Navigation Links
Human papillomavirus types do not replace others after large-scale vaccination
Date:7/24/2012

Vaccines against human papillomavirus (HPV) are now recommended by the Centers for Disease Control and Prevention for both teenage boys and girls. The vaccine protects against the two most common types of the virus that cause cervical cancer: HPV 16 and 18. Is there a chance that the increased number of people vaccinated might result in an increase of other types of HPV that cause cancer?

A UNC-led international team of scientists studied this question in a group of 2228 Kenyan men as a "nested" trial in a larger trial. Their first paper in the Journal of Infectious Diseases showed that little evidence exists for potential HPV type competition in a cross-sectional study. Viral type competition occurs when different types of a particular virus compete for dominance.

Their new work is reported in the June 18, 2012 early online issue of the Journal of Infectious Diseases. Using prospective data, their study presents the first epidemiological data in men on the type-specific associations between prevalent HPV infections and future acquisition of other HPV types.

Jennifer Smith, PhD, MPH, study senior author explains, "We found no evidence for competition between different HPV types over time in high-risk men from Kenya. While these data are based only on non-vaccinated men, our findings are of potential importance because they suggest that HPV types are generally acting independently from one another, and thus it is unlikely that HPV type-replacement will occur following large scale vaccination programs of young male adolescents."

Dr. Smith is an associate professor of epidemiology in the UNC Gillings School of Global Public Health and a member of UNC Lineberger Comprehensive Cancer Center.

With the recent approval of prophylactic HPV vaccination of young men, data are needed to understand if patterns of HPV acquisition differ among men with specific HPV type infections as compared to men without these HPV infections. The effect of current vaccine-relevant HPV infections on the subsequent acquisition of different HPV types could impact the long-term potential for HPV type replacement following population-based HPV vaccination.


'/>"/>

Contact: Dianne G. Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Source:Eurekalert

Related medicine news :

1. Novel pig model may be useful for human cancer studies
2. Study Gives First Evidence That Adult Human Lungs Can Regrow
3. Mouse With Human-Like Immune System Could Advance AIDS Research
4. SIgN scientists discover dendritic cells key to activating human immune responses
5. UW scientists discover why human body cannot fight HIV infection
6. Toward new drugs for the human and non-human cells in people
7. Dogs May Mourn as Deeply as Humans Do
8. Moffitt researchers find cutaneous human papillomavirus infection a risk factor for skin cancer
9. Human Kinetics Author Rich Elliott Wins Prestigious Cordner Nelson Book Award
10. Bees shed light on human sweet perception and metabolic disorders
11. Human model of Huntingtons disease created from skins stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader ... been awarded a contract by the Center for Medicare and Medicaid Services (CMS). ... the enterprise use of Agile methodologies in a consistent and high value manner ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... The American ... Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium ... 8. , In honor of Morris F. Collen, a pioneer in the field of ...
(Date:10/12/2017)... PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B ... York City on October 11, 2017. , The annual award competition recognizes editorial and ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... PHILADELPHIA , Oct. 2, 2017 Halo Labs announces ... particle analysis system called the HORIZON at MIBio 2017 in ... analyzes subvisible and visible particulate matter in biopharmaceutical samples with unprecedented ... use of the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
(Date:9/27/2017)... Sept. 27, 2017  Commended for their devotion to personalized ... Ranked as number one in the South Florida Business Journal,s ... Inc. 5000 yearly list, the national specialty pharmacy has found ... Bardisa will soon be honored by SFBJ as the ... Set to receive his award in October, Bardisa ...
(Date:9/23/2017)... Janssen Biotech, Inc. (Janssen) announced today that ... U.S. Food and Drug Administration (FDA) for the Biologics ... treatment of moderately to severely active rheumatoid arthritis (RA). ... needed to further evaluate the safety of sirukumab in ... "We are disappointed ...
Breaking Medicine Technology: