Navigation Links
IMPACT results show potential cancer treatment
Date:4/19/2010

Dr. Neal Shore (GB) presented for the first time in Europe the updated results of the study "Sipuleucel-T Active Cellular Immunotherapy for Metastatic, Castration-Resistant Prostate Cancer: results from the IMPACT trial," during the second plenary session of the 25th Anniversary EAU Congress in Barcelona.

"This study shows a potential new treatment paradigm in oncology and is the first active immunotherapy to demonstrate improvement in overall survival (OS) for metastatic CRPC (castrate-resistant prostate cancer)," said Shore

Shore said the effect was upheld with longer follow-up and that the majority of the most common adverse events occurred within one day of infusion, were mild and moderate in severity ( < Grade 2) and resolved within one to two days.

"Response rate and time to progression may not be appropriate endpoints in therapeutic vaccine trials," Shore said, adding that the use of immune therapy earlier in the natural history of the disease requires further study.

Sipuleucel-T is an investigational autologous active cellular immunotherapy for treatment of prostate cancer. The randomised, double-blind, placebo controlled phase III trial in CRPC showed a significant increase in OS. Adverse events reported more commonly in the sipuleucel-T than the placebo arm included chills, pyrexia, headache, influenza- like illness, myalgia, hypertension, hyperhidrosis and groin pain.

Other findings indicate that prognostic factors were well-balanced with the median predicted OS of patients in the sipuleucel-T and placebo arms were 20.3 and 21.2 months, respectively, using the Halabi model (2003).


'/>"/>

Contact: Lindy Brouwer
l.brouwer@uroweb.org
European Association of Urology
Source:Eurekalert

Page: 1

Related medicine news :

1. Aleres Dr. Michael Taitel Presents Compelling Evidence at IBI/NBCH Health & Productivity Forum that Wellness Programs Positively Impact Health & Productivity
2. Lung Cancer: Large Impact, Little Funding
3. Study Reveals Impact Of Health Insurance On Hispanics' Attitudes Towards Healthcare Providers
4. The Net Impact is Proud to Announce Partnership with the Karla Smith Foundation
5. Landrieu, Lincoln, Stabenow, Small Business Owners Discuss Positive Impact of Health Reform on Small Businesses
6. Vaccination, antivirals and social distancing may blunt impact of H1N1 influenza
7. Major impacts of climate change expected on mental health
8. Outpatient Palliative Care Reduces Hospitalizations, Which Impact Costs, While Improving Quality of Life for Seniors and Family Caregivers - New Study in American Journal of Managed Care
9. TrekDesk: A Potentially Positive Impact on Diabetes & Obesity
10. 18th Annual Texas Autism Conference Returns To Corpus Christi, Makes Nearly $300,000 Economic Impact
11. China rapidly catching up in research impact
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... (PRWEB) , ... August 16, 2017 , ... Melbourne’s reign ... by the prestigious Economist Intelligence Unit’s (EIU) annual Liveability Index. , The Index surveys ... Since the index began in 2006, Melbourne has consistently come in the top three ...
(Date:8/16/2017)... ... August 16, 2017 , ... Richard Strawn’s new book ... time of a cancer diagnosis, surgery and recovery, the Psalms provided encouragement and ... ways God shows love to those who are sick., Surgical Psalms contains 36 ...
(Date:8/16/2017)... ... August 16, 2017 , ... Kaviva , a health ... the healthcare market, with Los Angeles-based AIDS Healthcare Foundation ( AHF ), to ... AHF cares for nearly 800,000 individuals worldwide and is the largest HIV/AIDS organization ...
(Date:8/16/2017)... Lewisville, TX (PRWEB) , ... August 16, 2017 , ... ... in the United States, named Dr. Douglas J. Harrison, as the new Medical Director ... will be the new facility Medical Director of our Sienna Plantation location,” said Dr. ...
(Date:8/16/2017)... Ohio (PRWEB) , ... August 16, 2017 , ... ... are an annual all-encompassing awards program which recognizes organizations that demonstrate the core ... set of comprehensive award categories. , “As a global company, we are expanding ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)...  Life Flight Network and PeaceHealth Oregon Network announced they ... and operational efficiency for patients at hospitals in ... Cottage Grove , and Florence, Oregon ... Flight Network work collaboratively to move patients who require the ... time sensitive emergency exists. ...
(Date:8/1/2017)...   CerSci Therapeutics , a non-opioid drug development ... has received notice from the National Institute on Drug ... that it has been awarded a Direct-to-Phase II Small ... 2017 with an additional $1,000,000 to follow in 2018. ... of their lead non-opioid drug candidate CT-044 to the ...
(Date:7/31/2017)... 2017 Three Tru-D SmartUVC robots have arrived at ... . Tru-D, short for "Total Room Ultraviolet Disinfection," is a 5-foot-5 ... environmental services (ES) professional cleans the area with traditional cleaning protocols. ... Tru-D fights germs at ... "Although the BAACH has a very low ...
Breaking Medicine Technology: