Navigation Links
Hurts so good -- neural clues to the calming effects of self-harm
Date:8/30/2010

Philadelphia, PA, 30 August 2010 - The notion that cutting or burning oneself could provide relief from emotional distress is difficult to understand for most people, but it is an experience reported commonly among people who compulsively hurt themselves.

Individuals with borderline personality disorder experience intense emotions and often show a deficiency of emotion regulation skills. This group of people also displays high prevalence rates of self-injurious behavior, which may help them to reduce negative emotional states.

Niedtfeld and colleagues studied the effects of emotional stimuli and a thermal stimulus in people either with or without borderline personality disorder. They conducted an imaging study using picture stimuli to induce negative, positive, or neutral affect and thermal stimuli to induce heat pain or warmth perception. The painful heat stimuli were administered at an individually-set temperature threshold for each subject.

In patients with borderline personality disorder, they found evidence of heightened activation of limbic circuitry in response to pictures evocative of positive and negative emotions, consistent with their reported emotion regulation problems. Amygdala activation also correlated with self-reported deficits in emotion regulation. However, the thermal stimuli inhibited the activation of the amygdala in these patients and also in healthy controls, presumably suppressing emotional reactivity.

Dr. John Krystal, Editor of Biological Psychiatry, commented, "These data are consistent with the hypothesis that physically painful stimuli provide some relief from emotional distress for some patients with borderline personality disorder because they paradoxically inhibit brain regions involved in emotion. This process may help them to compensate for deficient emotional regulation mechanisms."

The authors note that these results are in line with previous findings on emotional hyperactivity in borderlin
'/>"/>

