Navigation Links
Hurts so good -- neural clues to the calming effects of self-harm
Date:8/30/2010

Philadelphia, PA, 30 August 2010 - The notion that cutting or burning oneself could provide relief from emotional distress is difficult to understand for most people, but it is an experience reported commonly among people who compulsively hurt themselves.

Individuals with borderline personality disorder experience intense emotions and often show a deficiency of emotion regulation skills. This group of people also displays high prevalence rates of self-injurious behavior, which may help them to reduce negative emotional states.

Niedtfeld and colleagues studied the effects of emotional stimuli and a thermal stimulus in people either with or without borderline personality disorder. They conducted an imaging study using picture stimuli to induce negative, positive, or neutral affect and thermal stimuli to induce heat pain or warmth perception. The painful heat stimuli were administered at an individually-set temperature threshold for each subject.

In patients with borderline personality disorder, they found evidence of heightened activation of limbic circuitry in response to pictures evocative of positive and negative emotions, consistent with their reported emotion regulation problems. Amygdala activation also correlated with self-reported deficits in emotion regulation. However, the thermal stimuli inhibited the activation of the amygdala in these patients and also in healthy controls, presumably suppressing emotional reactivity.

Dr. John Krystal, Editor of Biological Psychiatry, commented, "These data are consistent with the hypothesis that physically painful stimuli provide some relief from emotional distress for some patients with borderline personality disorder because they paradoxically inhibit brain regions involved in emotion. This process may help them to compensate for deficient emotional regulation mechanisms."

The authors note that these results are in line with previous findings on emotional hyperactivity in borderline personality disorder and suggest that these individuals process pain stimuli differently depending on their arousal status.


'/>"/>

Contact: Chris J. Pfister
c.pfister@elsevier.com
215-239-3266
Elsevier
Source:Eurekalert

Related medicine news :

1. Senate Inaction On Medicare Hurts Seniors, Military and Boomers
2. Using gold nanoparticles to hit cancer where it hurts
3. Neuralstem files FDA application for first chronic spinal cord injury stem cell trial
4. Human neural stem cells restore motor function in mice with chronic spinal cord injury
5. FDA approves first human neural stem cell clinical trial to treat brain tumors
6. Neuralstem updates clinical trial progress
7. Race and empathy matter on neural level
8. Long-Term Type 1 Diabetes Survivors Give Clues to the Disease
9. More Clues To Fibromyalgia Pain
10. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
11. New Clues for Treating Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/18/2017)... Lewisberry, PA (PRWEB) , ... February 17, 2017 , ... ... more about the Stannah Stairlift and other Butler products. Ken was impressed with ... team, and agreed to endorse the product on his show. This endorsement by ...
(Date:2/18/2017)... , ... February 18, 2017 , ... ... Use Pixel Film Studios ’ ProParagraph Fashion Volume 2 for all ... many other applications. Users can pick and choose from hand-crafted trend-setting designs ...
(Date:2/17/2017)... , ... February 17, 2017 , ... ... not kept pace. Enovate Medical has introduced an innovative workstation designed to reduce ... supporting nurses, the Encore Mobile EHR Workstation offers a lightweight, highly mobile, multi-functional ...
(Date:2/17/2017)... Nashville, TN (PRWEB) , ... February 17, 2017 ... ... Services, Inc. (ISTS) brings its educational assistance management solution to the exhibit floor ... Convention Center in Orlando, Fla. , From Feb. 19–23, 2017, more than ...
(Date:2/17/2017)... ... February 17, 2017 , ... Corrective Action & Preventive ... FDAnews Webinar**, Feb. 23, 2017 — 1:30 p.m. – 3:00 p.m. ET, ... and preventive action (PA)? , The methods share techniques and tools but they ...
Breaking Medicine News(10 mins):
(Date:2/18/2017)... 2017 Research and Markets has announced the addition ... their offering. ... provides separate comprehensive analytics for the US, Canada , ... Asia-Pacific , Latin America , and Rest of ... 2022. Also, a six-year historic analysis is provided for these markets. Market ...
(Date:2/17/2017)... Conn. , Feb. 17, 2017 Arvinas ... of drugs based on protein degradation, today announced the ... receptor (AR) PROTAC during a poster session at the ... (ASCO GU) in Orlando, FL. ... to validate our platform and the potential of PROTACs ...
(Date:2/17/2017)... 2017   Risperdal lawsuits involving gynecomastia (male breast ... use of the atypical antipsychotic medication continue to move ... of Common Pleas, where the state,s Risperdal docket has ... a notice posted on the Court,s website , ... March 9, 2017 at 11:00 a.m. (In Re: Risperdal ...
Breaking Medicine Technology: