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IDM Pharma Announces Data Presentation From Mifamurtide (L-MTP-PE) Compassionate Use Program
Date:11/2/2007

IRVINE, Calif., Nov. 2 /PRNewswire-FirstCall/ -- IDM Pharma, Inc. (Nasdaq: IDMI) today announced the presentation of data from a compassionate use program evaluating mifamurtide (L-MTP-PE) in patients with lung metastases as a result of the progression of osteosarcoma, a rare and often fatal bone tumor that typically affects children and young adults. The data show that L-MTP-PE in combination with other therapies is safe, well-tolerated and exhibited signs of disease control.

"These results are encouraging as there is a significant unmet treatment need for patients with osteosarcoma," said Dr. Peter Anderson, professor of pediatrics, The University of Texas M.D. Anderson Cancer Center in Houston. "The safety and tolerability as well as signal of disease control associated with L-MTP-PE treatment in combination with other agents is promising as we continue to investigate therapies to control lung metastases as a result of the progression of osteosarcoma."

The data were presented during a poster presentation at the 39th Congress of International Society of Pediatric Oncology (SIOP) today in Mumbai, India.

Study design and findings

Thirteen high-risk osteosarcoma patients have been treated in the compassionate use program to date. Patients in the program had documented diagnosis of high grade osteosarcoma with relapsed or recurrent disease, locally or metastatic, with resectable or not completely resectable disease, or who are unable to complete recommended chemotherapy due to toxicity.

L-MTP-PE (2 mg/m2 IV over 1 hour) was administered twice a week for 12 weeks followed by once a week for 24 weeks in combination with aerosol recombinant granulocyte monocyte colony stimulating factor (GM-CS
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SOURCE IDM Pharma, Inc.
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