Navigation Links
Human papillomavirus types do not replace others after large-scale vaccination
Date:7/24/2012

Vaccines against human papillomavirus (HPV) are now recommended by the Centers for Disease Control and Prevention for both teenage boys and girls. The vaccine protects against the two most common types of the virus that cause cervical cancer: HPV 16 and 18. Is there a chance that the increased number of people vaccinated might result in an increase of other types of HPV that cause cancer?

A UNC-led international team of scientists studied this question in a group of 2228 Kenyan men as a "nested" trial in a larger trial. Their first paper in the Journal of Infectious Diseases showed that little evidence exists for potential HPV type competition in a cross-sectional study. Viral type competition occurs when different types of a particular virus compete for dominance.

Their new work is reported in the June 18, 2012 early online issue of the Journal of Infectious Diseases. Using prospective data, their study presents the first epidemiological data in men on the type-specific associations between prevalent HPV infections and future acquisition of other HPV types.

Jennifer Smith, PhD, MPH, study senior author explains, "We found no evidence for competition between different HPV types over time in high-risk men from Kenya. While these data are based only on non-vaccinated men, our findings are of potential importance because they suggest that HPV types are generally acting independently from one another, and thus it is unlikely that HPV type-replacement will occur following large scale vaccination programs of young male adolescents."

Dr. Smith is an associate professor of epidemiology in the UNC Gillings School of Global Public Health and a member of UNC Lineberger Comprehensive Cancer Center.

With the recent approval of prophylactic HPV vaccination of young men, data are needed to understand if patterns of HPV acquisition differ among men with specific HPV type infections as compared to men without these HPV infections. The effect of current vaccine-relevant HPV infections on the subsequent acquisition of different HPV types could impact the long-term potential for HPV type replacement following population-based HPV vaccination.


'/>"/>

Contact: Dianne G. Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Source:Eurekalert

Related medicine news :

1. Novel pig model may be useful for human cancer studies
2. Study Gives First Evidence That Adult Human Lungs Can Regrow
3. Mouse With Human-Like Immune System Could Advance AIDS Research
4. SIgN scientists discover dendritic cells key to activating human immune responses
5. UW scientists discover why human body cannot fight HIV infection
6. Toward new drugs for the human and non-human cells in people
7. Dogs May Mourn as Deeply as Humans Do
8. Moffitt researchers find cutaneous human papillomavirus infection a risk factor for skin cancer
9. Human Kinetics Author Rich Elliott Wins Prestigious Cordner Nelson Book Award
10. Bees shed light on human sweet perception and metabolic disorders
11. Human model of Huntingtons disease created from skins stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is ... emergency ambulance transport experience for the millions of people who require these medical ... the taxi industry through the use of technology. Now, SmartEMS has put forth ...
(Date:6/26/2016)... ... 26, 2016 , ... PawPaws brand pet supplements owned by Whole ... enhance the health of felines. The formula is all-natural and is made from Chinese ... PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Medical Market Analysis 2016 - Forecast to 2022" report ... The report contains up to date financial data derived from ... of major trends with potential impact on the market during ... market segmentation which comprises of sub markets, regional and country ...
Breaking Medicine Technology: