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Human Stem Cells Used to Fix Damaged Mouse Heart
Date:7/18/2011

imitations of cell therapy for cardiovascular diseases has been the survival of cardiac progenitors cells implanted into the heart. In certain studies, more than 90 percent of these implanted cells die after injection into the diseased hearts, decreasing their ability to repair the hearts."

In this new study, the researchers showed that by expressing the gene Pim1, the team was "able to enhance the reparative capacity of these cells. This is an important study addressing an unmet need in the field of stem cell therapy."

While the study results are encouraging, experts note that research involving animals frequently doesn't lead to medical advances that benefit people.

More information

The U.S. National Institutes of Health provides more information on stem cells.

-- Mary Elizabeth Dallas

SOURCES: American Heart Association, news release, July 18, 2011; Roger Hajjar, MD, professor medicine, cardiology, and professor gene and cell medicine, Mount Sinai School of Medicine, New York City


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