical Practice (MAGIC) survey investigated on the criteria used to decide about chemotherapy in this patient population. Results show that criteria vary significantly across Europe.

"Data from the MAGIC survey reveal that 55% of responding physicians have adopted genomic tests in their practice but adoption varies strongly across countries. Of those physicians who have not used them, the vast majority indicate that they would like to use genomic tests in clinical practice but report lack of reimburse
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Contact: IMPAKT Press Office
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

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