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IASLC: Adjunctive use of 3-D imaging system increases utility of CT lung cancer screening
Date:7/3/2011

ated with potential malignancy. The analysis yields a score that indicates whether or not cancer cells are present in the sample. The Cell-CT system produces strikingly clear and comprehensive 3D images of the cells, enabling extremely accurate classifications. VisionGate researchers estimate that LuCED will be able to achieve specificity of 99% and sensitivity of 75% in actual use.

"The dramatic results of the NLST study provide us with a valuable initial indication for our LuCED test," commented Scarlett Spring, president of VisionGate. "By combining the high accuracy and cost effectiveness of our non-invasive LuCED diagnostic with the proven ability of CT screening to reduce lung cancer deaths, we hope to make mass screening feasible and affordable. We believe that we have developed an efficient clinical and regulatory strategy for our proposed use of LuCED to manage the false positive results from CT screening, and we look forward to advancing this program in the coming months."

Prior to the development of LuCED, a number of studies had confirmed that analyzing cells in sputum could potentially be useful in the early detection of lung cancer, showing that 85% of sputum samples from individuals with lung cancer (the samples were taken over three days and pooled) actually contained cancer cells. However, the typically poor sensitivity of raw sputum analysis and the labor intensive nature of the process made it impracticable for widespread use in lung cancer screening. The Cell-CT platform's 3D technology, along with its advanced automated 3D image analysis algorithms, for the first time make a cell-based sputum analysis approach both logistically feasible and cost effective.


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Contact: Barbara Lindheim
blindheim@biocompartners.com
917-355-9234
BioCom Partners
Source:Eurekalert

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