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Hypertension Triples Women's Diabetes Risk
Date:10/10/2007

It does so outside of normal diabetes risk factors, such as obesity, study finds

WEDNESDAY, Oct. 10 (HealthDay News) -- Compared to women with optimal blood pressure, those with high blood pressure are up to three times more likely to develop type 2 diabetes, a U.S. study finds.

The link between high blood pressure and diabetes risk was independent of factors known to increase the odds of getting diabetes and cardiovascular disease, said the researchers from Brigham and Women's Hospital, Harvard Medical School and the Harvard School of Public Health.

Reporting in the Oct. 9 European Heart Journal, the team tracked the health of more than 38,000 female health professionals for more than 10 years. At the start of the study, the women (all free of diabetes or cardiovascular disease) were divided into four groups based on their blood pressure: optimal -- below 120 mm/Hg systolic, 75 mm/Hg diastolic; normal -- 120-129 mm/Hg systolic, 75-84 mm/Hg diastolic; high-normal -- 130-139 mm/Hg systolic, 85-89 mm/Hg diastolic; and high blood pressure -- at least 140 mm/Hg systolic, 90 mm/Hg diastolic, and/or a self-reported history of hypertension or treatment for the condition.

After 10 years, 9.4 percent of the women in the high blood pressure group had developed type 2 diabetes, compared with 5.7 percent in the high-normal group, 2.9 percent in the normal group, and 1.4 percent in the optimal group.

After adjusting for a number of factors such as age, smoking, alcohol consumption, body mass index, exercise, and family history of diabetes, the researchers concluded that the women with high blood pressure still had a threefold increased risk of diabetes compared to women with optimal blood pressure.

"We found that obesity was also a strong and independent risk factor for the development of type 2 diabetes. However, statistical analyses showed that the relationship between blood pressure and the onset of type 2 d
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