Contact: Chris J. Pfister
c.pfister@elsevier.com
215-239-3266
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Senate Inaction On Medicare Hurts Seniors, Military and Boomers
2. Using gold nanoparticles to hit cancer where it hurts
3. Neuralstem files FDA application for first chronic spinal cord injury stem cell trial
4. Human neural stem cells restore motor function in mice with chronic spinal cord injury
5. FDA approves first human neural stem cell clinical trial to treat brain tumors
6. Neuralstem updates clinical trial progress
7. Race and empathy matter on neural level
8. Long-Term Type 1 Diabetes Survivors Give Clues to the Disease
9. More Clues To Fibromyalgia Pain
10. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
11. New Clues for Treating Ulcerative Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015 The second episode of ... different people who share a need to transform their lives. ... of Omaha, NE, struggling to deal with the death of ... basketball player from Kansas City, MO, who went into depression ... Kelli’s amazing transformations will be featured in one episode of ...
(Date:5/27/2015)... Throughout the past few months, Push to Walk ... validity and reliability of the Shaw Gait Assessment in comparison ... Professor in the Department of Physical Therapy at Seton Hall ... Shaw Gait Assessment is a free online tool, where the ... is considered the gold standard in providing information about how ...
(Date:5/27/2015)... Thermage was the first to come out with ... 2007 coinciding with the release of NXT or CPT, the ... Aesthetics was the first practice in New York to debut ... results that had never been achieved before non-surgically. Even ... considered by many as the leading skin tightening device. ...
(Date:5/27/2015)... a reputable source of 2015 NHL Western Conference Finals tickets ... their series against the Anaheim Ducks with the Ducks currently ahead ... tonight at home, this will tie up the series with game ... in Anaheim. , During the regular season, the Ducks finished ... the Pacific Division by 8 points ahead of the second place ...
(Date:5/27/2015)... Ticket Down is a reputable source for 2015 ... been super hot during the 2014-15 NBA season and they delighted ... a final score of 118-88. , For the Cavaliers, ... 2006-2007 when they lost to the San Antonio Spurs. Once ... the Cavaliers making it to the NBA finals increased tenfold. ...
Breaking Medicine News(10 mins):Health News:“Extreme Weight Loss”: Josh and Kelli’s Journeys Begin at the University of Colorado Anschutz Health and Wellness Center 2Health News:“Extreme Weight Loss”: Josh and Kelli’s Journeys Begin at the University of Colorado Anschutz Health and Wellness Center 3Health News:Push to Walk Partners with Seton Hall University for Study 2Health News:Non-Surgical Fat Reduction and Skin Tightening Procedures, Thermage and Exilis, Increase 200% at Precision Aesthetics in New York, April 2015 2Health News:Blackhawks vs. Ducks NHL Western Conference Finals Tickets: Ticket Down Slashes Ticket Prices on Chicago Blackhawks vs. Anaheim Ducks 2015 NHL Western Conference Finals 2Health News:Cavs NBA Finals Tickets: Ticket Down Slashes Ticket Prices on Cleveland Cavaliers 2015 NBA Finals Tickets at Quicken Loans Arena and Offers Valuable Promo Code 2
... Partners is being recognized as one of the top performing California ... year. HealthCare Partners is one of only four California Physicians groups ... , ... (PRWEB) November 11, 2008 -- This is the ...
... Awareness Month--The Apo E Gene Diet--A Solution for ... Other Chronic Illnesses. ,THE APO E GENE DIET ... and Weight Loss" category of National Best Books ... E Gene Diet presents an integrative medicine solution ...
... The 2008 Frost &,Sullivan European Health Ingredient ... in recognition of its pioneering efforts in developing ... "Rather than cure, current medical treatments for ... pain," notes Frost & Sullivan,Research Analyst Kaushik Ghosh. ...
... Nov. 10 KV Pharmaceutical Company,(NYSE: KVa/KVb) announced today ... the Company will be delayed in the filing of,its ... The Company expects to,file a Form 12b-25 Notice of ... November 12, 2008., About KV Pharmaceutical Company, ...
... announced,today that the Company Chief Executive Officer, Steve ... pipeline, at the Rodman &,Renshaw,s 10th Annual Healthcare ... EST at the New York Palace Hotel, 455 ... is a private drug development Company,founded in 1996 ...
... HARRISBURG, Pa., Nov. 10 State agriculture,and health officials ... about important food safety issues made four stops in,northeastern ... Health Secretary Michael,Huff visited the area as part of ... which is a comprehensive plan to address,food safety and ...
Cached Medicine News:Health News:HealthCare Partners Rated A 'Top Performing California Physician Group' By IHA For the Fifth Straight Year 2Health News:HealthCare Partners Rated A 'Top Performing California Physician Group' By IHA For the Fifth Straight Year 3Health News:The Apo E Gene Diet--Preventing, Alzheimer's and Heart Disease, One Patient at a Time 2Health News:The Apo E Gene Diet--Preventing, Alzheimer's and Heart Disease, One Patient at a Time 3Health News:The Apo E Gene Diet--Preventing, Alzheimer's and Heart Disease, One Patient at a Time 4Health News:Frost & Sullivan Honours GELITA for Developing European Health Ingredient of the Year 2Health News:Frost & Sullivan Honours GELITA for Developing European Health Ingredient of the Year 3Health News:KV Pharmaceutical to File Form 12b-25 on November 12, 2008 2Health News:KV Pharmaceutical to File Form 12b-25 on November 12, 2008 3Health News:KV Pharmaceutical to File Form 12b-25 on November 12, 2008 4Health News:Agriculture, Health Officials Address Food Safety Concerns During Northeastern PA Tour 2
(Date:5/27/2015)... 2015  LumiThera Inc., a developmental stage medical ... for ocular disorders and disease, announced today that ... Life Sciences Discovery Fund (LSDF) commercialization grant. ... LSDF matching grants worth $500,000 to provide for ... dry age-related macular degeneration (AMD). ...
(Date:5/27/2015)... Research and Markets( http://www.researchandmarkets.com/research/hxhwtv/asia_pacific ) has announced ... - Growth, Trends And Forecasts (2014 - 2019)" ... Asia Pacific market for Fluoroscopy is ... to 2020 Fluoroscopy is the imaging technology ... the interior of the body. The imaging team consists ...
(Date:5/27/2015)... Donatelli, a senior marketing associate with the animal health division of Eli ... a healthcare setting in Bangkok, Thailand , will be ... need with respect and dignity is the guiding star for me and ... in a LillyPad blog . Donatelli and Lilly colleagues ... Colombia , France , Ukraine ...
Breaking Medicine Technology:LumiThera Receives LSDF Commercialization Grant Award 2Asia Pacific Fluoroscopy Market Trends and Forecasts 2014 - 2019 2Lilly Sends Employees to Serve in Vulnerable Communities around the World 2Lilly Sends Employees to Serve in Vulnerable Communities around the World 3
... CardioFocus, Inc., developer of the HeartLight Endoscopic Ablation ... announced its technology enables a Pulmonary Vein (PV) acute ... PVs remaining persistently isolated after three months.  Additional research ... from AF after a single procedure. ...
... Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ... Day on Thursday, May 12, 2011 from 9:00 a.m. to ... of Lexicon,s senior management team will provide in-depth reviews of ... preclinical programs in the company,s pipeline.  The review of the ...
Cached Medicine Technology:New Studies Support CardioFocus HeartLight™ Endoscopic Ablation System's Notable Treatment Results for Paroxysmal Atrial Fibrillation 2New Studies Support CardioFocus HeartLight™ Endoscopic Ablation System's Notable Treatment Results for Paroxysmal Atrial Fibrillation 3Lexicon Pharmaceuticals Announces Webcast of 2011 Annual R&D Day 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: