Navigation Links
Hyperventilation may trigger febrile seizures in children

New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity. Febrile seizures were not observed in susceptible children with fevers brought on by gastroenteritis, suggesting that low blood pH levels (acidosis) may have a protective effect. Full findings now appear in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE).

Febrile seizures are the most common type of convulsive disorder in children, affecting nearly 1 out of every 25 children and typically occurring between the ages of 6 months and 5 years, according to the National Institute of Neurological Disorders and Stroke (NINDS). Previous studies have suggested that a combination of genetic and environmental factors cause febrile seizures which have an incidence of up to 8% depending on geographical region and culture.

To further understand the functional changes associated with febrile seizures, a team of investigators, led by Dr. Sebastian Schuchmann, at the Charit-Universittsmedizin Berlin in Germany and the University of Helsinki in Finland enrolled and analysed 433 children with similar fever levels who were admitted to hospital for febrile seizure (n=213) or gastroenteritis (n=220). All pediatric patients had their blood pH and carbon dioxide levels measured upon admission.

Researchers found respiratory alkalosis in children with febrile seizures and metabolic acidosis in pediatric patients admitted for gastroenteritis. Febrile seizures did not occur in children with gastroenteritis, except in a subgroup of 15 patients who had an alkaline blood pH level. Additionally, 8 patients were admitted on separate occasions for febrile seizures and gastroenteritis; blood pH was elevated when the child was admitted with febrile seizure, but a more acidotic pH was found when the child presented with gastroenteritis.

"Our findings reveal that febrile seizures are associated with respiratory alkalosis and unrelated to the severity of the underlying infection or fever level," concluded Dr. Schuchmann. "Further investigation of methods that control the body's acid-base status may lead to the development of novel therapies for treating febrile seizures." Based on the study results, the authors suggest an application of 5% carbon dioxide in the breathing air as a possible treatment for febrile seizures.


Contact: Dawn Peters

Related medicine news :

1. Climate Change May Trigger More Asthma Emergencies
2. UCI researchers find link between environment and genetics in triggering MS
3. Why does flu trigger asthma?
4. Can Platelet Transfusions Trigger Severe Reaction in Those With Peanut Allergies?
5. Rapid growth may be appropriate trigger for treatment in patients with renal masses
6. Secondhand Smoke May Trigger Nicotine Craving
7. Seeing Others Scratch Can Trigger Your Own Itch
8. NFL Upsets Could Trigger Domestic Violence
9. Nottingham scientists identify trigger in cat allergy
10. Coffee, Sex, Smog Can All Trigger Heart Attack, Study Finds
11. Study reveals how fusion protein triggers cancer
Post Your Comments:
(Date:12/1/2015)... N.C. (PRWEB) , ... December 01, 2015 , ... The ... to drive awareness and funds for Multiple System Atrophy (MSA) research, timed today to ... Atrophy takes many things from patients including their ability to work and be productive, ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... Royal River ... a new study that found post-menopausal women who took the nutritional supplement creatine, along ... women who trained but did not take creatine. , The report is part of ...
(Date:12/1/2015)... ... December 01, 2015 , ... Baptist Medical Center Jacksonville has ... the only hospital in the region providing what is known as the world’s ... patients were revealed recently at a medical conference and published in The New ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... identification tests to continue the expansion of the company’s growing product line of ... for Chinook (Oncorhynchus tshawytscha) and Sockeye (Oncorhynchus nerka) – allow InstantLabs to offer ...
(Date:12/1/2015)... ... December 01, 2015 , ... Diabetic foot wounds ... Podiatrists are well aware that psychology-based patient non-compliance (disobedience of a health care ... to diseases of the diabetic foot. The American Board of Multiple Specialties ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... --> --> ... Acid Labeling Market by Product (Reagents & Kits, Services), ... Vitro Transcription, Reverse Transcription, End Labeling), by Region - ... market is expected to reach USD 1,925.7 Million by ... a CAGR of 8.65%. Browse 77 market ...
(Date:12/1/2015)... 1, 2015 Building on its 25-year ... Johnson (NYSE: JNJ ) today announced four ... to significantly reduce the burden of HIV incidence, ... percent of new HIV infections among adolescents in ... Day, these new initiatives include collaborations with the ...
(Date:12/1/2015)... DUBLIN , Dec. 01, 2015 ... ) has announced the addition of ... Testing Market: Campylobacter, Cryptosporidium, E. Coli, ... Yersinia" report to their offering. ... announced the addition of the ...
Breaking Medicine Technology: