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ID physicians call for 10 new antibiotics by 2020
Date:3/16/2010

Arlington, Va. As the deaths and suffering caused by antibiotic-resistant bacterial infections continue to rise around the world, the Infectious Diseases Society of America (IDSA) is urging a global commitment to develop 10 new antibiotics by 2020, known as the 10 x '20 initiative, to address this public health crisis and safeguard patients' health.

The plea for U.S. and global action comes in a statementpublished in the April 15 issue of Clinical Infectious Diseases and available online this weekthat outlines the dangers and recommends how to address what the World Health Organization (WHO) has identified as one of the three greatest threats to human health. The IDSA statement is available at www.journals.uchicago.edu/doi/full/10.1086/652237. Recent studies have shown there are few antibiotics in the development pipeline that would offer benefits over existing drugs. The existing drugs we do have available are in danger of becoming ineffective as bacteria increasingly develop resistance.

"Prior generations gave us the gift of antibiotics," said David Gilbert, MD, FIDSA, chair of IDSA's Antimicrobial Availability Task Force, which authored the IDSA statement. "Today, we have a moral obligation to ensure this global treasure is available for our children and future generations."

Solving the antibiotic pipeline problem will require the engagement of global political, scientific, medical, industry and policy leaders to determine the right combination of incentives necessary to drive innovation in this diminishing segment of the pharmaceutical market. The ultimate goal must be the creation of a sustainable research and development enterprise that can deliver new antibiotics on an on-going basis. Resistant organisms will continue to develop in perpetuity, so we must have a plan in place to replenish our arsenal of drugs into the foreseeable future.

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Contact: John Heys
jheys@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

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