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IBM Research Aims to Build Nanoscale DNA Sequencer to Help Drive Down Cost of Personalized Genetic Analysis
Date:10/6/2009

YORKTOWN HEIGHTS, N.Y., Oct. 6 /PRNewswire-FirstCall/ -- In an effort to build a nanoscale DNA sequencer, IBM (NYSE: IBM) scientists are drilling nano-sized holes in computer-like chips and passing DNA strands through them in order to read the information contained within their genetic code.

View video: http://www.youtube.com/watch?v=pKi30ai35mU

View animation: http://www.youtube.com/watch?v=wvclP3GySUY

For an ongoing conversation on this research project, visit the Smarter Planet blog: http://asmarterplanet.com/blog/2009/10/dna-transistor.html

(Photo: http://www.newscom.com/cgi-bin/prnh/20091006/NY87582 )

(Logo: http://www.newscom.com/cgi-bin/prnh/20090416/IBMLOGO )

This advanced research effort to demonstrate a silicon-based "DNA Transistor" could help pave the way to read human DNA easily and quickly, generating advancements in health condition diagnosis and treatment. The challenge in the effort is to slow and control the motion of the DNA through the hole so the reader can accurately decode what is in the DNA. If successful, the project could improve throughput and reduce cost to achieve the vision of personalized genome analysis at a cost of $100 to $1,000. In comparison, the first sequencing ever done by the Human Genome Project (HGP) cost nearly $3 billion.

Having access to an individual's personal genetic code could advance personalized medicine by using genomic and molecular data to facilitate the discovery and clinical testing of new products, and help
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SOURCE IBM
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