Navigation Links
Human stem cells from fat tissue fuse with rat heart cells and beat
Date:2/28/2011

If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal (http://www.fasebj.org), scientists have successfully fused human stem cells derived from subcutaneous adipose (fat) tissue with muscle cells from rat hearts. Not only did these cells "talk" to form new muscle cells altogether, but they actually beat.

"Recovery of regenerative cells located in the stromal vascular fraction of a patient's own subcutaneous tissue is relatively simple and can be used for self-healing," said Christopher Alt, Ph.D., a researcher involved in the work from the Department of Molecular Pathology at the University of Texas in Houston. "A patient's quality of life can be improved by application of those recovered regenerative cells to the heart, as well as to bone, tendons, non-healing wounds and joints."

Using newborn rats, scientists studied the combination of rat heart muscle cells (cardiomyocytes) and human adipose (fat) stem cells derived from human subcutaneous adipose tissue. They found that the two fused and formed new heart muscle cells with several nuclei. When kept in a culture environment, these cells beat. These new cells exhibited an ability to compensate for a loss of cardiomyocytes as following a myocardial infarction, via fusion with cardiomyocytes. Furthermore, this study shows that contrary to previous findings suggesting that genetic modification of certain embryonic genes in adult stem cells is required as a prerequisite for turning into heart cells, the human stem cells used in this study were not genetically modified.

"Much work is still ahead before this method can be applied to humans, but the hope is that this technique might eventually make heart transplants unnecessary," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "This study not only shows t
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. A guide star lets scientists see deep into human tissue
2. Fossil Suggests Humans Walked Upright 3 Million Years Ago
3. Rice University technology in human trials to spot cardiac disease, cancer, drug abuse
4. Transplanted human placenta-derived stem cells show therapeutic potential in stroke models
5. Cancer-targeting investigational nanoparticle receives FDA IND approval for first-in-human trial
6. Wild Hogs in Texas Pose Infection Risk to Humans
7. Researchers reveal function of novel molecule that underlies human deafness
8. Illegal use of human growth hormone common among young male weightlifters
9. Like humans, amoebae pack a lunch before they travel
10. Speaker series highlights the role of animals in human culture
11. Obesity in horses could be as high as in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Park City, Utah (PRWEB) September 19, 2014 ... Solution, published new information on why to switch employees ... Benefits, though many employees may be more familiar with ... individual health insurance that makes employees happier. , ... employees are happier with individual health insurance rather than ...
(Date:9/18/2014)... Mary Ann Thompson and Mathieu Nikel decided it was time to ... their son, Isaac, said there was only one choice for them ... 2001 when Thompson was an undergraduate student and needed a French ... time, was French and so she asked him. , ... when she was 7 years old. Nikel is originally from ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 Active Aging ... and older as fully participating members of society and ... To celebrate, The Stafford – a boutique retirement community ... – will host two screenings of Cyber-Seniors - a ... for our residents to watch this great film,” says ...
(Date:9/18/2014)... world have issued a plea to researchers, academics, drug ... research and clinical trials for advanced breast cancer, a ... there are many unanswered questions. , In the latest ... cancer, published simultaneously in the leading cancer journals ... [1] today (Friday), the experts say that further research ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 Memorial ... made history this week by performing the first ever, ... UNOS (United Network for Organ Sharing) approval to launch ... one of only two programs in South Florida. ... Dr. Enrique Gongora, Medical Director of the ...
Breaking Medicine News(10 mins):Health News:Zane Benefits Publishes New Information on Why Employees Are Happier with Individual Health Insurance 2Health News:For The First Time in Over a Decade Mercy College Alumni Marry at College 2Health News:In Support of Active Aging Week, a Lake Oswego Retirement Community Will Get a Sneak Peek at an Inter-Generational Documentary – Cyber-Seniors 2Health News:Experts issue plea for better research and education for advanced breast cancer 2Health News:Experts issue plea for better research and education for advanced breast cancer 3Health News:Experts issue plea for better research and education for advanced breast cancer 4Health News:Experts issue plea for better research and education for advanced breast cancer 5Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 3Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 4
... Reporter , MONDAY, Dec. 5 (HealthDay News) -- Eating ... salmon, may significantly lower a young woman,s risk of ... that women of childbearing age who never ate fish had ... often, and a 90 percent higher risk than women who ...
... has seen a dramatic increase in the presence of ... the stigmatized stereotype of gays into a new, socially ... marketing strategy affects the way gays understand themselves and ... explains Wan-Hsiu Sunny Tsai, assistant professor of advertising at ...
... By Jenifer Goodwin HealthDay Reporter , MONDAY, ... epilepsy drug valproate have a nearly three times higher ... finds. Researchers in Denmark used national birth data ... between 1996 and 2006 to 428,000 women. Using a ...
... , MONDAY, Dec. 5 (HealthDay News) -- A ... in the teenage brain. The research found that teens who,ve ... contains brain cells -- in some areas of the brain ... involved in the study had a history of abuse or neglect. ...
... Ky. -- University of Kentucky researchers recently received a ... in Appalachia. The grant gives the team $225,000 ... additional years that could total $675,000. It is funded ... the UK-based Rural Cancer Prevention Center. Published studies ...
... Respirology reveals that dust storms have an adverse ... known as chronic obstructive pulmonary disease (COPD). Dust storms ... dust that travels long distances from North China. The concentrations ... 10 micrometerscan reach very high levels. Researchers led by ...
Cached Medicine News:Health News:Fish May Cut Threat of Heart Disease in Young Women 2Health News:Fish May Cut Threat of Heart Disease in Young Women 3Health News:How advertising shapes the image of gayness in America 2Health News:Fetal Exposure to Epilepsy Drug Might Raise Autism Risk: Study 2Health News:Fetal Exposure to Epilepsy Drug Might Raise Autism Risk: Study 3Health News:Abuse in Childhood May Alter Teen Brain 2Health News:University of Kentucky researchers awarded CDC grant to study cancer survival in Appalachia 2
(Date:9/18/2014)... , Sept. 18, 2014   3D Systems   ... the Simbionix RobotiX Mentor™ , a new robotic surgery ... the first time at the ERUS exhibition in ... (booth #7). Robotic-assisted minimally invasive surgery represents a ... means the needs for training for robotic surgery has increased, ...
(Date:9/18/2014)... After 6 months of careful research ... - the new programme for the next Cool Chain & ... global Cool Chain series, has just been released! ... As the lines between supply chain, logistics, QA and purchasing ... is broad and yet specific, focused and yet accessible, inclusive ...
(Date:9/18/2014)... new expert panel report, Improving Medicines for Children ... by the Council of Canadian Academies, addresses the importance ... year about half of Canada,s ... Much of this prescribing is done off-label (i.e. the ... risks. Children have historically been excluded in ...
Breaking Medicine Technology:3D Systems Introduces New Simbionix Robotics Training Platform 23D Systems Introduces New Simbionix Robotics Training Platform 3Europe's Biggest and Longest-Running Gathering of Life Sciences Logistics, Supply Chain & QA Professionals 2Studying medicines in children is always possible and is in their best interest, finds Expert Panel 2Studying medicines in children is always possible and is in their best interest, finds Expert Panel 3
... Sept. 10 National Jewish Health and,Roche ... to pursue,opportunities in the growing field of ... expertise in clinical testing,and care for patients ... technology to bring new diagnostic solutions to,the ...
... September 10 Circassia Ltd, a,specialty biopharmaceutical ... announced positive results from a phase II ... the field of cat allergy.,The trial showed ... to the allergen that causes most cat ...
Cached Medicine Technology:National Jewish Health and Roche Diagnostics Corporation Reach Agreement to Pursue Environmental Molecular Diagnostics Opportunities 2Circassia Achieves Successful Phase II Clinical Results With Toleromune(R) Anti-Allergy Technology 2Circassia Achieves Successful Phase II Clinical Results With Toleromune(R) Anti-Allergy Technology 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: