Navigation Links
Hundreds of Donor Kidneys Tossed Away Each Year
Date:4/1/2010

But organs infected with hepatitis C are fine for patients with the disease, study finds

THURSDAY, April 1 (HealthDay News) -- Every year, hundreds of kidneys are thrown out because they may be infected with hepatitis C, but they could help many hepatitis C-infected patients waiting for a transplant, Johns Hopkins researchers report.

In fact, since 1995, more than 3,500 kidneys infected with hepatitis C were thrown away. Using hepatitis C-infected kidneys has been controversial, in part due to a 1 percent difference in one-year survival and a 2 percent difference in three-year survival among these patients, the researchers noted.

"Patients with hepatitis C who have kidney failure could very much benefit from these kidneys from hepatitis C-positive donors," said lead researcher Dr. Dorry L. Segev, an associate professor of surgery at Johns Hopkins.

Of the more than 3,500 kidneys thrown away, more than 1,000 came from "what would be considered perfect donors," he said.

The small risk of a hepatitis C-positive patient dying after receiving a hepatitis C-infected kidney is offset by the risk of waiting for a hepatitis C-free kidney, Segev added.

The report is published in the March 31 online edition of the American Journal of Transplantation.

For the study, Segev's team looked at data on 93,825 kidney donors from 1995 to 2009. The researchers found that kidneys infected with hepatitis C were 2.5 times more likely to be discarded than kidneys without the infection.

Since 1995, 3,562 hepatitis C-infected kidneys have been lost, the researchers noted. Many of these hepatitis C-infected kidneys would have been perfectly suited to people already infected with the disease who are on dialysis and the kidney transplant list, Segev said.

Segev's group found that one-third of the transplant centers in the United States do not use any kidneys infected with hepatitis C for hepatitis C-infected patients. On the other hand, 13 percent of transplant centers transplanted more than 50 percent of their hepatitis C-infected patients with kidneys infected with the disease.

During the study period, some 4,800 hepatitis C patients got hepatitis C-negative kidneys. "Using hepatitis C-positive kidneys in people who are infected with the virus could help those with hepatitis C and also expand the organ supply for everyone," Segev said.

Among patients with kidney failure, about 12 percent are infected with hepatitis C. These patients are at increased risk of death on dialysis compared with those without the virus, the researchers said.

In addition, these patients who are waiting for a non-infected kidney wait longer for a transplant -- more than a year longer than other patients, increasing their risk of dying 10 percent to 15 percent during the extra year of waiting, Segev noted.

Segev pointed out that some people think hepatitis C-infected kidneys can be successfully transplanted into patients without hepatitis C. "We are not advocating that," he said.

"We are strictly advocating the fact that there are thousands of perfectly good hepatitis C kidneys that are thrown away, while hepatitis C-positive recipients are sitting there on the waiting list incurring a huge risk of dying while waiting for a different organ," Segev said.

Dr. David Roth, the Wm. Way Anderson Professor of Nephrology and medical director of renal transplantation at the University of Miami Miller School of Medicine, said the types of kidneys used for transplant have been expanded.

"In this day and age we look really hard at different types of groups of organ donors, because there are so many people on the list that we have extended the boundaries of what might have been considered an acceptable or unacceptable kidney," Roth said.

There are patients infected with hepatitis C that "could benefit in years of life and quality of life by getting off of dialysis and receiving a kidney from such a donor," Roth said.

More information

For more information on kidney transplantation, visit the U.S. National Institute of Diabetes, Digestive and Kidney Diseases.



SOURCES: Dorry L. Segev, M.D., Ph.D., associate professor, surgery, Johns Hopkins University School of Medicine, Baltimore; David Roth, M.D., Wm. Way Anderson Professor of Nephrology, medical director, renal transplantation, University of Miami Miller School of Medicine; March 31, 2010, American Journal of Transplantation, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Raising Millions for Team Challenge through Rock ‘n' Roll Las Vegas Half Marathon Program Brings Hundreds From Across the Country to Raise Funds for Crohn's & Colitis
2. Bariatric Advantage Sets a Milestone in "Giving" with RECOVER Program Reaching Hundreds of Needy Weight Loss Surgery Patients in 2009
3. Compton's by Britannica Revised for 2010; Hundreds of Articles Rewritten, Hundreds of New Photos, Images
4. Hundreds of Georgia School Children to Receive Free Eye Exams and Glasses
5. Give The Ultimate Gift of Love This Valentines Day: Become A Registered Organ and Tissue Donor
6. International Breast Milk Project Delivers Donor Breast Milk to Orphaned and Sick Babies in Haiti
7. 69-Year-Old Grandmother Needing A Lifesaving Kidney Transplant Finds a Miracle on the Internet: a 25-Year-Old Living Altruistic Organ Donor Stranger
8. Philadelphia Red Cross Blood Workers Strike to Protect Donor and Blood Safety
9. East Coast Fertility Aims to Build Families One Baby at a Time by Applying Single Embryo Transfers to Donor Egg Program
10. Heart Failure Patient Supported By DuraHeart™ Left-Ventricular Assist System Receives Successful Donor Transplant After Four Years On Device
11. January Is National Blood Donor Month
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2017)... ... June 26, 2017 , ... A new and improved Orgasm-Shot ... look and feel about themselves and their sexual encounters. A unique medical practice ... leakage head on with a ground breaking medical technique aimed to give women ...
(Date:6/26/2017)... ... 2017 , ... KICKICO , a protocol built on Ethereum for more ... catastrophic issues within funding campaigns. KICKICO developers are testing the platform, which will launch ... raising of funds through the power of many - has been around for about ...
(Date:6/25/2017)... ... ... lyric music video in Final Cut Pro X with ProLyric from Pixel Film Studios. Users ... to any song. ProLyric flies in the text for each section and it hovers around ... for optimal control. ProLyric makes editing any music video or text-based production easier than ever. ...
(Date:6/25/2017)... ... June 25, 2017 , ... CareSet Labs released the ... New Orleans. This is a new, greatly improved version of the Doctor Referral teaming ... requests by Fred Trotter and subsequently called the the “Doctor Referral Dataset” as released ...
(Date:6/24/2017)... ... June 24, 2017 , ... ... testing for medications in select Florida and Texas doctors' offices and clinics. This ... new application of genetic testing recognizes the role genes play in determining an ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... Inc., a biotechnology company focused on the development of novel ... and Head of Virology Kristin Bedard has been invited to ... Beyond meeting sponsored by Life Science Washington.  This Symposium ... PDT at the Agora Conference Center in Seattle, ... joined by other leaders in infectious disease research and the ...
(Date:6/10/2017)... , June 9, 2017  Shane K. Burchfield, DPM, is ... for excellence as a Podiatrist in Alabama . ... at Family First Foot Care. He brings over 20 years of ... pain management and healthcare, to his role. ... Foot Care, PC is pleased to welcome you to ...
(Date:6/9/2017)... INDIANAPOLIS , June 9, 2017 /PRNewswire/ ... diabetes. In a further effort to help spread lessons ... this condition, the International Diabetes Federation (IDF) and Eli ... come together for the second phase of the Bringing ... (BRIDGES 2), reaffirming their commitment to helping people with ...
Breaking Medicine Technology: