Navigation Links
Hypertension during pregnancy increases risk of end-stage renal disease
Date:1/22/2013

Women with hypertensive disorders in pregnancy are at higher risk of chronic kidney disease and end-stage renal disease compared with women without the disorders, according to a study in CMAJ (Canadian Medical Association Journal).

"We found that women with hypertensive disorders during pregnancy were at higher risk of end-stage renal disease than women without complicated pregnancies," writes Dr. I-Kuan Wang, Division of Nephrology, China Medical University Hospital, Taichung, Taiwan, with coauthors.

Hypertensive disorders such as gestational hypertension and preeclampsia in pregnancy can have a major impact on the health of the mother and baby and are risk factors for death. An estimated 5% to 10% of pregnancies are affected by hypertensive disorders. Kidney function can be affected.

Researchers looked at data on 26 651 women in Taiwan with hypertensive disorders in their first pregnancy to determine whether there was an increased risk of end-stage renal disease compared with a group of 213 397 women without the disorders. The women were 19 to 40 years old and did not have a history of hypertension, diabetes or kidney disease.

Taiwan has one of the highest rates of end-stage renal disease in the world.

The incidence of chronic kidney disease was almost 11-fold higher in the group with hypertensive disorders in pregnancy compared with the women without the disorders. End-stage renal disease was 14-fold higher in the cohort with hypertensive disorders. The risk for women with preeclampsia was higher than for those with only gestational hypertension.

"We found an increased risk of subsequent end-stage renal disease among Taiwanese women who had experienced hypertensive disorders during pregnancy, including preeclampsia or eclampsia and gestational hypertension," write the authors. "We also found that women with preeclampsia or eclampsia were at higher risk of end-stage renal disease than those who had gestational hypertension only."

There is little data on the link between hypertensive disorders during pregnancy and the risk of end-stage renal disease. This study is consistent with a Norwegian study that found a similar link between these disorders and later kidney disease.

"Close surveillance for microalbuminuria, blood pressure and diabetes should be considered for women with a history of hypertensive disorders during pregnancy. Preventive strategies, such as pharmacologic or lifestyle interventions, should also be considered for women at high risk of end-stage renal disease," conclude the authors.

"This study by Wang and colleagues is timely because it shows the importance of hypertension during pregnancy as a marker for future chronic kidney disease, cardiovascular disease and diabetes," write Dr. Julia Spaan from Maastricht University Medical Center, the Netherlands, and Prof. Dr. Mark Brown from the University of New South Wales, Australia, in a related commentary (pre-embargo link only) "It also highlights one of the current pitfalls of clinical practice: although these women have great attention paid to their high blood pressure during pregnancy, there is no structured follow-up of blood pressure or cardiovascular and renal risk factors after pregnancy. Better surveillance after pregnancy should help prevent not only chronic kidney disease but also cardiovascular disease.


'/>"/>

Contact: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Source:Eurekalert

Related medicine news :

1. URMC clinical trial tests new regimen for hypertension
2. Pittsburgh Cardiologist Named Physician of the Year by Pulmonary Hypertension Association
3. UGA study shows why hypertension increases damage to eyes of diabetic patients
4. Blacks More Prone to Hypertension After Certain Strokes
5. Renal denervation treats resistant hypertension in real world patient populations
6. Renal sympathetic denervation improves physical and mental health in resistant hypertension
7. Healthy lifestyle reduces the risk of hypertension by two thirds
8. Oxford University Press acquires American Journal of Hypertension
9. Kidney stenting lowers blood pressure in patients with severe hypertension
10. NY-Presbyterian Hospital announces participation in trial for hard-to-treat hypertension
11. Treating Kidneys With Radio Waves May Ease Tough-to-Control Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join ... wage raise to $12 an hour by 2020 and then adjusting it yearly to increase ... of the minimum wage, assure the wage floor does not erode again, and make future ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the placement ... Vice President of North American Capital Sales at HTG Molecular . ... in the commercialization of the HTG EdgeSeq system and associated reagents in North America. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Today, ... stem (iPS) cells and other difficult to transfect cells, announces its launch of ... PluriQ™ G9™ Gene Editing System is a complete system for culturing and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
(Date:6/23/2016)... Ill. and INDIANAPOLIS , ... students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is ... 2016 scholarship winners, announced today online at www.diabetesscholars.org ... let type 1 diabetes stand in the way of ... has supported the Foundation,s scholarship program since 2012, and ...
Breaking Medicine Technology: