Navigation Links
Hushed Genes Might Mean Higher Lung Cancer Risk
Date:9/19/2007

The suppression of certain DNA predicts malignancy, study finds

WEDNESDAY, Sept. 19 (HealthDay News) -- If the collective activity of 15 genes that protect against lung cancer is too quiet, it could mean that they're being suppressed -- a situation that may lead to lung malignancy, U.S. researchers warn.

A team at the University of Toledo, in Ohio, say a test for these genes in lung cells collected via bronchoscopy could help identify people genetically at risk for lung cancer.

The researchers analyzed the activity of these 15 genes in 25 people with lung cancer and 24 people without the disease.

By doing so, they were able to correctly identify those with lung cancer 96 percent of the time. The findings were to be presented Tuesday at an American Association for Cancer Research Conference in Atlanta.

The genes included in the analysis encode a protective antioxidant and DNA repair proteins found in lung airway cells.

"Smoking causes about 90 percent of all lung cancer cases, yet only about 10 to 15 percent of heavy smokers will develop lung cancer," lead researcher Dr. James C. Willey, an associate professor of medicine and molecular biology at the University of Toledo's College of Medicine, said in a prepared statement.

"We are looking for new techniques that will allow us to pick out the 10 to 15 percent of individuals at highest risk for lung cancer from the enormous pool of current and former smokers," he said.

The findings from this study justify a larger, prospective study to determine whether this approach is useful in predicting lung cancer in current and former smokers, Willey and his colleagues believe.

More information

The U.S. National Cancer Institute has more about lung cancer risk.



-- Robert Preidt



SOURCE: American Association for Cancer Research Conference, Sept. 18, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
2. Genes for lung disease
3. Genesis of SUPAC
4. Cirrhosis linked to genes
5. Altering genes through calories
6. Predictable genes
7. Genes for Vision discovered
8. Endometriosis coalesced with genes
9. Birth weight may be influenced by genes
10. New breast cancer genes discovered
11. Altitude sickness connected to genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal their media with ... X," said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color ... users can now reveal the media of their split screens with growing colorful ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their ... Eyeglasses . , Millions of individuals in the United States and Canada wear eyeglasses. ... way to both correct vision and make a fashion statement. Even celebrities use glasses ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can ... Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey ... cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... , June 23, 2016  In a startling report released ... failing their residents by lacking a comprehensive, proven plan to eliminate ... a definitive ranking of how states are tackling the worst drug ... only four states – Kentucky , ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
Breaking Medicine Technology: