Navigation Links
Human clinical trial of NIH-developed dengue vaccine begins
Date:8/9/2010

After more than a decade of development at the National Institutes of Health, a vaccine to prevent infection by the mosquito-borne dengue virus has begun human clinical testing. The vaccine was developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID) and is undergoing clinical study at the Johns Hopkins Bloomberg School of Public Health in Baltimore.

About 2.5 billion people in more than 100 countries worldwide live in areas where they are at risk of dengue infection. "This is an important milestone for NIAID's intramural scientists in the development of a model dengue vaccine, which could potentially have a major impact in preventing dengue," says NIAID Director Anthony S. Fauci, M.D. "With increasing infection rates and disease severity around the world and the discovery of dengue in parts of Florida, finding a way to prevent dengue infection is an important priority."

Dr. Fauci is co-author of a 2008 commentary in the Journal of the American Medical Association that raised awareness of dengue as an emerging infectious disease.

Dengue fever is caused by any of four related viruses DENV-1, DENV-2, DENV-3 and DENV-4 which are transmitted to humans by Aedes mosquitoes. Dengue virus is prevalent in the tropical and subtropical regions of the world and each year infects about 50 million to100 million people. It accounts for 25,000 deaths annually, most of them in children.

Most people infected with dengue virus experience no symptoms at all or only a mild fever. Others develop flu-like symptoms, headache, and joint and muscle pain. A smaller portion of those infected experience the more severe dengue hemorrhagic fever/shock syndrome (DHF/DSS), which can cause high fever, pain, bleeding, a drop in blood pressure, and, in some cases, coma or death.

There is no vaccine to prevent dengue infection or drug treatment for those who become infected. Current treatment recommendation
'/>"/>

Contact: Nalini Padmanabhan
padmanabhannm@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Actor and Humanitarian Harrison Ford Assists Operation Smiles Relief Efforts in Haiti
2. Human Dental Technology Leads to Breakthroughs for Pet Dental Health at Sergeants Pet Care Products, Inc.
3. Scripps Health Begins Pioneering Study of Human Tumor Sequencing in Cancer Patients
4. New drug for kidney transplant recipients effective in humans
5. Agility Consulting Partners with pan (Performance Assessment Network) to Bring Custom Private Label Assessment Capability to Human Resource Professionals and Consultants
6. Dolphins health shed light on human and ocean health
7. Dolphins could be ideal model to study human cervical cancer, UF veterinarians say
8. Dolphins May Warn of Health Risks in Humans
9. Inadequate access to opioid-based pain relief is a human rights issue for cancer patients
10. Sociologist expands US conversation on human rights
11. State of Oregon Department of Human Services Selects Netsmart Technologies for Comprehensive Behavioral Healthcare Integration Project
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 30, 2014 This two-day, advanced ... vestibular sequellae that may arise following a concussion ... concussions can be varied, from sports related injuries, car ... sustained by the thousands of returning soldiers from war ... blast and blunt traumas can result in similar injuries, ...
(Date:9/30/2014)... Amy Norton ... News) -- Long-acting contraceptive devices should be the first ... from the American Academy of Pediatrics state. Although ... pills, two other forms of contraception -- intrauterine devices ... according to the academy. And they should be ...
(Date:9/30/2014)... HealthDay Reporter , MONDAY, Sept. ... broad-spectrum antibiotics before the age of 2 may face ... new research suggests. Broad-spectrum antibiotics target a larger ... study. "It is a reason to think about ... picking," said lead researcher Dr. Charles Bailey, attending physician ...
(Date:9/30/2014)... Thompson HealthDay Reporter MONDAY, ... receive medical implants -- artificial valves, hip replacements, surgical mesh ... tested before or after their approval by the U.S. Food ... -- conducted by prominent nonprofit groups and published online Sept. ... blame for inadequate medical device testing on lax oversight by ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 ... provider in the nation, today announced that Adam ... Healthcare’s anesthesiology division, will present at the Society ... SHSMD Connections 2014 . The conference will ... , SHSMD Connections is a four-day conference that ...
Breaking Medicine News(10 mins):Health News:North American Seminars Presents Traumatic Brain Injury and Concussions in Conduction with St. Anthony's Medical Center in St. Louis, MO on November 8-9, 2014 2Health News:North American Seminars Presents Traumatic Brain Injury and Concussions in Conduction with St. Anthony's Medical Center in St. Louis, MO on November 8-9, 2014 3Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 2Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 3Health News:Antibiotic Use Before Age 2 Might Raise Obesity Risk, Study Says 2Health News:Antibiotic Use Before Age 2 Might Raise Obesity Risk, Study Says 3Health News:Medical Implant Devices Skate Through Review Process, Studies Claim 2Health News:Medical Implant Devices Skate Through Review Process, Studies Claim 3Health News:Medical Implant Devices Skate Through Review Process, Studies Claim 4Health News:Sheridan Healthcare Anesthesiologist to Present at Society for Healthcare Strategy & Market Development Conference 2Health News:Sheridan Healthcare Anesthesiologist to Present at Society for Healthcare Strategy & Market Development Conference 3
... has announced,the appointment of Florence L. DiBenedetto as senior ... January 5, 2009, succeeding longtime,General Counsel Gary Loveridge who ... Formerly senior partner of the Sacramento-based law firm Hunter ... decades, DiBenedetto,served for more than 10 years as the ...
... Progressive Lenses and Transitions® Lenses to Produce Optimal Visual Experience ... ... Two of the most distinguished names in the optical industry are ... ,Carl Zeiss Vision, a leader for 160 years in precision optics, ...
... Dec. 17 Hologic, Inc. (Nasdaq: HOLX ), ... imaging systems and surgical products dedicated to serving the healthcare ... quarter fiscal 2009 operating results on Monday, February 2, 2009 ... host a conference call on Monday, February 2, 2009 at ...
... eggs to fertility clinics reported satisfaction with the process, ... 20 percent reported lasting psychological effects, according to the ... , The research by scientists at the University of ... 20 states and is the largest study to explore ...
... 1 Million Prescriptions , , ... wholly owned subsidiary of the Cystic Fibrosis Foundation, today announced ... cystic fibrosis (CF) community nationwide. , , ... patient, one prescription and a mission to improve access to ...
... to Meet Joint Commission Compliance through Patient Engagement , ... In an effort to improve patient safety and standards ... Patient Care (IPC) solutions, is enabling King,s Daughters Medical Center ... Patient Safety Goal (NPSG) 16 through GetWellNetwork,s interactive PatientLife ...
Cached Medicine News:Health News:Sutter Health Welcomes New General Counsel 2Health News:Carl Zeiss Vision and Transitions Optical Inc. Promote Pioneering Eyewear to Consumers 2Health News:Hologic, Inc. to Release First Quarter Fiscal 2009 Operating Results on Monday, February 2, 2009 2Health News:Most women report satisfaction with egg donation; some claim problems 2Health News:Most women report satisfaction with egg donation; some claim problems 3Health News:Cystic Fibrosis Services Pharmacy Celebrates 20th Anniversary 2Health News:King's Daughters Medical Center Leverages Unique Bedside Interactive Technology to Meet Requirements of Patient Safety Goal 16 2Health News:King's Daughters Medical Center Leverages Unique Bedside Interactive Technology to Meet Requirements of Patient Safety Goal 16 3
(Date:9/30/2014)... 2014 In a recent study ... backflow of the Eldor spinal needle 25G, 103 mm ... pencil point spinal needles of the same gauge and ... anesthesia is an excellent type of regional anesthesia for ... etc. It is estimated that 100 million ...
(Date:9/30/2014)... September 2014 ... Acutus Medical, Inc. ... 3D-Herzkammer-Bildgebungs- und Dipoldichte-Mappingsystem in Echtzeit zur ... komplexen Herzrhythmusstörungen einschließlich Vorhofflimmern führen bzw. ... zusätzlichen Finanzierung über 26,2 Mio. USD ...
(Date:9/30/2014)... Sept. 30, 2014  The orthopedic specialists at Midwest ... 6 orthopedic group by US News & World Report, ... series of free, public seminars to discuss partial and ... world come to see the knee physicians at Midwest ... available at Munster Specialty Surgery Center. ...
Breaking Medicine Technology:Acutus Medical, Inc. schließt zusätzliche Finanzierungsrunde Serie B über 26,2 Mio. USD ab, um Portfolio-Erweiterung zu finanzieren 2Acutus Medical, Inc. schließt zusätzliche Finanzierungsrunde Serie B über 26,2 Mio. USD ab, um Portfolio-Erweiterung zu finanzieren 3"Knee Pain Solutions for Active Adults" Complimentary Seminars Open to the Public 2
... 20 In an effort to ... supply chain, Siemens Healthcare Diagnostics (Siemens) has published product data ... U.S. product line into the GHX Health ConneXion(SM) data pool. ... GS1,s Global Data Synchronization Network (GDSN®) that is focused solely ...
... Kinetic Systems, Inc., a leading global provider of process ... clients, announced today the appointment of Peter M. Maris ... to its Board of Directors. He will also continue ... Mr. Maris has been with Kinetics for more than ...
Cached Medicine Technology:Siemens Healthcare Diagnostics Publishes Global Trade Item Numbers (GTINs) for its Entire U.S. Product Line to the GHX Health ConneXion(SM) Data Pool 2Siemens Healthcare Diagnostics Publishes Global Trade Item Numbers (GTINs) for its Entire U.S. Product Line to the GHX Health ConneXion(SM) Data Pool 3Kinetic Systems Appoints Peter M. Maris President & Chief Executive Officer 2
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
Inquire...
Inquire...
Inquire...
Medicine Products: