Navigation Links
Hypertension during pregnancy increases risk of end-stage renal disease
Date:1/22/2013

Women with hypertensive disorders in pregnancy are at higher risk of chronic kidney disease and end-stage renal disease compared with women without the disorders, according to a study in CMAJ (Canadian Medical Association Journal).

"We found that women with hypertensive disorders during pregnancy were at higher risk of end-stage renal disease than women without complicated pregnancies," writes Dr. I-Kuan Wang, Division of Nephrology, China Medical University Hospital, Taichung, Taiwan, with coauthors.

Hypertensive disorders such as gestational hypertension and preeclampsia in pregnancy can have a major impact on the health of the mother and baby and are risk factors for death. An estimated 5% to 10% of pregnancies are affected by hypertensive disorders. Kidney function can be affected.

Researchers looked at data on 26 651 women in Taiwan with hypertensive disorders in their first pregnancy to determine whether there was an increased risk of end-stage renal disease compared with a group of 213 397 women without the disorders. The women were 19 to 40 years old and did not have a history of hypertension, diabetes or kidney disease.

Taiwan has one of the highest rates of end-stage renal disease in the world.

The incidence of chronic kidney disease was almost 11-fold higher in the group with hypertensive disorders in pregnancy compared with the women without the disorders. End-stage renal disease was 14-fold higher in the cohort with hypertensive disorders. The risk for women with preeclampsia was higher than for those with only gestational hypertension.

"We found an increased risk of subsequent end-stage renal disease among Taiwanese women who had experienced hypertensive disorders during pregnancy, including preeclampsia or eclampsia and gestational hypertension," write the authors. "We also found that women with preeclampsia or eclampsia were at higher risk of end-stage renal disease than those who had gestational hypertension only."

There is little data on the link between hypertensive disorders during pregnancy and the risk of end-stage renal disease. This study is consistent with a Norwegian study that found a similar link between these disorders and later kidney disease.

"Close surveillance for microalbuminuria, blood pressure and diabetes should be considered for women with a history of hypertensive disorders during pregnancy. Preventive strategies, such as pharmacologic or lifestyle interventions, should also be considered for women at high risk of end-stage renal disease," conclude the authors.

"This study by Wang and colleagues is timely because it shows the importance of hypertension during pregnancy as a marker for future chronic kidney disease, cardiovascular disease and diabetes," write Dr. Julia Spaan from Maastricht University Medical Center, the Netherlands, and Prof. Dr. Mark Brown from the University of New South Wales, Australia, in a related commentary (pre-embargo link only) "It also highlights one of the current pitfalls of clinical practice: although these women have great attention paid to their high blood pressure during pregnancy, there is no structured follow-up of blood pressure or cardiovascular and renal risk factors after pregnancy. Better surveillance after pregnancy should help prevent not only chronic kidney disease but also cardiovascular disease.


'/>"/>

Contact: Kim Barnhardt
kim.barnhardt@cmaj.ca
613-520-7116 x2224
Canadian Medical Association Journal
Source:Eurekalert

Related medicine news :

1. URMC clinical trial tests new regimen for hypertension
2. Pittsburgh Cardiologist Named Physician of the Year by Pulmonary Hypertension Association
3. UGA study shows why hypertension increases damage to eyes of diabetic patients
4. Blacks More Prone to Hypertension After Certain Strokes
5. Renal denervation treats resistant hypertension in real world patient populations
6. Renal sympathetic denervation improves physical and mental health in resistant hypertension
7. Healthy lifestyle reduces the risk of hypertension by two thirds
8. Oxford University Press acquires American Journal of Hypertension
9. Kidney stenting lowers blood pressure in patients with severe hypertension
10. NY-Presbyterian Hospital announces participation in trial for hard-to-treat hypertension
11. Treating Kidneys With Radio Waves May Ease Tough-to-Control Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... May 26, 2016 , ... Despite last week’s media reports hinting at a ... to wait until March 2017 for an interest rate increase, according to Rajeev Dhawan ... Business. , “The Federal Open Market Committee (FOMC) dot charts are of interest to ...
(Date:5/26/2016)... St. Louis, Missouri (PRWEB) , ... May 26, ... ... optimal cost, quality and clinical outcomes, hosted members and suppliers for its inaugural ... with a focus on their mission of elevating the operational health of America’s ...
(Date:5/26/2016)... ... 26, 2016 , ... The Woodlands at John Knox Village , Florida’s ... care for living and healing, celebrated its grand opening, today. The Woodlands at John ... provided by Empowered Staff. , “This is an incredibly fulfilling time for John Knox ...
(Date:5/26/2016)... N.J. (PRWEB) , ... May 26, 2016 , ... ... delivery technologies and development solutions for drugs, biologics, consumer health and global clinical ... sales office in Korea to support the company’s continued investment and strategic growth ...
(Date:5/26/2016)... ... , ... Memorial Day Weekend marks the unofficial start of summer and the ... make sure your family and vehicle are ready to hit the road this weekend. ... deaths and an additional 50,500 serious injuries from motor vehicle crashes during the three-day ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... , May 25, 2016  Zymo Research Corp. ... their new reference materials that help researchers obtain ... collection to analyses. The rapid growth of the ... researchers to have standard methods to improve the ... Biases inherently exist at every step of the ...
(Date:5/25/2016)... May 25, 2016  Granger Diagnostics today announced immediate ... wounds and infections. This test ensures discovery of ... viruses. The test requires only a simple swab of ... David G. Bostwick , MD, Chief Medical ... wound healing: "We are excited to make available, ...
(Date:5/25/2016)... , May 25, 2016 ... H1 2016"market research report that provides an overview ... comparative analysis at various stages, therapeutics assessment by ... administration (RoA) and molecule type, along with latest ... also reviews key players involved in the therapeutic ...
Breaking Medicine Technology: